Zobrazeno 1 - 10
of 112
pro vyhledávání: '"programmed death-ligand 2"'
Autor:
Parisa Shiri Aghbash, Faezeh Mehdizadeh, Ghazal Pourbeiragh, Yalda Yazdani, Hossein Bannazadeh Baghi, Abolfazl Jafari Sales, Mehrdad Pashazadeh, Parisa Kangari
Publikováno v:
Advances in Cancer Biology - Metastasis, Vol 11, Iss , Pp 100125- (2024)
Because of emerging opportunities for cancer immunotherapy, the capacity to suppress the immune system in order to cure and eradicate cancer is currently a topic of intense study. When the bone marrow microenvironment is exposed to immune suppression
Externí odkaz:
https://doaj.org/article/4801590dc96d47e9b323e13f9f87b205
Autor:
K. V. Nikulnikov, V. A. Bogdanova, L. V. Spirina, S. Yu. Chizhevskaya, I. V. Kondakova, E. L. Choynzonov, V. I. Chernov
Publikováno v:
Успехи молекулярной онкологии, Vol 11, Iss 1, Pp 46-54 (2024)
Introduction. Melanoma is the most dangerous neoplasm of the skin, characterized by a malignant and aggressive course. Transcriptional and growth factors, components of the AKT/mTOR signaling pathway, receptors and ligands of programmed cell death ar
Externí odkaz:
https://doaj.org/article/6b95f20c2dfc4abd81e7719a76815f51
Autor:
Suxia Geng, Ruohao Xu, Xin Huang, Minming Li, Chengxin Deng, Peilong Lai, Yulian Wang, Ping Wu, Xiaomei Chen, Jianyu Weng, Xin Du
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Hypomethylating agents (HMAs) are widely used in patients with higher-risk MDS not eligible for stem cell transplantation. However, the general response rate by HMAs is lesser than 50% in MDS patients, while the relapse rate is high. Emerging evidenc
Externí odkaz:
https://doaj.org/article/c4f90879820d4bb0a080d4069b6b6fc0
Publikováno v:
Tropical Medicine and Infectious Disease, Vol 8, Iss 1, p 46 (2023)
Capillaria hepatica is a seriously neglected zoonotic parasite, which infects the liver of mammalian hosts, causing fibrosis or even hepatic failure. At present, the immune responses elicited by C. hepatica are not fully understood, and the role(s) o
Externí odkaz:
https://doaj.org/article/726d21195c9748deb0a1f6f1b1c17a55
Autor:
Oliviero Marinelli, Daniela Annibali, Maria Beatrice Morelli, Laura Zeppa, Sandra Tuyaerts, Cristina Aguzzi, Consuelo Amantini, Federica Maggi, Benedetta Ferretti, Giorgio Santoni, Frédéric Amant, Massimo Nabissi
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
In cancer, upregulation of coinhibitory B7 ligands has been associated with immune evasion. So far, anti-programmed death-1 (PD-1) and anti-PD-ligand 1 (PD-L1) antibodies have been used in immuno-oncology, with promising outcomes; however, it is stil
Externí odkaz:
https://doaj.org/article/616ff2258d4646bab4df0d28403c334d
Akademický článek
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Publikováno v:
Journal of Pathology and Translational Medicine, Vol 51, Iss 2, Pp 152-158 (2017)
Background Glucose transporter type 1 (GLUT1) expression is linked to glucose metabolism and tissue hypoxia. A recent study reported that GLUT1 was significantly associated with programmed death ligand 1 (PD-L1) as a therapeutic target in relapsed or
Externí odkaz:
https://doaj.org/article/6740617262ef4ca1a77a7211537218d2
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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Autor:
Felipe von Glehn, Nathalie Pochet, Bibek Thapa, Radhika Raheja, Maria A. Mazzola, Sushrut Jangi, Vanessa Beynon, Junning Huang, Alessandro S. Farias, Anu Paul, Leonilda M. B. Santos, Roopali Gandhi, Gopal Murugaiyan, Howard L. Weiner, Clare M. Baecher-Allan
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 9; Pages: 8000
The purpose of this study was to examine whether myeloid dendritic cells (mDCs) from patients with multiple sclerosis (MS) and healthy controls (HCs) become similarly tolerogenic when exposed to IL-27 as this may represent a potential mechanism of au
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a1683e796f6efab8155693bae2386ba
Autor:
Julie Mielle, Rachel Audo, Michael Hahne, Laurence Macia, Bernard Combe, Jacques Morel, Claire Daien
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Despite growing evidence highlighting the relevance of increasing IL-10-producing B cells (B10+cells) in autoimmune diseases, their functions in patients are still unknown. The aim of this study was to evaluate the functions of CpG-induced B10+ cells
Externí odkaz:
https://doaj.org/article/ec0275e74e274f349adf3b3f623d914d