Zobrazeno 1 - 10
of 2 714
pro vyhledávání: '"prolonged release"'
Leveraging long-acting IL-15 agonists for intratumoral delivery and enhanced antimetastatic activity
Autor:
John A. Hangasky, Rocío del Valle Fernández, Dimitris Stellas, Guillermo Hails, Sevasti Karaliota, Gary W. Ashley, Barbara K. Felber, George N. Pavlakis, Daniel V. Santi
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionIL-15 agonists hold promise as immunotherapeutics due to their ability to induce the proliferation and expansion of cytotoxic immune cells including natural killer (NK) and CD8+ T cells. However, they generally have short half-lives that
Externí odkaz:
https://doaj.org/article/e43365ab5c1643469ee96abce7c5c45e
Autor:
Louise Füessl, Lena Kreuzer, Kajetan Nierychlewski, Tobias Seibt, Manfred Johannes Stangl, Dionysios Koliogiannis, Bruno Meiser, Markus Schwarz, Michael Fischereder, Stephan Kemmner
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
The calcineurin inhibitor tacrolimus, which is available as an immediate- or extended-release formulation, is the standard-of-care immunosuppression after kidney transplantation with low rejection rates, especially in the first year after transplanta
Externí odkaz:
https://doaj.org/article/2b7479eda80d444c8759788f837ec362
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 12, Iss 4, Pp 91-95 (2023)
Introduction. Wet granulation technology is a process of directed particle aggregation of powder materials to obtain required properties of tablet masses and, as a consequence, to achieve satisfactory characteristics of tablets. In this addition, as
Externí odkaz:
https://doaj.org/article/c79202402ab3455fb9eeeaae5eef13fc
Autor:
M. V. Zamergrad, V. A. Parfenov, A. S. Agafina, N. V. Lyamina, M. M. Gavrik, L. R. Kuchumova, E. R. Barantsevich, V. S. Krasnov, A. A. Ivanova, A. L. Vladykin, K. А. Ishchenko
Publikováno v:
Неврология, нейропсихиатрия, психосоматика, Vol 15, Iss 5, Pp 20-34 (2023)
Functional dizziness (FD) is one of the most common causes of chronic dizziness for which there is no effective drug therapy, highlighting the importance of searching for new treatment technologies.Objective: to evaluate the efficacy and safety of Ve
Externí odkaz:
https://doaj.org/article/66ffed64510144338a6f4beca7edde21
Akademický článek
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Autor:
Agata Grzejdziak, Witold Brniak, Olaf Lengier, Justyna Anna Żarek, Dziyana Hliabovich, Aleksander Mendyk
Publikováno v:
Pharmaceutics, Vol 16, Iss 9, p 1153 (2024)
Minitablets have been extensively studied in recent years as a convenient pediatric form because they allow successful administration even in very young children. Their advantages include easy dose adjustment by multiplication of single units as well
Externí odkaz:
https://doaj.org/article/503103b32ce24a7e97e638cb14a15092
Autor:
O. D. Ostroumova, M. L. Maksimov, M. V. Zamergrad, V. A. Parfenov, E. K. Zaharova, A. L. Vladykin, A. A. Globenko, A. V. Kapashin, K. A. Ishchenko
Publikováno v:
Неврология, нейропсихиатрия, психосоматика, Vol 15, Iss 4, Pp 53-65 (2023)
Objective: to evaluate the pharmacokinetic parameters, safety and tolerability of Vespireit® (INN buspirone), prolonged-release tablets, 15 mg (JSC “Valenta Pharm”, Russia), which is being developed as a drug for the treatment of functional vert
Externí odkaz:
https://doaj.org/article/1c0a0f3c1a3b413a9a5f047078d4eaf3
Publikováno v:
Неврология, нейропсихиатрия, психосоматика, Vol 15, Iss 3, Pp 68-75 (2023)
The prolonged release tablets form of alimemazine is seen as a promising agent for the long-term treatment of generalized anxiety disorder (GAD).Objective: to investigate the efficacy and safety of therapy with alimemazine (Teraligen® retard, prolon
Externí odkaz:
https://doaj.org/article/d5611dce904048eba2fce8a56cf6cd99
Autor:
Bernadette Hard, Mohan DeSilva
Publikováno v:
Pilot and Feasibility Studies, Vol 9, Iss 1, Pp 1-10 (2023)
Abstract Background Effective opioid agonist therapy (OAT) depends on good patient adherence. However, the daily, supervised administration of standard OAT represents a significant burden to patients and often drives poor adherence. Prolonged-release
Externí odkaz:
https://doaj.org/article/969e581ba4b5490d9fe260eb44148ae1
Publikováno v:
Mìžnarodnij Endokrinologìčnij Žurnal, Vol 19, Iss 2, Pp 143-148 (2023)
Diabetes mellitus (DM) and its complications are one of the leading causes of death worldwide, with approximately 700 million people expected to suffer from DM by 2045, according to the International Diabetes Federation. DM is a progressive, chronic
Externí odkaz:
https://doaj.org/article/072d4761720c4dcd87dc9fe90ab5443a