Zobrazeno 1 - 10
of 3 013
pro vyhledávání: '"programmed death‐1"'
Publikováno v:
Zhongguo Linchuang Yixue, Vol 31, Iss 5, Pp 757-764 (2024)
ObjectiveTo explore the impact of sex on the efficacy of first-line programmed death-1 (PD-1) blockade plus chemotherapy in patients with advanced lung adenocarcinoma and its potential biological mechanisms. MethodsThe clinical and pathological chara
Externí odkaz:
https://doaj.org/article/34d31f9005d04fa1bc4eab138541de5f
Autor:
Masato Karayama, Naoki Inui, Yusuke Inoue, Hideki Yasui, Hironao Hozumi, Yuzo Suzuki, Kazuki Furuhashi, Tomoyuki Fujisawa, Noriyuki Enomoto, Kazuhiro Asada, Koji Nishimoto, Masato Fujii, Takashi Matsui, Shun Matsuura, Dai Hashimoto, Mikio Toyoshima, Masaki Ikeda, Hiroyuki Matsuda, Nao Inami, Yusuke Kaida, Satoshi Funayama, Shintaro Ichikawa, Satoshi Goshima, Takafumi Suda
Publikováno v:
BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Immune-related pneumonitis (irP) is one of the most important immune-related adverse events caused by immune checkpoint inhibitors (ICIs). After corticosteroid therapy irP frequently relapses, which can interfere with cancer thera
Externí odkaz:
https://doaj.org/article/bb069103ab2445de9eae9f506ee87ea8
Autor:
Huan Zhang, Daoyuan Song, Qiulin Luo, Jiangkun Yu, Yingpu Wei, Di Chen, Guangjuan Wu, Zhi Zhang, Zhao Li, Hongchao Jiang, Jingquan Gan, Deyao Deng, Hui Li, Wenli Yuan
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
IntroductionCandida albicans gastrointestinal (GI) colonization is crucial for the onset of invasive disease. This research encompassed 31 patients diagnosed with Candida spp. bloodstream infections during their admission to a university hospital in
Externí odkaz:
https://doaj.org/article/20a91cb7c1aa42a4abc2572f4cd6ebf3
Autor:
Parisa Shiri Aghbash, Faezeh Mehdizadeh, Ghazal Pourbeiragh, Yalda Yazdani, Hossein Bannazadeh Baghi, Abolfazl Jafari Sales, Mehrdad Pashazadeh, Parisa Kangari
Publikováno v:
Advances in Cancer Biology - Metastasis, Vol 11, Iss , Pp 100125- (2024)
Because of emerging opportunities for cancer immunotherapy, the capacity to suppress the immune system in order to cure and eradicate cancer is currently a topic of intense study. When the bone marrow microenvironment is exposed to immune suppression
Externí odkaz:
https://doaj.org/article/4801590dc96d47e9b323e13f9f87b205
Autor:
WANG Fei, LIU Pei, HU Nan
Publikováno v:
Zhongguo aizheng zazhi, Vol 34, Iss 5, Pp 493-500 (2024)
Background and purpose: Second-line chemotherapy is not effective in the treatment of gastric cancer. Bevacizumab is a molecularly targeted anticancer drug, and sindilizumab is a domestic programmed death-1 (PD-1) inhibitor. The combination of the tw
Externí odkaz:
https://doaj.org/article/84f263a5c5874164adebd1016d696e5c
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Sarcopenia has been associated with higher toxicity induced by anti-cancer treatments and shorter survival in patients with squamous cell lung carcinoma (SqCLC). Over the past few decades, immune checkpoint inhibitors (ICIs) significantly im
Externí odkaz:
https://doaj.org/article/cff75045772b467eaee5b9a323d8d9d9
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
PurposeTo assess the potential added value of the lung immune prognostic index (LIPI) in patients with small cell lung cancer (SCLC), treated with programmed death-ligand 1 (PD-L1)/programmed death-1 (PD-1) inhibitors, who lived in the Chinese alpine
Externí odkaz:
https://doaj.org/article/bbe233e33f694ba3b1f2c43e1eb8026a
Autor:
Yongmei Wang, Yi-Li Chen, Hui Xu, Gul E. Rana, Xiaorong Tan, Mengying He, Qingqing Jing, Qi Wang, Guifeng Wang, Zuoquan Xie, Chunhe Wang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionHumanization is typically adopted to reduce the immunogenicity of murine antibodies generated by hybridoma technology when used in humans.MethodsTwo different strategies of antibody humanization are popularly employed, including “comple
Externí odkaz:
https://doaj.org/article/4de509a4348b4b1e9ee265d2f6b70fc5
Autor:
Yong Li, Jinpeng Huang, Xian Chen, Yongsong Ye, Xiaohua Du, Ioannis A. Voutsadakis, Mahesh Seetharam, Haibo Zhang, Min Lu
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundUndifferentiated small round-cell sarcomas (uSRCSs) are a subgroup of sarcomas that are difficult to diagnose. Some uSRCSs have specific gene re-arrangements, but others do not. Currently, there is no specific treatments for advanced uSRCSs
Externí odkaz:
https://doaj.org/article/e3a3030071e146cb882b09f6287bae72
Autor:
Li, Yang a, c, Zhao, Zhibo a, He, Linru a, Liang, Yue a, Liu, Meng a, Dong, Meiqi a, Li, Zehao a, Xu, Bin a, Zhang, Zecai a, Zhou, Yulong a, Liu, Yu a, c, Zhu, Zhanbo a, b, c, ⁎, Zhao, Jianjun a, b, c, ⁎
Publikováno v:
In Veterinary Microbiology January 2025 300