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Akademický článek

LAG3 is not expressed in human and murine neurons and does not modulate α‐synucleinopathies

Publikováno v: EMBO Molecular Medicine, Vol 13, Iss 9, Pp 1-20 (2021)

Abstract While the initial pathology of Parkinson’s disease and other α‐synucleinopathies is often confined to circumscribed brain regions, it can spread and progressively affect adjacent and distant brain locales. This process may be controlled

Externí odkaz: https://doaj.org/article/7994f076bf964ea9bf26f7f4ba6a434a

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LAG3 is not expressed in human and murine neurons and does not modulate α‐synucleinopathies

Publikováno v: EMBO Molecular Medicine
EMBO Molecular Medicine, Wiley Open Access, 2021, pp.e14745. ⟨10.15252/emmm.202114745⟩
EMBO Molecular Medicine, 2021, pp.e14745. ⟨10.15252/emmm.202114745⟩
EMBO Molecular Medicine, Vol 13, Iss 9, Pp n/a-n/a (2021)
EMBO molecular medicine 13(9), e14745 (2021). doi:10.15252/emmm.202114745

Funder: University of Zurich and University Hospital of Zurich
Funder: NOMIS Stiftung (NOMIS Foundation); Id: http://dx.doi.org/10.13039/501100008483
Funder: Forschungskredit University of Zurich
While the initial pathology of Parkinso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6f25fe5c0dcaf700f2efab607e761a3

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Akademický článek

Histochemical approaches to assess cell-to-cell transmission of misfolded proteins in neurodegenerative diseases

Autor: G. Natale, E. Pompili, F. Biagioni, S. Paparelli, P. Lenzi, F. Fornai

Publikováno v: European Journal of Histochemistry, Vol 57, Iss 1, Pp e5-e5 (2013)

Formation, aggregation and transmission of abnormal proteins are common features in neurodegenerative disorders including Parkinson’s disease, Alzheimer’s disease, amyotrophic lateral sclerosis, and Huntington’s disease. The mechanisms underlyi

Externí odkaz: https://doaj.org/article/14ae876ab5314b4690b0a8013936279b

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Prion-like proteins and their computational identification in proteomes

Autor: Batlle C, Iglesias V, Navarro S, Ventura S

Publikováno v: EXPERT REV PROTEOMIC
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
EXPERT REVIEW OF PROTEOMICS
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname

The aberrant or misfolded forms of the prion protein have been described as the causative agents of rare transmissible spongiform encephalopathies. In addition, proteins associated with frequently occurring neurodegenerative disorders, such as Alzhei

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0986c02b5fa571a29b111be013e365a4
http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=18913

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Rapamycin induces neuronal differentiation and decreases prion-like proteins in human glioblastoma cell cultures

Autor: Ferrucci, Michela, Lazzeri, Gloria, Falleni, Alessandra, Guagnozzi, Mariangela, Biagioni, Francesca, Fucile, Sergio, Limatola, Cristina, Esposito, Vincenzo, Paparelli, Antonio

Glioblastoma (GB, grade IV astrocytoma) is highly proliferating, infiltrating, and relapsing. So far, no therapy cures the disease and on average lethality occurs within 2 years from diagnosis. Despite the intimate molecular mechanisms of GB remain u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6ee5da77e060e5b2bf65aab6c5be73e

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Neuroanatomy as a guide to understand disease spreading

Autor: Ferrucci, Michela, Fulceri, Federica, Gesi, Marco, Natale, Gianfranco, Ruffoli, Riccardo, Soldani, Paola, Fornai, Francesco

The classic region-specific characterization of various neurodegenerative disorders and acute neurological insults has been challenged by recent studies showing multiple brain areas and peripheral sites in addition to those specifically described as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27a4153c4bb44a14c7d1b167bf138423
http://hdl.handle.net/11568/678264

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Prions, prionoids and pathogenic proteins in Alzheimer disease

Autor: Karen H. Ashe, Adriano Aguzzi

Publikováno v: Prion

Like patients with prion disease, Alzheimer patients suffer from a fatal, progressive form of dementia. There is growing evidence that amyloid-β (Aβ) aggregates may be transmissible similar to prions, at least under extreme experimental conditions.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1210ea6208154c225391233b2c5988c7
https://pubmed.ncbi.nlm.nih.gov/23208281

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