Zobrazeno 1 - 10
of 346
pro vyhledávání: '"prefusion"'
Autor:
Akiko Mizukami, Victor Preckler, Frederik Verelst, Taizo Matsuki, Yufan Ho, Daisuke Kurai, Daniel Molnar
Publikováno v:
Expert Review of Vaccines, Vol 23, Iss 1, Pp 986-996 (2024)
Objectives Older adults (OA) are at risk of morbidity and mortality from respiratory syncytial virus (RSV), a major cause of seasonal acute respiratory illness. The first RSV vaccine for OA (RSVPreF3 OA) was recently launched in Japan. With the alrea
Externí odkaz:
https://doaj.org/article/21fe23ab10d14f46b920820743b90801
Autor:
Daisuke Kurai, Akiko Mizukami, Victor Preckler, Frederik Verelst, Daniel Molnar, Taizo Matsuki, Yufan Ho, Ataru Igarashi
Publikováno v:
Expert Review of Vaccines, Vol 23, Iss 1, Pp 303-311 (2024)
ABSTRACTBackground Respiratory syncytial virus (RSV), a common respiratory pathogen, can lead to severe symptoms, especially in older adults (OA). A recently developed RSV prefusion F protein (RSVPreF3 OA) vaccine confers high protection against RSV
Externí odkaz:
https://doaj.org/article/5257110ff0d74e0b89f9b9977b98216e
Autor:
Yi Pang, Haishan Lu, Demin Cao, Xiaoying Zhu, Qinqin Long, Fengqin Tian, Xidai Long, Yulei Li
Publikováno v:
BMC Public Health, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Objective A notable research gap exists in the systematic review and meta-analysis concerning the efficacy, immunogenicity, and safety of the respiratory syncytial virus (RSV) prefusion F vaccine. Methods We conducted a comprehensive search
Externí odkaz:
https://doaj.org/article/25cbf0d7678a49328ce36f01da6bd97d
Autor:
Jie Liu, Jie Sun, Xue Ding, Wenhao Liu, Yipeng Wang, Zihan Wang, Hanyu Peng, Yong Zhang, Weiheng Su, Chunlai Jiang
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
Rabies is a lethal zoonotic disease that threatens human health. As the only viral surface protein, the rabies virus (RABV) glycoprotein (G) induces main neutralizing antibody (Nab) responses; however, Nab titre is closely correlated with the conform
Externí odkaz:
https://doaj.org/article/65037c0fa4f64e178d0ed14000594e3c
Autor:
Rahul Ahuja, Preeti Vishwakarma, Sneha Raj, Varun Kumar, Ritika Khatri, Bharat Lohiya, Shikha Saxena, Gurleen Kaur, Gagandeep Singh, Shailendra Asthana, Shubbir Ahmed, Sweety Samal
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)
ABSTRACTMiddle East respiratory syndrome coronavirus (MERS-CoV) is a lethal beta-coronavirus that emerged in 2012. The virus is part of the WHO blueprint priority list with a concerning fatality rate of 35%. Scientific efforts are ongoing for the dev
Externí odkaz:
https://doaj.org/article/4e44e7d9cd2b4a2bae31dfb3939ef7df
Autor:
Karen J. Gonzalez, Kevin C. Yim, Jorge C. G. Blanco, Marina S. Boukhvalova, Eva-Maria Strauch
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Numerous enveloped viruses, such as coronaviruses, influenza, and respiratory syncytial virus (RSV), utilize class I fusion proteins for cell entry. During this process, the proteins transition from a prefusion to a postfusion state, undergoing subst
Externí odkaz:
https://doaj.org/article/06d092ee163546c58ed0ec67d45823c7
Autor:
Murdo Ferguson, Alexander Murray, Lew Pliamm, Lars Rombo, Johan Sanmartin Berglund, Marie-Pierre David, Nathalie De Schrevel, Franck Maschino, Shady Kotb, Aurélie Olivier, Veronica Hulstrøm
Publikováno v:
Vaccine: X, Vol 18, Iss , Pp 100494- (2024)
Background: Previous phase 3 studies showed that the AS01E-adjuvanted respiratory syncytial virus (RSV) prefusion F protein-based vaccine for older adults (RSVPreF3 OA) is well tolerated and efficacious in preventing RSV-associated lower respiratory
Externí odkaz:
https://doaj.org/article/b9ce1a2d0402470d812844986a1b8347
Autor:
Miguel Á. Muñoz-Alía, Rebecca A. Nace, Baskar Balakrishnan, Lianwen Zhang, Nandakumar Packiriswamy, Gagandeep Singh, Prajakta Warang, Ignacio Mena, Riya Narjari, Rianna Vandergaast, Kah-Whye Peng, Adolfo García-Sastre, Michael Schotsaert, Stephen J. Russell
Publikováno v:
mBio, Vol 15, Iss 2 (2024)
ABSTRACT Serum titers of SARS-CoV-2-neutralizing antibodies (nAbs) correlate well with protection from symptomatic COVID-19 but decay rapidly in the months following vaccination or infection. In contrast, measles-protective nAb titers are lifelong af
Externí odkaz:
https://doaj.org/article/cd8acd208724481bb4522d65973e788c
Autor:
Megolhubino Terhüja, Manjunath Siddappa, Pramila Lamichhane, Chetan D. Meshram, Timothy A. Snider, Jerry W. Ritchey, Antonius G. P. Oomens
Publikováno v:
Viruses, Vol 16, Iss 6, p 843 (2024)
Respiratory syncytial virus (RSV) is a major cause of severe respiratory tract disease worldwide, and a pediatric vaccine is not available. We generated a filamentous RSV-based virus-like particle (VLP) that presents the central conserved region of t
Externí odkaz:
https://doaj.org/article/b43bad425d5e43d9a8b2df644af6ede3
Autor:
Rana Abdelnabi, Patricia Pérez, David Astorgano, Guillermo Albericio, Winnie Kerstens, Hendrik Jan Thibaut, Lotte Coelmont, Birgit Weynand, Nuria Labiod, Rafael Delgado, Dolores Montenegro, Eugenia Puentes, Esteban Rodríguez, Johan Neyts, Kai Dallmeier, Mariano Esteban, Juan García-Arriaza
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The development of novel optimized vaccines against coronavirus disease 2019 (COVID-19) that are capable of controlling the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic and the appearance of different variants of concern (VoC
Externí odkaz:
https://doaj.org/article/68157076a75c4c40a3009c48ca5bfe3a