The role of endogenous versus exogenous sources in the exposome of putative genotoxins and consequences for risk assessment

Autor: Rietjens, Ivonne M C M, Arand, Michael, Bolt, Hermann M, Bourdoux, Siméon, Hartwig, Andrea, Hinrichsen, Nils, Kalisch, Christine, Mally, Angela, Pellegrino, Gloria, Ribera, Daniel, Thatcher, Natalie, Eisenbrand, Gerhard

Publikováno v: Archives of Toxicology, 96 (5), 1297–1352
Archives of Toxicology, 96(5), 1297-1352
Archives of toxicology, 96(5):1297-1352
Archives of Toxicology 96 (2022) 5

The “totality” of the human exposure is conceived to encompass life-associated endogenous and exogenous aggregate exposures. Process-related contaminants (PRCs) are not only formed in foods by heat processing, but also occur endogenously in the o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::831402af5cdde588a7d3660505cba4af
https://doi.org/10.1007/s00204-022-03242-0

Exposure assessment of process-related contaminants in food by biomarker monitoring

Autor: Helmut Günther, James A. Swenberg, Gabriele Scholz, Hiroshi Honda, Paul Hanlon, Gerhard Eisenbrand, Angela Mally, Justin G. Teeguarden, Pierre Dussort, Ivonne M.C.M. Rietjens, Albrecht Seidel, Sue O’Hagan

Publikováno v: Archives of Toxicology 92 (2018) 1
Archives of Toxicology, 92(1), 15-40

Exposure assessment is a fundamental part of the risk assessment paradigm, but can often present a number of challenges and uncertainties. This is especially the case for process contaminants formed during the processing, e.g. heating of food, since

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eda3aff9b4b08c9e302cc6e6da78ae38
https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-226268

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