Zobrazeno 1 - 10
of 1 822
pro vyhledávání: '"ppi network"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The transcription factors NANOG and POU5F1 (OCT4) play crucial roles in maintaining pluripotency in embryonic stem (ES) cells. While their functions have been well-studied, the specific interactions between NANOG and POU5F1 and their combine
Externí odkaz:
https://doaj.org/article/41cc54ffb34c439ea08aff2b1f1f9605
Publikováno v:
Thrombosis Journal, Vol 22, Iss 1, Pp 1-10 (2024)
Abstract Background Increased hemoglobin concentrations may increase the risk of varicose veins. However, the underlying relationship between them was not yet understood. Methods Mendelian randomization (MR) analysis was performed to investigate caus
Externí odkaz:
https://doaj.org/article/3d1a10157c6b4e119ab898d8aa51bce9
Autor:
Giulia Pozzati, Jinrui Zhou, Hananel Hazan, Giannoula Lakka Klement, Hava T. Siegelmann, Jack A. Tuszynski, Edward A. Rietman
Publikováno v:
Onco, Vol 4, Iss 3, Pp 163-191 (2024)
Whole-genome sequencing has revealed that TP53, NOTCH1, ATM, SF3B1, BIRC3, ABL, NXF1, BCR, and ZAP70 are often mutated in CLL, but not consistently across all CLL patients. This paper employs a statistical thermodynamics approach in combination with
Externí odkaz:
https://doaj.org/article/cbb7a77e2b574368b5b57277c1b9f346
Publikováno v:
Biochemistry and Biophysics Reports, Vol 40, Iss , Pp 101860- (2024)
Background: Uterine corpus endometrial carcinoma (UCEC), derived from the endometrium, is the most common type of endometrial malignasis. This gynecological malignancy is very common all over the world, especially in developed countries and shows a p
Externí odkaz:
https://doaj.org/article/93c68d6f54c7477e97d46db8b823e2e5
Autor:
Xiaoning Zhang, Jie Shi, Yilong Lu, Rui Ji, Zhiyu Guan, Fujun Peng, Chunzhen Zhao, Wei Gao, Feng Gao
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Cryptosporidiosis is a worldwide zoonotic disease. Oxymatrine, an alkaloid extracted and isolated from the plant bitter ginseng, has been reported to have therapeutic effects on cryptosporidiosis. However, the underlying mechanism of its act
Externí odkaz:
https://doaj.org/article/243f01f7e8dc48ae88dcb998f6896ff2
Publikováno v:
PeerJ, Vol 12, p e18068 (2024)
Background As a powerful tool, bioinformatics analysis is playing an increasingly important role in many fields. Osteogenic differentiation is a complex biological process involving the fine regulation of numerous genes and signaling pathways. Method
Externí odkaz:
https://doaj.org/article/0b38165ffa6e459488cbfaba9dce2463
Autor:
Chuanxi Tian, Jinyue Zhao, Qian Wang, Keke Luo, Shuang Zhao, Li Wan, Jiarui Li, Kaile Ma, Yanyan Zhou, Min Li
Publikováno v:
Arabian Journal of Chemistry, Vol 17, Iss 9, Pp 105910- (2024)
Background: Huashi Baidu granule (HSBD), an approved herbal formula for treating COVID-19, demonstrates safety and efficacy. Despite its market approval, the detailed methodology and identification of its active components remain unexplored, leaving
Externí odkaz:
https://doaj.org/article/9b95f4c49dd04420bb5976aef8127fd0
Autor:
Ashwini Kumar Ray, Anjali Priya, Md. Zubbair Malik, Thangavel Alphonse Thanaraj, Alok Kumar Singh, Payal Mago, Chirashree Ghosh, Shalimar, Ravi Tandon, Rupesh Chaturvedi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Cardiovascular disease (CVD) is a collective term for disorders of the heart and blood vessels. The molecular events and biochemical pathways associated with CVD are difficult to study in clinical settings on patients and in vitro conditions
Externí odkaz:
https://doaj.org/article/ae5cf1cc292b4c5a9beba8ec45ed8251
Publikováno v:
BMC Gastroenterology, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Ulcerative colitis (UC) is a chronic inflammatory disease that targets the colon and has seen an increasing prevalence worldwide. In our pursuit of new diagnostic and therapeutic approaches for UC, we undertook a sequencing of colons from UC
Externí odkaz:
https://doaj.org/article/5bf5135bc3234076984923ca7195d1cc
Publikováno v:
Human Genomics, Vol 18, Iss 1, Pp 1-34 (2024)
Abstract Background It is valuable to analyze the genome-wide association studies (GWAS) data for a complex disease phenotype in the context of the protein–protein interaction (PPI) network, as the related pathophysiology results from the function
Externí odkaz:
https://doaj.org/article/f65624d528d84560b68d3a750e0e86ed