Zobrazeno 1 - 10
of 991
pro vyhledávání: '"pre-metastatic niche"'
Autor:
Mobina Bayat, Javid Sadri Nahand
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-29 (2024)
Abstract Organs of future metastasis are not passive receivers of circulating tumor cells, but are instead selectively and actively modified by the primary tumor before metastatic spread has even occurred. Tumors orchestrate a pre-metastatic program
Externí odkaz:
https://doaj.org/article/c328181b5f0344c2afef1fdfa0f2e887
Autor:
Shanyi Lin, Longqiang Shu, Yuhang Guo, Ji Yuan, Juntao Zhang, Yang Wang, Yunlong Yang, Ting Yuan
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Osteosarcoma (OS) derived small extracellular vesicles (OS-sEVs) have been shown to induce the formation of cancer-associated fibroblasts (CAFs), characterized by elevated pro-inflammatory factor expression and enhanced migratory and contrac
Externí odkaz:
https://doaj.org/article/933ab30648ef42a69c0087bb163eb04e
Autor:
Cong Li, Kexin Zhang, Zehua Cheng, Lihong Wang, Zehao Li, Chao Shen, Zhihang Li, Zeyu Wang, Lianrui Cao, Lijiang Chen
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 19, Iss 5, Pp 100949- (2024)
Tumor metastasis is responsible for 90 % of cancer-associated deaths, and its early detection may decrease the likelihood of mortality. Studies have demonstrated that metastasis results from the interaction between “seeds” (tumor cells) and “so
Externí odkaz:
https://doaj.org/article/651c518ab75c4b8e8db32716a45e6cbd
Autor:
Lucrezia Pisanu, Klodjana Mucaj, Valentina Conio, Francesco Bertuccio, Ilaria Giana, Lorenzo Arlando, Marianna Russo, Simone Montini, Chandra Bortolotto, Angelo Guido Corsico, Giulia Maria Stella
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
The lungs are most often a preferential target organ for malignant spreading and growth. It is well known that chronic parenchymal inflammation and prolonged injuries represents an independent risk factor for cancer onset. Growing evidence supports t
Externí odkaz:
https://doaj.org/article/dc4b45ef3af94018a749e0eae594cd2e
Autor:
YaNan Zhang, XiaoYan Wang, Yue Mou, YingZheng Wang, WeiDong Liu, WeiKe Feng, Rong Chen, MeiZhi Zhang, Jing Sun
Publikováno v:
Heliyon, Vol 10, Iss 19, Pp e38431- (2024)
Metastasis is the main cause of death in cancer patients, the lung is one of the most common metastatic organs of malignant solid tumors. Before tumor cells metastasize to the lungs, they interact with immunosuppressive cells, alveolar epithelial cel
Externí odkaz:
https://doaj.org/article/d5cd2cca0f9d4cf2823c1ab76efd31f1
Autor:
Susana García-Silva, Héctor Peinado
Publikováno v:
European Journal of Cell Biology, Vol 103, Iss 3, Pp 151447- (2024)
In several solid tumors such as breast cancer, prostate cancer, colorectal cancer or melanoma, tumor draining lymph nodes are the earliest tissues where colonization by tumor cells is detected. Lymph nodes act as sentinels of metastatic dissemination
Externí odkaz:
https://doaj.org/article/2a13ae6ac51649e6a627ec0eca442873
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The successful pulmonary metastasis of malignant cancer cells depends on the survival of circulating tumor cells in a distant and hostile microenvironment. The formation of a pre-metastatic niche (PMN) creates a supportive environment for subsequent
Externí odkaz:
https://doaj.org/article/50a3ed91c45d456d8f859ffe2314a110
Autor:
Zhuang Chen, Qiming Wang, Jinbo Liu, Wenkang Wang, Weitang Yuan, Yang Liu, Zhenqiang Sun, Chengzeng Wang
Publikováno v:
Genes and Diseases, Vol 11, Iss 1, Pp 176-188 (2024)
A pre-metastatic niche (PMN) is a protective microenvironment that facilitates the colonization of disseminating tumor cells in future metastatic organs. Extracellular vesicles (EVs) play a role in intercellular communication by delivering cargoes, s
Externí odkaz:
https://doaj.org/article/1dcb8dbf8d8e45e3bcbe972e11dd3824
Autor:
Yi-Chih Chang, Hao-Ping Liu, Hsiao-Li Chuang, Jiunn-Wang Liao, Pei-Ling Kao, Hsun-Lung Chan, Ter-Hsin Chen, Yu-Chih Wang
Publikováno v:
Laboratory Animal Research, Vol 39, Iss 1, Pp 1-15 (2023)
Abstract Background Feline mammary carcinoma (FMC) is one of the most prevalent malignancies of female cats. FMC is highly metastatic and thus leads to poor disease outcomes. Among all metastases, liver metastasis occurs in about 25% of FMC patients.
Externí odkaz:
https://doaj.org/article/bddfc0cba0d946c884c2448336f42502
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-18 (2023)
Abstract Current research has demonstrated that extracellular vesicles (EVs) and circulating tumor cells (CTCs) are very closely related in the process of distant tumor metastasis. Primary tumors are shed and released into the bloodstream to form CTC
Externí odkaz:
https://doaj.org/article/06bf1df73e084bac92e6441203fb04a5