Zobrazeno 1 - 10
of 595
pro vyhledávání: '"premanifest"'
Autor:
S. A. Lobkov
Publikováno v:
Acta Biomedica Scientifica, Vol 9, Iss 4, Pp 146-152 (2024)
Background. The issues of early diagnostics and prevention of schizophrenia, despite more than a century of their study, remain relevant. In recent decades, there has been an increase in interest in the study of depersonalization-derealization sympto
Externí odkaz:
https://doaj.org/article/84ea29f834874f7a988517ee7126810e
Autor:
Marina Herrero‐Lorenzo, Jesús Pérez‐Pérez, Georgia Escaramís, Saül Martínez‐Horta, Rocío Pérez‐González, Elisa Rivas‐Asensio, Jaime Kulisevsky, Ana Gámez‐Valero, Eulàlia Martí
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 10, Pp n/a-n/a (2024)
Abstract Despite the advances in the understanding of Huntington's disease (HD), there is a need for molecular biomarkers to categorize mutation carriers during the preclinical stage of the disease preceding functional decline. Small RNAs (sRNAs) are
Externí odkaz:
https://doaj.org/article/65dc43036945447ca22a644c77da2673
Publikováno v:
Neurobiology of Disease, Vol 199, Iss , Pp 106574- (2024)
Proton magnetic resonance spectroscopy (1H-MRS) allows measuring specific brain metabolic alterations in Huntington's disease (HD), and these metabolite profiles may serve as non-invasive biomarkers associated with disease progression. Despite this p
Externí odkaz:
https://doaj.org/article/919289fdefb84f179c190c0c41f6cdb2
Autor:
Sophie C. Andrews, Lydia Kämpf, Dylan Curtin, Mark Hinder, Nicole Wenderoth, Julie C. Stout, James P. Coxon
Publikováno v:
Frontiers in Psychology, Vol 14 (2023)
IntroductionCardiorespiratory exercise has emerged as a promising candidate to modify disease progression in Huntington’s disease (HD). In animal models, exercise has been found to alter biomarkers of neuroplasticity and delay evidence of disease,
Externí odkaz:
https://doaj.org/article/75e69fc47fc046d9be4cce78f52d7f9e
Akademický článek
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Akademický článek
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Autor:
Paul Zeun, Peter McColgan, Thijs Dhollander, Sarah Gregory, Eileanoir B. Johnson, Marina Papoutsi, Akshay Nair, Rachael I. Scahill, Geraint Rees, Sarah J. Tabrizi
Publikováno v:
NeuroImage: Clinical, Vol 33, Iss , Pp 102927- (2022)
Objectives: To investigate the timeframe prior to symptom onset when cortico-basal ganglia white matter (white matter) loss begins in premanifest Huntington’s disease (preHD), and which striatal and thalamic sub-region white matter tracts are most
Externí odkaz:
https://doaj.org/article/fd0c448432f7454cb40720aa895efbbd
Autor:
Marianna Delussi, Vittorio Sciruicchio, Paolo Taurisano, Francesca Morgante, Elena Salvatore, Isabella Pia Ferrara, Livio Clemente, Chiara Sorbera, Marina de Tommaso
Publikováno v:
Brain Sciences, Vol 12, Iss 5, p 676 (2022)
Pain is a minor problem compared with other Huntington Disease (HD) symptoms. Nevertheless, in HD it is poorly recognized and underestimated. So far, no study evaluated the presence of chronic pain in HD. The aim of this pilot study was to evaluate t
Externí odkaz:
https://doaj.org/article/682eb37478d742a087f10f0a8f832e95
Autor:
Chiara Casella, Elena Kleban, Anne E. Rosser, Elizabeth Coulthard, Hugh Rickards, Fabrizio Fasano, Claudia Metzler-Baddeley, Derek K. Jones
Publikováno v:
NeuroImage: Clinical, Vol 30, Iss , Pp 102658- (2021)
White matter (WM) alterations have been identified as a relevant pathological feature of Huntington’s disease (HD). Increasing evidence suggests that WM changes in this disorder are due to alterations in myelin‐associated biological processes. Mu
Externí odkaz:
https://doaj.org/article/d652a201ca654acd8e553655c2b3b878
Akademický článek
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