Zobrazeno 1 - 10
of 29 381
pro vyhledávání: '"progesterone receptor"'
Publikováno v:
Animal Bioscience, Vol 37, Iss 8, Pp 1377-1386 (2024)
Objective Embryonic interferon-tau (IFNT) and progesterone affect expression of interferon-stimulated genes (ISGs), progesterone receptor (PGR) and progesterone-induced blocking factor (PIBF) in the ovine thyroid. Methods Thyroids of ewes were sample
Externí odkaz:
https://doaj.org/article/df61e9d49aa341c5836b7fd4564edbb2
Autor:
Hugh S. Taylor, M.D., Liying Dong, M.D., Ph.D., Johanna Haikonen, M.D., Peter Oppelt, M.D., Karl Tamussino, M.D., Rene Wenzl, M.D., Ph.D., Thomas Faustmann, M.D., Esther Groettrup-Wolfers, M.D., Ph.D., Xiaowei Ren, Ph.D., Christian Seitz, M.D., Ph.D.
Publikováno v:
F&S Reports, Vol 5, Iss 2, Pp 189-196 (2024)
Objective: To evaluate the efficacy and safety of 2 doses of vilaprisan vs. placebo in participants with symptomatic endometriosis. Design: Multicenter, randomized, double-blind, placebo-controlled, parallel-group phase 2b trial (NCT03573336). The in
Externí odkaz:
https://doaj.org/article/d8f6b31dc0ed4dc1a5fa02650f0442ca
Publikováno v:
Journal of Xenobiotics, Vol 14, Iss 2, Pp 575-603 (2024)
Progesterone receptor membrane component 1 (PGRMC1) is one of few proteins that have been recently described as direct modulators of the activity of human cytochrome P450 enzymes (CYP)s. These enzymes form a superfamily of membrane-bound hemoproteins
Externí odkaz:
https://doaj.org/article/c881402b56ee4ab29ec0f1303888a296
Publikováno v:
International Journal of General Medicine, Vol Volume 17, Pp 1677-1694 (2024)
Lu Liu,1 Shuang Yuan,1 Shouheng Yao,1 Wenjiao Cao,1,2 Lihua Wang1 1The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200030, People’s Republic of China; 2Shanghai Key Laborator
Externí odkaz:
https://doaj.org/article/779ac0a4166d4bbd8477c4e1fe84f9c2
Autor:
Haimeng Shi, Jian Li, Tong Yan, Ling Zhou, Yu Zhu, Feifei Guo, Sihui Yang, Xiangyi Kong, Huaijun Zhou
Publikováno v:
Translational Oncology, Vol 47, Iss , Pp 102041- (2024)
Objective: This study aimed to clarify the mechanism by which Krüppel-like factor 12 (KLF12) affects progesterone sensitivity in endometrial cancer (EC) through the progesterone receptor PGR signaling pathway. Methods: The relationship of KLF12 with
Externí odkaz:
https://doaj.org/article/10b40975fe4144feae8f6a198dad1171
Autor:
Chung-Che Tsai, Yung-Ning Yang, Kuan Wang, Yu-Chun E. Chen, Yi-Fong Chen, Jen-Chang Yang, Zi-Lin Li, Haw-Ming Huang, Jens Z. Pedersen, Sandra Incerpi, Sheng-Yang Lee, Hung-Yun Lin, Jaqueline Whang-Peng
Publikováno v:
Heliyon, Vol 10, Iss 13, Pp e34006- (2024)
Progesterone (P4) plays a pivotal role in regulating the cancer progression of various types, including breast cancer, primarily through its interaction with the P4 receptor (PR). In PR-negative breast cancer cells, P4 appears to function in mediatin
Externí odkaz:
https://doaj.org/article/7e3013834876452d9bf07b1276ce3013
Autor:
Md. Forhad Hossain, Shakhawat Hossain, Md. Maisum Sarwar Jyoti, Yuki Omori, Saokat Ahamed, Toshinobu Tokumoto
Publikováno v:
Biochemistry and Biophysics Reports, Vol 38, Iss , Pp 101691- (2024)
Previously, we established a homogeneous assay for membrane progesterone receptor alpha (mPRα) ligands by conjugating semiconductor nanoparticles known as graphene quantum dots (GQDs) to mPRα. When mixed with a progesterone-BSA-fluorescein isothioc
Externí odkaz:
https://doaj.org/article/b4ca992092e242aaa29aa5b534fabcda
Autor:
Hailun Liu, André Franken, Alexandra P. Bielfeld, Tanja Fehm, Dieter Niederacher, Zhongping Cheng, Hans Neubauer, Nadia Stamm
Publikováno v:
Reproductive Biology and Endocrinology, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Decidualization of endometrial cells is the prerequisite for embryo implantation and subsequent placenta formation and is induced by rising progesterone levels following ovulation. One of the hormone receptors contributing to endo
Externí odkaz:
https://doaj.org/article/1dbb22213ddc43528911c90156f44bbb
Autor:
He Dou, Fucheng Li, Youyu Wang, Xingyan Chen, Pingyang Yu, Siyuan Jia, Yuling Ba, Danli Luo, Tian Gao, Zhaoting Li, Min Xiao
Publikováno v:
Diagnostic Pathology, Vol 19, Iss 1, Pp 1-18 (2024)
Abstract Purpose The status of hormone receptors (HR) is an independent factor affecting survival and chemotherapy sensitivity in breast cancer (BC) patients, with estrogen receptor (ER) and progesterone receptor (PR) having the most significant effe
Externí odkaz:
https://doaj.org/article/437bc97cfc3c4b389bf4b7152695cfd1