The renal transport of hippurate and protein‐bound solutes

Autor: Rohit Kumar, Avinash Adiga, Joshua Novack, Alex Etinger, Lawrence Chinitz, James Slater, Henriette deLoor, Bjorn Meijers, Robert S. Holzman, Jerome Lowenstein

Publikováno v: Physiological Reports, Vol 8, Iss 4, Pp n/a-n/a (2020)

Abstract Measurement of the concentration of hippurate in the inferior vena cava and renal blood samples performed in 13 subjects with normal or near‐normal serum creatinine concentrations confirmed the prediction that endogenous hippurate was clea

Externí odkaz: https://doaj.org/article/e63e2632af6b4768bb037e4a496de80a

The renal transport of hippurate and protein‐bound solutes

Autor: James Slater, Henriette de Loor, Björn Meijers, Joshua Novack, Jerome Lowenstein, Alex Etinger, Robert S. Holzman, Avinash Adiga, Rohit Kumar, Lawrence Chinitz

Publikováno v: Physiological Reports
Physiological Reports, Vol 8, Iss 4, Pp n/a-n/a (2020)

Measurement of the concentration of hippurate in the inferior vena cava and renal blood samples performed in 13 subjects with normal or near‐normal serum creatinine concentrations confirmed the prediction that endogenous hippurate was cleared on a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04f7db8832e2a902d59894aed0b735ff
https://doi.org/10.14814/phy2.14349

Uremic toxin concentrations are related to residual kidney function in the pediatric hemodialysis population

Autor: Wim Van Biesen, Charlotte Samaille, Karolis Azukaitis, Ann Raes, Claus Peter Schmitt, Maria Van Dyck, Koen Van Hoeck, Brankica Spasojevic, Franz Schaefer, Griet Glorieux, Constantinos J. Stefanidis, Sunny Eloot, Michel Fischbach, Raymond Vanholder, Lukasz Obrycki, Els Holvoet, Johan Vande Walle, Saoussen Krid, Fabio Paglialonga, Varvara Askiti, Mieczysław Litwin, Nathalie Godefroid, Evelien Snauwaert, Sanne Roels, Aysun Karabay Bayazit, Bruno Ranchin, Laure Collard, Nur Canpolat, Rukshana Shroff

Publikováno v: TOXINS
Toxins
Toxins, Vol 11, Iss 4, p 235 (2019)
Toxins, Basel : MDPI AG, 2019, vol. 11, iss. 4, art. no. 235, p. [1-15]
Volume 11
Issue 4
Toxins, Vol. 11, no. 4, p. 235 [1-15] (2019)

Protein-bound uremic toxins (PBUTs) play a role in the multisystem disease that children on hemodialysis (HD) are facing, but little is known about their levels and protein binding (%PB). In this study, we evaluated the levels and %PB of six PBUTs cr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ed03ecb4838761f5d72acb01989aef4
https://hdl.handle.net/20.500.12605/22449

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Acarbose treatment lowers generation and serum concentrations of the protein-bound solute p-cresol: A pilot study

Autor: Pieter Evenepoel, Bert Bammens, Kristin Verbeke, Yves Vanrenterghem

Publikováno v: Kidney International. 70:192-198

Several protein-bound uremic retention solutes (including p -cresol) originate from colonic bacterial fermentation of protein. Higher colonic availability of carbohydrates drives this process towards lower production of toxic metabolites. Small intes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::058481932c145169c7d909e190769096
https://doi.org/10.1038/sj.ki.5001523