Zobrazeno 1 - 10
of 2 591
pro vyhledávání: '"pre-replication complex"'
Publikováno v:
Biology, Vol 13, Iss 3, p 152 (2024)
In all eukaryotes, the initiation of DNA replication requires a stepwise assembly of factors onto the origins of DNA replication. This is pioneered by the Origin Recognition Complex, which recruits Cdc6. Together, they bring Cdt1, which shepherds MCM
Externí odkaz:
https://doaj.org/article/207e7829b2934a53a3e904c19a0055c3
Publikováno v:
Open Biology, Vol 10, Iss 7 (2020)
Replication origins in eukaryotes form a base for assembly of the pre-replication complex (pre-RC), thereby serving as an initiation site of DNA replication. Characteristics of replication origin vary among species. In fission yeast Schizosaccharomyc
Externí odkaz:
https://doaj.org/article/e6a9059c5ca244e48804a8364b817432
Publikováno v:
Philosophical Transactions: Biological Sciences, 2004 Jan . 359(1441), 7-16.
Externí odkaz:
https://www.jstor.org/stable/4142274
Autor:
Juliana Nogueira Brasil, Carinne N. Monteiro Costa, Luiz Mors Cabral, Paulo C. G. Ferreira, Adriana S. Hemerly
Publikováno v:
Genetics and Molecular Biology, Vol 40, Iss 1 suppl 1, Pp 276-291 (2017)
Abstract The multiplication of cells in all living organisms requires a tight regulation of DNA replication. Several mechanisms take place to ensure that the DNA is replicated faithfully and just once per cell cycle in order to originate through mito
Externí odkaz:
https://doaj.org/article/3f7211e4aa114ba68c057bf2882233e9
Publikováno v:
eLife, Vol 7 (2018)
DNA replication transforms cohesin rings dynamically associated with chromatin into the cohesive form to establish sister-chromatid cohesion. Here, we show that, in human cells, cohesin loading onto chromosomes during early S phase requires the repli
Externí odkaz:
https://doaj.org/article/7b6d4f3d203444c2b5086dd5e47d2cad
Akademický článek
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Autor:
Zuzana Nascakova, Vaclav Urban, Barbora Boleslavska, Edita Vlachova, Jana Dobrovolna, Anna Oravetzova, Pavel Janscak
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 3740, p 3740 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 7
International Journal of Molecular Sciences
Volume 22
Issue 7
R-loops are three-stranded structures generated by annealing of nascent transcripts to the template DNA strand, leaving the non-template DNA strand exposed as a single-stranded loop. Although R-loops play important roles in physiological processes su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8654ddb1bd18d5a08b9267e8c38c9c0c
https://www.mdpi.com/1422-0067/22/7/3740
https://www.mdpi.com/1422-0067/22/7/3740
Autor:
Michael Walser, Ossia M. Eichhoff, Rexha-Lambert C, Reinhard Dummer, Paul Widmer, Michael Daube, Evelyn Lattmann, Mitchell P. Levesque, Alex Hajnal, Ting Deng, Prasad
Cell invasion is an initiating event during tumor cell metastasis and an essential process during development. A screen of C. elegans orthologs of genes over-expressed in invasive human melanoma cells has identified several components of the conserve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d61744f9c4a22434bc4d2fc1bb5caf9b
https://doi.org/10.1101/2021.06.10.447853
https://doi.org/10.1101/2021.06.10.447853
Autor:
Susan L. Forsburg, Sarah A. Sabatinos
Publikováno v:
Biomolecules
Biomolecules, Vol 5, Iss 3, Pp 2123-2139 (2015)
Biomolecules, Vol 5, Iss 3, Pp 2123-2139 (2015)
Replication fork stalling generates a variety of responses, most of which cause an increase in single-stranded DNA. ssDNA is a primary signal of replication distress that activates cellular checkpoints. It is also a potential source of genome instabi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f333c06bf118fdfe6f6824310eeec302
https://doi.org/10.32920/14637963
https://doi.org/10.32920/14637963
Akademický článek
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