Zobrazeno 1 - 10
of 401
pro vyhledávání: '"prognosis signature"'
Autor:
Ling Lu, Huaguo Feng, Guohua Dai, Shuangquan Liu, Yi Feng, Haoyang Tan, Xian Zhang, Guoqing Hong, Xing Lai
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Cancer-associated fibroblasts (CAFs), integral components of the tumor microenvironment, play a pivotal role in tumor proliferation, metastasis, and clinical outcomes. However, its specific roles in Kidney Renal Clear Cell Carcinoma (KIRC) r
Externí odkaz:
https://doaj.org/article/ba2209d2b9d94857b057a58162c6fa37
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Uveal melanoma (UVM) is the most common primary tumor in adult human eyes. Costimulatory molecules (CMs) are important in maintaining T cell biological functions and regulating immune responses. To investigate the role of CMs in UVM and expl
Externí odkaz:
https://doaj.org/article/a935dca1d5114a0c82a8767d7676222a
A novel prognostic signature and therapy guidance for hepatocellular carcinoma based on STEAP family
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-12 (2024)
Abstract Background The six-transmembrane epithelial antigen of prostate (STEAP) family members are known to be involved in various tumor-related biological processes and showed its huge potential role in tumor immunotherapy. Methods Biological diffe
Externí odkaz:
https://doaj.org/article/fc363b005062464b815cd7656061af49
Autor:
Guoqing Ouyang, Qiuyun Li, Yangnian Wei, Wenbin Dai, Haojian Deng, Youli Liu, Jiaguang Li, Mingjuan Li, Shunwen Luo, Shuang Li, Yunying Liang, Guandong Pan, Jianqing Yang, Tao Gan
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundHepatocellular carcinoma (HCC) is one of the most lethal malignancies worldwide. PANoptosis is a recently unveiled programmed cell death pathway, Nonetheless, the precise implications of PANoptosis within the context of HCC remain incomplet
Externí odkaz:
https://doaj.org/article/ba629dc827584038ae16c83c95a07c8d
Autor:
Xiang-Xu Wang, Yun-Peng Liu, Yajie Lu, Li-Hong Wu, Jing-Yi Ren, Hongchen Ji, Xiaowen Wang, Hong-Mei Zhang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundThe tertiary lymphatic structure (TLS) is an important component of the tumor immune microenvironment and has important significance in patient prognosis and response to immune therapy. However, the underlying mechanism of TLS in soft tissu
Externí odkaz:
https://doaj.org/article/5a450bf2b65e41f18207e58ca33e418b
Autor:
Jiani Yang, Chao Wang, Yue Zhang, Shanshan Cheng, Meixuan Wu, Sijia Gu, Shilin Xu, Yongsong Wu, Jindan Sheng, Dominic Chih-Cheng Voon, Yu Wang
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-20 (2023)
Abstract Ovarian cancer (OV) is the most lethal gynecological malignancies worldwide. The coagulation cascade could induce tumor cell infiltration and contribute to OV progression. However, coagulation-related gene (CRG) signature for OV prognosis ha
Externí odkaz:
https://doaj.org/article/795b2ec75dc449909203ae8024b3e111
Publikováno v:
Heliyon, Vol 10, Iss 6, Pp e28156- (2024)
Background: Liver hepatocellular carcinoma (LIHC) is a solid primary malignancy with poor prognosis. This study discovered key prognostic genes based on T cell exhaustion and used them to develop a prognostic prediction model for LIHC. Methods: Singl
Externí odkaz:
https://doaj.org/article/28a1b17adcab4092a6dc9cff05c4c774
Publikováno v:
Heliyon, Vol 10, Iss 3, Pp e25573- (2024)
Background: Bladder cancer (BLCA) is prone to metastasis and has poor prognosis with unsatisfactory treatment responsiveness. Disulfidptosis is a recently discovered, novel mode of cell death that is closely associated with human cancers. However, a
Externí odkaz:
https://doaj.org/article/be4f1f99fed14d2592c6d751f04a98bd
Publikováno v:
Annals of Medicine, Vol 55, Iss 2 (2023)
AbstractBackground Neutrophil extracellular traps (NETs) could entrap tumour cells and promote their dissemination and metastasis. Further analysis of NETs-related molecules is expected to provide a new strategy for prognosis prediction and treatment
Externí odkaz:
https://doaj.org/article/568e5ed090124bf883daedf8c8510b08
Autor:
Nana Wang, Xiaoran Bai, Xinlu Wang, Dongmei Wang, Guangxin Ma, Fan Zhang, Jingjing Ye, Fei Lu, Chunyan Ji
Publikováno v:
Current Oncology, Vol 30, Iss 2, Pp 2524-2542 (2023)
Acute myeloid leukaemia (AML) is the most common acute leukaemia in adults, with an unfavourable outcome and a high rate of recurrence due to its heterogeneity. Dysregulation of fatty acid metabolism plays a crucial role in the development of several
Externí odkaz:
https://doaj.org/article/5723ef69ebb74e84a8f2b6d5be16e54a