Zobrazeno 1 - 10 of 225 pro vyhledávání: '"protéine kinase"'
1
Protein Kinase CK2 Acts as a Molecular Brake to Control NADPH Oxidase 1 Activation and Colon Inflammation
Autor: Liu, Dan, Marie, Jean-Claude, Pelletier, Anne-Laure, Song, Zhuoyao, Ben-Khemis, Marwa, Boudiaf, Kaouthar, Pintard, Coralie, Leger, Thibaut, Terrier, Samuel, Chevreux, Guillaume, El-Benna, Jamel, Dang, Pham My-Chan
Publikováno v: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, 2022, 13 (4), pp.1073-1093. ⟨10.1016/j.jcmgh.2022.01.003⟩
International audience; BACKGROUND & AIMS: NADPH oxidase 1 (NOX1) has emerged as a prime regulator of intestinal mucosa immunity and homeostasis. Dysregulation of NOX1 may cause inflammatory bowel disease (IBD). It is not clear how NOX1 is regulated
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a0d262c7f56dca6454e597cf2438a8e
https://doi.org/10.1016/j.jcmgh.2022.01.003
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2
Real-life data on protein kinase inhibitors in chronic myeloid leukemia : usage profile in France and impact of drug interactions with concomitant treatments
Autor: Pajiep Tchapda, Marie Christelle
Publikováno v: Pharmacologie. Université Paul Sabatier-Toulouse III, 2022. Français. ⟨NNT : 2022TOU30090⟩
The introduction of protein kinase inhibitors (PKIs) in the treatment of chronic myeloid leukemia (CML) has considerably changed the paradigm of this pathology, which has now become a chronic disease. This chronicity is accompanied over time by an in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1398::7ffcd3c43582c6cad26b8528dc5ba604
https://theses.hal.science/tel-03813857
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3
RNA interference : a strategy for targeting protein kinase B (Akt) in hepatocellular carcinoma
Autor: Mroweh, Mariam
Publikováno v: Virologie. Université Grenoble Alpes [2020-..]; Université Libanaise, 2022. Français. ⟨NNT : 2022GRALV031⟩
Hepatocellular carcinoma (HCC) is one of the most common causes of cancer-related deaths worldwide, and its incidence is rising. HCC develops almost exclusively on the background of chronic liver inflammation, which can be caused by chronic alcohol c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1398::739f46081ce0883e2ee96da385e9b135
https://theses.hal.science/tel-03771336
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4
ARN interférence : une stratégie pour cibler la protéine kinase B (Akt) dans le carcinome hépatocellulaire
Autor: Mroweh, Mariam
Hepatocellular carcinoma (HCC) is one of the most common causes of cancer-related deaths worldwide, and its incidence is rising. HCC develops almost exclusively on the background of chronic liver inflammation, which can be caused by chronic alcohol c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______166::739f46081ce0883e2ee96da385e9b135
https://theses.hal.science/tel-03771336
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5
Caractérisation d’une nouvelle Tyrosine protéine-kinase et étude de son rôle cellulaire chez la bactérie Streptococcus pneumoniae
Autor: Pelletier, Anaïs
The pathogenic bacterium Streptococcus pneumoniae possesses two protein-kinases CpsD and StkP involved in polysaccharide capsule synthesis and cellular division respectively. Recently, a new bacterial protein-kinase family was identified, named UbK (
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______166::93f39579654af7cb71e9eaeb71e8dfec
https://theses.hal.science/tel-03879644
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7
Myocardial glucotoxicity: Mechanisms and potential therapeutic targets
Autor: Sylvain Battault, Christophe Beauloye, Luc Bertrand, Anne Van Steenbergen, Sandrine Horman, Edith Renguet
Publikováno v: Archives of cardiovascular diseases, Vol. 113, no. 11, p. 736-748 (2020)
Besides coronary artery disease, which remains the main cause of heart failure in patients with diabetes, factors independent of coronary artery disease are involved in the development of heart failure in the onset of what is called diabetic cardiomy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48ed77ecf4059b99913b4f455c19aefc
https://hdl.handle.net/2078.1/248333
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8
Protein kinase CK2 contributes to placental development: physiological and pathological implications
Autor: Nicolas Lemaitre, Claude Cochet, Daniel Vaiman, Déborah Reynaud, Odile Filhol, Mohamed Benharouga, Nadia Alfaidy, Roland Abi Nahed, Solene Lartigue, Caroline Roelants
Publikováno v: Journal of Molecular Medicine
Journal of Molecular Medicine, Springer Verlag, 2020, 98 (1), pp.123-133. ⟨10.1007/s00109-019-01855-0⟩
Journal of Molecular Medicine, 2020, 98 (1), pp.123-133. ⟨10.1007/s00109-019-01855-0⟩
International audience; Preeclampsia (PE) is the most threatening pathology of human pregnancy. Its development is thought to be due to a failure in the invasion of trophoblast cells that establish the feto-maternal circulation. Protein kinase CK2 is
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::384959d647d07304f1114e51f8f6a61c
https://hal.archives-ouvertes.fr/hal-02456988
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9
Design of a research tool for the discovery of new bioactive molecules
Autor: Bournez, Colin
Publikováno v: Chemo-informatique. Université d'Orléans, 2019. Français. ⟨NNT : 2019ORLE3043⟩
Kinases belong to a family of proteins greatly involved in several aspects of cell control including division or signaling. They are often associated with serious pathologies such as cancer. Therefore, they represent important therapeutic targets in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::00571d9da21cc32e4a8a92ac55a32c9a
https://tel.archives-ouvertes.fr/tel-03142661/file/103729_BOURNEZ_2019_archivage.pdf
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