Zobrazeno 1 - 10
of 2 156
pro vyhledávání: '"proprotein convertase subtilisin-kexin type 9"'
Autor:
Dennis Ievan Hakim, Faqrizal Ria Qhabibi, Muhammad Yusuf, Nasim Amar, Indra Prasetya, Ade Meidian Ambari
Publikováno v:
The Egyptian Heart Journal, Vol 76, Iss 1, Pp 1-15 (2024)
Abstract Background Acute coronary syndrome continues to be a significant cardiovascular issue. Statins are commonly acknowledged as medications that reduce LDL-C levels and stabilize plaques. Nevertheless, their efficacy is limited. Presently, PCSK9
Externí odkaz:
https://doaj.org/article/f65d0dab0c5d46c883658a4b3a2d2a8c
Publikováno v:
Tzu-Chi Medical Journal, Vol 36, Iss 4, Pp 360-369 (2024)
A decrease in the levels of low-density lipoprotein receptors (LDLRs) leads to the accumulation of LDL cholesterol (LDL-C) in the bloodstream, resulting in hypercholesterolemia and atherosclerotic cardiovascular diseases. Increasing the expression le
Externí odkaz:
https://doaj.org/article/d9192fc35f1b4bb1bf28bf8e7eb63c93
Publikováno v:
World Journal of Surgical Oncology, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background Pancreatic adenocarcinoma (PAAD) is the most frequent kind of pancreatic cancer (PC). Recent studies suggest that lipid metabolism facilitates tumorigenesis, disease progression, and resistance to therapy by promoting lipid synthe
Externí odkaz:
https://doaj.org/article/2ea145eb7dee46d1b4cb863223b989b3
Autor:
JIA Jia, LIU Jiahui, JI Wenjun, ZHENG Bo, WANG Xingang, FAN Fangfang, LI Yin, ZHANG Long, ZHANG Yan
Publikováno v:
Zhongguo quanke yixue, Vol 27, Iss 36, Pp 4568-4574 (2024)
Background Proprotein convertase subtilisin/kexin type 9 (PCSK9) plays a crucial role in lipid metabolism. The factors influencing PCSK9 in acute myocardial infarction (AMI) patients have not been fully understood. Objective To investigate the influe
Externí odkaz:
https://doaj.org/article/f863c83b6e7e4ccf9686f47c080374f7
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Observational studies suggest dyslipidemia as an atopic dermatitis (AD) risk factor and posit that lipid-lowering drugs may influence AD risk, but the causal link remains elusive. Mendelian randomization was applied to elucidate the causal r
Externí odkaz:
https://doaj.org/article/5b624e49267646ceb4c9d61063934cce
Publikováno v:
Klinicist, Vol 18, Iss 1, Pp 12-30 (2024)
Atherosclerosis is a chronic inflammatory vascular disease caused by various risk factors, in particular smoking, obesity, high blood pressure, and dyslipidemia. In addition, such signaling pathways as NLRP3 inflammasome, toll-like receptors, proprot
Externí odkaz:
https://doaj.org/article/12d8f6151e1f42b5b09708ec729a032f
Autor:
CHEN Renliang, CHEN Fengying
Publikováno v:
Zhongguo linchuang yanjiu, Vol 37, Iss 6, Pp 826-829 (2024)
Coronary heart disease (CHD) is currently an important cause of mortality among residents in China and worldwide. The incidence of CHD in China is increasing annually. Among the various factors leading to the occurrence of CHD, abnormalities in blood
Externí odkaz:
https://doaj.org/article/58e1a145ddbf4d2fb99b144da5b37dc2
Autor:
Ping Lai, Shuquan Xu, Ziyou Liu, Jiayuan Ling, Kejun Tian, Jianwei Yan, Dong Chen, Yiming Zhong, Jinhua Xue
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
BackgroundFollowing the identification of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors, research in this area has experienced significant growth. However, a thorough bibliometric analysis of this burgeoning field remains conspicuo
Externí odkaz:
https://doaj.org/article/e9e7e988e3a34a8daec9427a1dafbeba
Autor:
Jian Gao, Linjie Yuan, Huanyu Jiang, Ganggang Li, Yuwei Zhang, Ruijun Zhou, Wenjia Xian, Yutong Zou, Quanyu Du, Xianhua Zhou
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundPrevious studies have demonstrated that naringenin possesses lipid-lowering effects; however, the underlying mechanisms, particularly its specific molecular targets, remain uncertain.MethodsUsing bioinformatics, three traditional Chinese me
Externí odkaz:
https://doaj.org/article/255615472aea4eb0bf47e381d266f546
Autor:
Frans B. Mensink, Jonathan Los, Rohit M. Oemrawsingh, Clemens von Birgelen, Alexander Ijsselmuiden, Martijn Meuwissen, Jin M. Cheng, Diederik F. van Wijk, Pieter C. Smits, Valeria Paradies, Dirk J. van der Heijden, Himanshu Rai, Tim JF. ten Cate, Cyril Camaro, Peter Damman, Lokien X. van Nunen, Aukelien C. Dimitriu-Leen, Marleen H. van Wely, Aysun Cetinyurek-Yavuz, Robert A. Byrne, Niels van Royen, Robert-Jan M. van Geuns
Publikováno v:
Heliyon, Vol 10, Iss 19, Pp e38077- (2024)
Non-culprit coronary artery lesions are commonly present in patients presenting with an acute coronary syndrome (ACS). Additional stenting of non-culprit lesions in addition to the culprit lesion intends to prevent secondary events caused by these le
Externí odkaz:
https://doaj.org/article/b41e72e1265843fb8be2ceed88f6426d