Zobrazeno 1 - 10
of 335
pro vyhledávání: '"pre‐erythrocytic"'
Autor:
Julio A. Ventocilla, L. Lorena Tapia, Reynaldo Ponce, Adriano Franco, Mindy Leelawong, Joao C. Aguiar, G. Christian Baldeviano, Brandon K. Wilder
Publikováno v:
Malaria Journal, Vol 23, Iss 1, Pp 1-15 (2024)
Abstract Background Plasmodium vivax represents the most geographically widespread human malaria parasite affecting civilian and military populations in endemic areas. Targeting the pre-erythrocytic (PE) stage of the parasite life cycle is especially
Externí odkaz:
https://doaj.org/article/43b92ad773b94c2c9fb473acbfd4495b
Autor:
Debashree Goswami, Hardik Patel, William Betz, Janna Armstrong, Nelly Camargo, Asha Patil, Sumana Chakravarty, Sean C Murphy, B Kim Lee Sim, Ashley M Vaughan, Stephen L Hoffman, Stefan HI Kappe
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 4, Pp 723-754 (2024)
Abstract Vaccination with infectious Plasmodium falciparum (Pf) sporozoites (SPZ) administered with antimalarial drugs (PfSPZ-CVac), confers superior sterilizing protection against infection when compared to vaccination with replication-deficient, ra
Externí odkaz:
https://doaj.org/article/2fcc440695074e599b621cd9032c9199
Autor:
Gabriela Maíra Pereira de Assis, Denise Anete Madureira de Alvarenga, Luisa Braga e Souza, Juan Camilo Sánchez-Arcila, Eduardo Fernandes e Silva, Anielle de Pina-Costa, Gustavo Henrique Pereira Gonçalves, Júlio César de Junior Souza, Ana Julia Dutra Nunes, Alcides Pissinatti, Silvia Bahadian Moreira, Leticia de Menezes Torres, Helena Lott Costa, Herlandes da Penha Tinoco, Valéria do Socorro Pereira, Irene da Silva Soares, Taís Nóbrega de Sousa, Francis Babila Ntumngia, John H. Adams, Flora Satiko Kano, Zelinda Maria Braga Hirano, Lilian Rose Pratt-Riccio, Cláudio Tadeu Daniel-Ribeiro, Joseli Oliveira Ferreira, Luzia Helena Carvalho, Cristiana Ferreira Alves de Brito
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
IntroductionZoonotic transmission is a challenge for the control and elimination of malaria. It has been recorded in the Atlantic Forest, outside the Amazon which is the endemic region in Brazil. However, only very few studies have assessed the antib
Externí odkaz:
https://doaj.org/article/57ca36ac0b244c6b9d6cee528534385b
Akademický článek
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Publikováno v:
Risk Management and Healthcare Policy, Vol Volume 14, Pp 1033-1039 (2021)
Navneet Arora, Lokhesh C Anbalagan, Ashok K Pannu Postgraduate Institute of Medical Education and Research, Chandigarh, IndiaCorrespondence: Ashok K PannuDepartment of Internal Medicine, Postgraduate Institute of Medical Education and Research, 4th F
Externí odkaz:
https://doaj.org/article/951bd78dec5d4cafb1e1480581b3d49b
Autor:
Katja Müller, Matthew P Gibbins, Mark Roberts, Arturo Reyes‐Sandoval, Adrian V S Hill, Simon J Draper, Kai Matuschewski, Olivier Silvie, Julius Clemence R Hafalla
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 4, Pp 1-15 (2021)
Abstract Immunogenicity is considered one important criterion for progression of candidate vaccines to further clinical evaluation. We tested this assumption in an infection and vaccination model for malaria pre‐erythrocytic stages. We engineered P
Externí odkaz:
https://doaj.org/article/ea7d1952472d4ad6bd50a7cba4c4f6a0
Autor:
Arif Jamal Siddiqui, Jyoti Bhardwaj, Manish Goyal, Kirtika Prakash, Mohd Adnan, Mousa M. Alreshidi, Mitesh Patel, Awakash Soni, Whitni Redman
Publikováno v:
Journal of Advanced Research, Vol 24, Iss , Pp 29-41 (2020)
Though the immunity to malaria has been associated with cellular immune responses, the exact function of the phenotypic cell population is still unclear. This study investigated the host immune responses elicited during the pre-erythrocytic stage, po
Externí odkaz:
https://doaj.org/article/e970a393932e4bafb225752c61ef4e6a
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Host cell remodeling is critical for successful Plasmodium replication inside erythrocytes and achieved by targeted export of parasite-encoded proteins. In contrast, during liver infection the malarial parasite appears to avoid protein export, perhap
Externí odkaz:
https://doaj.org/article/7bef57bfd68b4648a86339c82b32823c
Autor:
Carlota Dobaño, Itziar Ubillos, Chenjerai Jairoce, Ben Gyan, Marta Vidal, Alfons Jiménez, Rebeca Santano, David Dosoo, Augusto J. Nhabomba, Aintzane Ayestaran, Ruth Aguilar, Nana Aba Williams, Núria Díez-Padrisa, David Lanar, Virander Chauhan, Chetan Chitnis, Sheetij Dutta, Deepak Gaur, Evelina Angov, Kwaku Poku Asante, Seth Owusu-Agyei, Clarissa Valim, Benoit Gamain, Ross L. Coppel, David Cavanagh, James G. Beeson, Joseph J. Campo, Gemma Moncunill
Publikováno v:
BMC Medicine, Vol 17, Iss 1, Pp 1-19 (2019)
Abstract Background Vaccination and naturally acquired immunity against microbial pathogens may have complex interactions that influence disease outcomes. To date, only vaccine-specific immune responses have routinely been investigated in malaria vac
Externí odkaz:
https://doaj.org/article/b537671e318343a6a6e9016896cf4fdc
Publikováno v:
Expert Review of Vaccines, Vol 18, Iss 2, Pp 133-151 (2019)
Introduction: The challenge to eradicate malaria is an enormous task that will not be achieved by current control measures, thus an efficacious and long-lasting malaria vaccine is required. The licensing of RTS, S/AS01 is a step forward in providing
Externí odkaz:
https://doaj.org/article/fdb77a1d3b6c4f86a603c147422556bf