The effect of design and size of the fluid-bed equipment on the particle size-dependent trend of particle coating thickness and drug prolonged-release profile

Autor: Brezovar, Teja, Hudovornik, Grega, farmacevt, Perpar, Matjaž, strojnik, Luštrik, Matevž, doktor farmacije in dentalne medicine, Dreu, Rok

Publikováno v: AAPS PharmSciTech, vol. 24, no. 4, 93, 2023.
AAPS PharmSciTech, 16 str. : Graf. prikazi, tabele, Vol. 24, iss. 4, art. 93, 2023
COBISS-ID: 1247345

The focus of the current work is to study and demonstrate the impact of the design, the scale, and settings of fluid-bed coating equipment on the differences in pellet coating thickness, which in case of prolonged-release pellets dictates the drug re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::909af44d891fd789f1cf648decda8414
https://repozitorij.uni-lj.si/IzpisGradiva.php?id=145071

The Effect of Design and Size of the Fluid-Bed Equipment on the Particle Size-Dependent Trend of Particle Coating Thickness and Drug Prolonged-Release Profile.

Autor: Brezovar T; Faculty of Pharmacy, University of Ljubljana, Aškerčeva cesta 7, 1000, Ljubljana, Slovenia.; Krka, d.d., Novo mesto, Šmarješka cesta 6, 8501, Novo mesto, Slovenia., Hudovornik G; Krka, d.d., Novo mesto, Šmarješka cesta 6, 8501, Novo mesto, Slovenia., Perpar M; Faculty of Mechanical Engineering, University of Ljubljana, Aškerčeva cesta 6, 1000, Ljubljana, Slovenia., Luštrik M; Faculty of Pharmacy, University of Ljubljana, Aškerčeva cesta 7, 1000, Ljubljana, Slovenia.; Faculty of Medicine, University of Ljubljana, Vrazov trg 2, 1000, Ljubljana, Slovenia., Dreu R; Faculty of Pharmacy, University of Ljubljana, Aškerčeva cesta 7, 1000, Ljubljana, Slovenia. rok.dreu@ffa.uni-lj.si.

Publikováno v: AAPS PharmSciTech [AAPS PharmSciTech] 2023 Apr 01; Vol. 24 (4), pp. 93. Date of Electronic Publication: 2023 Apr 01.