Zobrazeno 1 - 3
of 3
pro vyhledávání: '"proline mimic"'
Autor:
Alessandro Tossi, Petia Genova, Federico Berti, Pietro Campaner, Fabio Benedetti, Francesca Dinon, Anton Hinkov, Sara Budal, Radka Argirova, Vasil Atanassov
Publikováno v:
Journal of Medicinal Chemistry. 55:3900-3910
Peptidomimetic inhibitors of HIV-1 PR are still a key resource in the fight against AIDS. Here we describe the synthesis and biological activity of HIV-1 PR inhibitors based on four novel dihydroxyethylene isosteres of the Phe-Pro and Pro- Pro dipept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::772e2e15d6980b4454241b94655d4a6f
https://doi.org/10.1021/jm3001136
https://doi.org/10.1021/jm3001136
Autor:
Bäck, Marcus
This thesis describes the design, synthesis and structure-activity relationships analysis of potential inhibitors targeting the hepatitis C virus (HCV) NS3 protease. Also discussed is the disease caused by HCV infection and the class of enzymes known
Externí odkaz:
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-8395
