Zobrazeno 1 - 10
of 199
pro vyhledávání: '"preclinical “in vivo” study"'
Autor:
Chiara Peres, Caterina Sellitto, Chiara Nardin, Sabrina Putti, Tiziana Orsini, Chiara Di Pietro, Daniela Marazziti, Adriana Vitiello, Arianna Calistri, Mara Rigamonti, Ferdinando Scavizzi, Marcello Raspa, Francesco Zonta, Guang Yang, Thomas W. White, Fabio Mammano
Publikováno v:
EBioMedicine, Vol 89, Iss , Pp 104453- (2023)
Summary: Background: Keratitis ichthyosis deafness (KID) syndrome is a rare disorder caused by hemichannel (HC) activating gain-of-function mutations in the GJB2 gene encoding connexin (Cx) 26, for which there is no cure, or current treatments based
Externí odkaz:
https://doaj.org/article/bd169d1992394aeab17af27a91b30026
Autor:
Mateusz Kachel, Piotr P. Buszman, Krzysztof P. Milewski, Magdalena Michalak, Wojciech Domaradzki, Maciej Pruski, Michał Sobota, Carlos Fernandez, Marta Konopko, Jerzy Nożyński, Paweł Kaźmierczak, Jakub Włodarczyk, Mateusz Stojko, Andrzej Bochenek, Paweł E. Buszman
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
ObjectivesThe aim of the study is to evaluate the functionality, durability, and temporal biocompatibility of a novel, balloon-expandable polymeric transcatheter heart valve (ATHV) system (InFlow, CardValve Consortium, Poland). Along with expanding T
Externí odkaz:
https://doaj.org/article/557453ff997543c489f7767176b64164
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-12 (2021)
Abstract Background Dental implants are considered the gold standard replacement for missing natural teeth. The successful clinical performance of dental implants is due to their ability to osseointegrate with the surrounding bone. Most dental implan
Externí odkaz:
https://doaj.org/article/7b3d7854d39d4298b5065686174f0a4d
Autor:
Michał Maurin, Monika Wyczółkowska, Agnieszka Sawicka, Arkadiusz Eugeniusz Sikora, Urszula Karczmarczyk, Barbara Janota, Marcin Radzik, Dominik Kłudkiewicz, Justyna Pijarowska-Kruszyna, Antoni Jaroń, Wioletta Wojdowska, Piotr Garnuszek
Publikováno v:
Molecules, Vol 27, Iss 21, p 7216 (2022)
Despite significant advances in nuclear medicine for diagnosing and treating prostate cancer (PCa), research into new ligands with increasingly better biological properties is still ongoing. Prostate-specific membrane antigen (PSMA) ligands show grea
Externí odkaz:
https://doaj.org/article/556af5e2d5bb4c0b94113b833c84ca41
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 0, Iss 1, Pp 168-176 (2019)
Active use of medical devices in contact with the blood stream has created the need to articulate the testing requirements of such products [1], various methods of modelling and assessment of potential complications. One of the most important aspects
Externí odkaz:
https://doaj.org/article/a2d4e0e5ce4e451590c42b45e99c6c3e
Autor:
Wenbo Liu, Xin Wang, Jinlei Su, Qingsong Jiang, Jing Wang, Yang Xu, Yudong Zheng, Zhihui Zhong, Hai Lin
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Dura substitutes are applied in duraplasty to repair lost or damaged dura. Collagen-based dura substitutes are mainstream products in both the US and Chinese markets. In this study, dura substitute devices with potential dura regeneration ability are
Externí odkaz:
https://doaj.org/article/2ea672e5d8a5485a8a96f1300c6695fb
Autor:
Sally Spendiff, Rachel Howarth, Grace McMacken, Tracey Davey, Kaitlyn Quinlan, Emily O'Connor, Clarke Slater, Stefan Hettwer, Armin Mäder, Andreas Roos, Rita Horvath, Hanns Lochmüller
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2020)
Introduction: Congenital myasthenic syndromes (CMS) are a diverse group of inherited neuromuscular disorders characterized by a failure of synaptic transmission at the neuromuscular junction (NMJ). CMS often present early with fatigable weakness and
Externí odkaz:
https://doaj.org/article/abdd85adee9246eda39df3320d66f035
Autor:
Alessia Peserico, Barbara Barboni, Valentina Russo, Delia Nardinocchi, Maura Turriani, Costanza Cimini, Nicola Bernabò, Ornella Parolini, Antonietta Rosa Silini, Ivana Antonucci, Liborio Stuppia, Paolo Berardinelli, Ilaria Falanga, Davide Perruzza, Luca Valbonetti, Annunziata Mauro
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 10; Pages: 8737
Amniotic membrane and amniotic fluid derived cells are regarded as a promising stem cell source for developing regenerative medicine techniques, although they have never been tested on male infertility diseases such as varicocele (VAR). The current s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7f8bf9a5f98e35d21a77b4cc3e306bb
https://hdl.handle.net/11575/130600
https://hdl.handle.net/11575/130600
Autor:
Muthu K. Shanmugam, Kwang Seok Ahn, Annie Hsu, Chern Chiuh Woo, Yi Yuan, Kwong Huat Benny Tan, Arunachalam Chinnathambi, Tahani Awad Alahmadi, Sulaiman Ali Alharbi, Angele Pei Fern Koh, Frank Arfuso, Ruby Yun-Ju Huang, Lina H. K. Lim, Gautam Sethi, Alan Prem Kumar
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Overexpression of chemokine receptor type 4 (CXCR4) has been found to be associated with increased cell proliferation, metastasis and also act as an indicator of poor prognosis in patients with breast cancer. Therefore, new agents that can abrogate C
Externí odkaz:
https://doaj.org/article/b215012bc4f64c1e873510fa61002aeb
Autor:
Robert Kraft, Jean Zheng Boyer, Eslie Dennis, Gail Lewis Phillips, Penny Towne, Elizabeth Vela, Karl Garsha, Brittany Admire, Hiro Nitta
Publikováno v:
Breast Cancer Research and Treatment
Background Cell spheroids and aggregates generated from three-dimensional (3D) cell culture methods are similar to in vivo tumors in terms of tissue morphology, biology, and gene expression, unlike cells grown in 2D cell cultures. Breast cancer heter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2076077709ca09221d656c1301bb0e95
http://europepmc.org/articles/PMC8233276
http://europepmc.org/articles/PMC8233276