Epigenetic Regulation Interplays with Endometriosis Pathogenesis in Low-Birth-Weight Patients via the Progesterone Receptor B–VEGF-DNMT1 Axis

Autor: Arief Setiawan, Ruswana Anwar, Mas Rizky Anggun Adipurna Syamsunarno, Johanes Cornelius Mose, Budi Santoso, Ani Melani Maskoen, Wiryawan Permadi, Budi Setiabudiawan, Meita Dhamayanti, Yudi Mulyana Hidayat

Publikováno v: Diagnostics, Vol 13, Iss 12, p 2085 (2023)

Background: Low birth weight (LBW) is a risk factor associated with endometriosis. Our study aimed to analyze the risk of endometriosis in women with a LBW history and the relationships of progesterone receptor B (PR-B) gene promoter methylation, DNA

Externí odkaz: https://doaj.org/article/e809d588b1784f38b90f664c2f4819ec

Epigenetic Regulation Interplays with Endometriosis Pathogenesis in Low-Birth-Weight Patients via the Progesterone Receptor B–VEGF-DNMT1 Axis

Autor: Hidayat, Arief Setiawan, Ruswana Anwar, Mas Rizky Anggun Adipurna Syamsunarno, Johanes Cornelius Mose, Budi Santoso, Ani Melani Maskoen, Wiryawan Permadi, Budi Setiabudiawan, Meita Dhamayanti, Yudi Mulyana

Publikováno v: Diagnostics; Volume 13; Issue 12; Pages: 2085

Background: Low birth weight (LBW) is a risk factor associated with endometriosis. Our study aimed to analyze the risk of endometriosis in women with a LBW history and the relationships of progesterone receptor B (PR-B) gene promoter methylation, DNA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=multidiscipl::45d6c7a136b034b2df4ed874fcbb96ec

Highly Expressed Progesterone Receptor B Isoform Increases Platinum Sensitivity and Survival of Ovarian High-Grade Serous Carcinoma

Autor: Kuo-Chung Lan, Yu-Che Ou, Hung-Chun Fu, I-Chieh Chuang, Hao Lin, Chen-Hsuan Wu, Hong-Yo Kang

Publikováno v: Cancers
Volume 13
Issue 21
Cancers, Vol 13, Iss 5578, p 5578 (2021)

Simple Summary Ovarian high-grade serous carcinoma is the deadliest ovarian cancer. Cancer cells develop resistance to anti-cancer regimens leading to poor prognosis. Previous studies showed that the progesterone receptor was associated with better r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::760613b274470503e628e76122e93dd2
https://pubmed.ncbi.nlm.nih.gov/34771742

Differential expression of progesterone receptor isoforms related to PGR +331g/a polymorphism in endometriosis: A case-control study

Autor: Maryam Shahhoseini, Reza Aflatoonian, Azadeh Ghaheri, Parvaneh Afsharian, Sepideh Mousazadeh

Publikováno v: International Journal of Reproductive BioMedicine, Vol 17, Pp 185-194 (2019)
International Journal of Reproductive Biomedicine
International Journal of Reproductive BioMedicine, Vol 17, Iss 3, Pp 185-194 (2019)
International Journal of Reproductive BioMedicine, Vol 17, Pp 1-10 (2019)

Background Endometriosis are defined as a progesterone-resistance disease. Two progesterone receptor (PR) isoforms, namely PR-A and PR-B, mediate the special effects of progesterone. One of the most effective polymorphism in the promoter region of PG

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b4640147c861811d3a6cdcc57481ad8
https://doaj.org/article/ba8eb73a276c4ec082d1a6e0b31ce41c

Progesterone Receptor B (PGR-B) Is Partially Methylated in Eutopic Endometrium From Infertile Women With Endometriosis

Autor: Carlos Valério Rocha-Junior, Juliana Meola, Michele Gomes Da Broi, Cristiana Libardi Miranda-Furtado, Rui Alberto Ferriani, Paula Andrea de Albuquerque Salles Navarro

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Endometriosis is frequently related to infertility and little is known about the mechanisms underlying this association. Some studies point to an endometrial factor involved in this condition, which could compromise embryo implantation. Progesterone

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecc5f753267e72368ca85a2df94255e0
https://doi.org/10.1177/1933719119828078