Zobrazeno 1 - 10
of 14 779
pro vyhledávání: '"primary sclerosing cholangitis"'
Autor:
Yingduo Yu, Qigu Yao, Deying Chen, Zhehua Zhang, Qiaoling Pan, Jiong Yu, Hongcui Cao, Liang Li, Lanjuan Li
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Background The metabolic patterns of human placental-derived mesenchymal stem cell (hP-MSC) treatment for primary sclerosing cholangitis (PSC) remain unclear, and therapeutic effects significantly vary due to individual differences. Therefor
Externí odkaz:
https://doaj.org/article/824f265bc9e44a7bbd40f1382604d590
Autor:
Roberta Angelico, Leandro Siragusa, Francesca Blasi, Vittoria Bellato, Michela Mineccia, Elisabetta Lolli, Giovanni Monteleone, Giuseppe S. Sica
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Introduction Patients with ulcerative colitis (UC) receiving liver transplantation (LT) due to primary sclerosing cholangitis (PSC) have higher risk of developing colorectal cancers (CRC). Aim of this systematic review was to define the pati
Externí odkaz:
https://doaj.org/article/f5290a82a29c437eb1d44fc89b7c4fda
Autor:
E. S. Pak, T. M. Petrova, R. V. Korobka, A. A. Ushakov, O. B. Kucherenko, V. Yu. Katsiyaev, O. V. Bukhtin
Publikováno v:
Медицинский вестник Юга России, Vol 15, Iss 3, Pp 97-105 (2024)
Primary sclerosing cholangitis (PSC) is a disease characterized by inflammation, fibrosis and obliteration of both intra- and extrahepatic bile ducts, accompanied by cholestasis, with further outcome in biliary cirrhosis of the liver, cholangiocarcin
Externí odkaz:
https://doaj.org/article/9070a933903841cdb5d6b2a329b27179
Publikováno v:
Open Medicine, Vol 19, Iss 1, Pp 2547-59 (2024)
No intervention definitively extends transplant-free survival in primary sclerosing cholangitis (PSC). Statins, inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR), may enhance PSC prognosis, but their efficacy is debated.
Externí odkaz:
https://doaj.org/article/bc06fd3e41234b4789ad5dc19ef1b1c4
Autor:
Ziwen Pan, Weijie Zhang
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-8 (2024)
Abstract Background Observational studies have found a link between two autoimmune diseases, namely, primary sclerosing cholangitis (PSC) and systemic lupus erythematosus (SLE). However, the relationship remains unclear. Methods Bidirectional Mendeli
Externí odkaz:
https://doaj.org/article/2fc9845b12b94c8fb9fa524f4801db44
Autor:
Muriel Huss, Tanja Elger, Johanna Loibl, Arne Kandulski, Benedicta Binder, Petra Stoeckert, Patricia Mester, Martina Müller, Christa Buechler, Hauke Christian Tews
Publikováno v:
Gastroenterology Insights, Vol 15, Iss 2, Pp 486-497 (2024)
Predicting responses and monitoring the severity of inflammatory bowel disease (IBD) is challenging due to a lack of specific biomarkers. This study identifies urinary hydroxyproline, a marker of collagen turnover elevated in experimental colitis, as
Externí odkaz:
https://doaj.org/article/674fceb030ff4accb2d4bb21a5762d3c
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-13 (2024)
Abstract Primary Sclerosing Cholangitis (PSC) is a progressive cholestatic liver disease with no licensed therapies. Previous Genome Wide Association Studies (GWAS) have identified genes that correlate significantly with PSC, and these were identifie
Externí odkaz:
https://doaj.org/article/c1bcbcd837f34175b375f4daaba3d662
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background The intricate etiology of autoimmune liver disease (AILD) involves genetic, environmental, and other factors that yet to be completely elucidated. This study comprehensively assessed the causal association between genetically pred
Externí odkaz:
https://doaj.org/article/7e959a0ea32543bc8ab85159f6be3ac2
Autor:
Tymoteusz Ślósarz, Rafał Kaczorowski, Tomasz Forenc, Aleksandra Pelczarska, Paulina Maria Krupa, Maciej Witkowski, Patryk Mejza, Anna Kaczorowska
Publikováno v:
Quality in Sport, Vol 24 (2024)
Introduction: Primary sclerosing cholangitis (PSC) is a complex liver disorder marked by multifocal bile duct strictures and dilatations, leading to cholestasis and liver fibrosis. Although the exact cause is unknown, autoimmune mechanisms are strong
Externí odkaz:
https://doaj.org/article/c70129c89c2545f1978ff8cf125c0279
Autor:
Lavinia Patricia Mocan, Cristiana Grapa, Rareș Crăciun, Ioana Ecaterina Pralea, Alina Uifălean, Andreea Maria Soporan, Ximena Maria Mureșan, Maria Iacobescu, Nadim Al Hajjar, Carmen Mihaela Mihu, Zeno Spârchez, Tudor Mocan, Cristina Adela Iuga
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Recent advancements in proteomics have shown promise in identifying biomarkers for various cancers. Our study is the first to compare the serum proteomes of intrahepatic cholangiocarcinoma (iCCA) with cirrhosis (CIR), primary sclerosing cholangitis (
Externí odkaz:
https://doaj.org/article/e0ca6d12d14c47a38992746f534de446