Zobrazeno 1 - 10
of 2 193
pro vyhledávání: '"prime–boost"'
Autor:
Qing Lei, Hui Fu, Zongjie Yao, Zijie Zhou, Yueqing Wang, Xiaosong Lin, Yin Yuan, Qi Ouyang, Xinyue Xu, Jinge Cao, Mengze Gan, Xionglin Fan
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background The Bacillus Calmette-Guérin (BCG) vaccine, currently the sole authorized vaccine against tuberculosis (TB), demonstrates limited effectiveness in safeguarding adolescents and adults from active TB, even when administered as a bo
Externí odkaz:
https://doaj.org/article/c83eb74d14ef4f3fbf48bf754e04d77f
Autor:
Gabiria Pastore, Jacopo Polvere, Fabio Fiorino, Simone Lucchesi, Giorgio Montesi, Ilaria Rancan, Sara Zirpoli, Arianna Lippi, Miriam Durante, Massimiliano Fabbiani, Mario Tumbarello, Francesca Montagnani, Donata Medaglini, Annalisa Ciabattini
Publikováno v:
Expert Review of Vaccines, Vol 23, Iss 1, Pp 432-444 (2024)
Background Heterologous prime-boost schedules have been employed in SARS-CoV-2 vaccination, yet additional data on immunogenicity and effectiveness are still needed.Research design and methods Here, we measured the immunogenicity and effectiveness in
Externí odkaz:
https://doaj.org/article/57414c1aeb95453cac2578ec49079d8f
Autor:
Antonia Radaelli, Carlo Zanotto, Chiara Brambilla, Tommaso Adami, Francesca Paolini, Aldo Venuti, Adriana Manuka, Irsida Mehmeti, Carlo De Giuli Morghen
Publikováno v:
Virology Journal, Vol 21, Iss 1, Pp 1-12 (2024)
Highlights Recombinant avipoxviruses as putative recombinant vaccines against MPXV. Different prime–boost regimens to improve immunization against orthopoxviruses. Mucosal and intramuscular immunization to enhance the humoral and neutralizing immun
Externí odkaz:
https://doaj.org/article/1c1531897baa4c83a54eca993ea56772
Autor:
Li D, Bian L, Cui L, Zhou J, Li G, Zhao X, Xing L, Cui J, Sun B, Jiang C, Kong W, Zhang Y, Chen Y
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 8029-8042 (2024)
Dongdong Li,1 Lijun Bian,1 Lili Cui,2 Jingying Zhou,1 Gaotian Li,1 Xiaoyan Zhao,1 Liao Xing,1 Jiaxing Cui,1 Bo Sun,1 Chunlai Jiang,1,3,4 Wei Kong,1,3,4 Yong Zhang,1,3,4 Yan Chen1,3,4 1National Engineering Laboratory for AIDS Vaccine, School of Life S
Externí odkaz:
https://doaj.org/article/07528551113b4c769cc33f13f20543bb
Autor:
Hiroki Uchiyama, Toshifumi Kudo, Takehiro Yamaguchi, Nozomu Obana, Kenji Watanabe, Kimihiro Abe, Hidetaka Miyazaki, Masanori Toyofuku, Nobuhiko Nomura, Yukihiro Akeda, Ryoma Nakao
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)
ABSTRACTThere is a growing interest in development of novel vaccines against respiratory tract infections, due to COVID-19 pandemic. Here, we examined mucosal adjuvanticity and the mucosal booster effect of membrane vesicles (MVs) of a novel probioti
Externí odkaz:
https://doaj.org/article/f9ac0a5cea9a47029ede47ea185d23ea
Autor:
Raúl E. Molina, Alberto Osorio, Manuel Flores-Concha, Leonardo A. Gómez, Ilse Alvarado, Italo Ferrari, Angel Oñate
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe development of effective vaccines against Brucella abortus is critical due to its significant impact on human and animal health. The objective of this study was to design and evaluate in silico and in vivo a multivalent vaccine based
Externí odkaz:
https://doaj.org/article/f6e1d547e6a1412ea2392d4da9948698
Autor:
Juan Liu, Huafeng Han, Binbin Yang, Naifang Zhang, Jing Li, Xicheng Chen, Jie Wu, Yingying Zhao, Yongsheng Yang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
With the rapid global spread of COVID-19 and the continuous emergence of variants, there is an urgent need to develop safe and effective vaccines. Here, we developed a novel mRNA vaccine, HC009, based on new formulation by the QTsome delivery platfor
Externí odkaz:
https://doaj.org/article/df3d7fd7836f42f6a0614cad492db648
Autor:
Muriel Metko, Jason Tonne, Alexa Veliz Rios, Jill Thompson, Haley Mudrick, David Masopust, Rosa Maria Diaz, Michael A. Barry, Richard G. Vile
Publikováno v:
Vaccines, Vol 12, Iss 10, p 1191 (2024)
Background: Long-lived, re-activatable immunity to SARS-CoV-2 and its emerging variants will rely on T cells recognizing conserved regions of viral proteins across strains. Heterologous prime–boost regimens can elicit elevated levels of circulating
Externí odkaz:
https://doaj.org/article/d98810f9d5c34f26ac87a699cbde1ffe
Sex differences in immune protection in mice conferred by heterologous vaccines for pneumonic plague
Autor:
Michael L. Davies, Sergei S. Biryukov, Nathaniel O. Rill, Christopher P. Klimko, Melissa Hunter, Jennifer L. Dankmeyer, Jeremy A. Miller, Jennifer L. Shoe, Kevin D. Mlynek, Yuli Talyansky, Ronald G. Toothman, Ju Qiu, Joel A. Bozue, Christopher K. Cote
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundYersinia pestis is the etiological agent of plague, which can manifest as bubonic, septicemic, and/or pneumonic disease. Plague is a severe and rapidly progressing illness that can only be successfully treated with antibiotics initiated ear
Externí odkaz:
https://doaj.org/article/32e4ce5d271c4416bfa144b9a94b89b9
Autor:
Zhiying Yin, Tingcui Wen, Canya Fu, Junji Li, Quanjun Fang, Xiaoying Gong, Jialing You, Shuangqing Wang, Canjie Zheng
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionLimited data were available on the effectivenessfour years after Homo or Hetero prime-boost with 10 μg Hansenulapolymorpha recombinant hepatitis B vaccine (HepB-HP) and 20 μgChinese hamster ovary cell HepB (HepB-CHO).MethodsA crosssecti
Externí odkaz:
https://doaj.org/article/fd8a5145130a4b0a8a1f61b7c01b1bbc