Zobrazeno 1 - 10
of 535
pro vyhledávání: '"ppara"'
Publikováno v:
Regenerative Therapy, Vol 26, Iss , Pp 33-41 (2024)
Background: The morbidity and mortality of sepsis are increasing year by year. Statistically, 40–50% of patients with sepsis have concomitant myocardial injury, and its mortality rate is higher than that of patients with sepsis only. Therefore, it
Externí odkaz:
https://doaj.org/article/e161e882e85e4ac2848a88ba91c8a87c
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-13 (2024)
Abstract Background Acute myocardial infarction (AMI) is a serious cardiovascular disease that adversely affects human health. Circular RNAs (circRNAs) are involved in the pathological and physiological processes of AMI, but the biological mechanism
Externí odkaz:
https://doaj.org/article/f567e6da827144ec814b8e38cb7c7a2d
Publikováno v:
Journal of Functional Foods, Vol 122, Iss , Pp 106459- (2024)
This study explored the active ingredients and mechanism of Pleurotus placentodes extract (PP-a) in alleviating acute liver injury. According to un-targeted metabolomics analysis, 102 compounds were identified in PP-a, 32 were regarded as active comp
Externí odkaz:
https://doaj.org/article/37287b2865fe46bfb53e44d30a377f63
Autor:
Celal Bulgay, Ladislav Cepicka, Metin Dalip, Selin Yıldırım, Halil İ. Ceylan, Özlem Ö. Yılmaz, Korkut Ulucan, Georgian Badicu, Mesut Cerit
Publikováno v:
BMC Sports Science, Medicine and Rehabilitation, Vol 15, Iss 1, Pp 1-15 (2023)
Abstract Background Current research on athletic performance focuses on genetic variants that contribute significantly to individuals’ performance. ACTN3 rs1815739 and PPARA-α rs4253778 gene polymorphisms are variants frequently associated with at
Externí odkaz:
https://doaj.org/article/33e1f564ad634dfe8dfd897e65fa7e14
Publikováno v:
Cells, Vol 13, Iss 10, p 831 (2024)
Peroxisome proliferator-activated receptor alpha (PPARA) is a ligand-activated transcription factor that is a key mediator of lipid metabolism and metabolic stress in the liver. Accumulating evidence shows that PPARA regulates the expression of vario
Externí odkaz:
https://doaj.org/article/c7cc8ab711fe4d428f231ca3353244b2
Publikováno v:
Folia Neuropathologica, Vol 61, Iss 2, Pp 138-143 (2023)
Peroxisome proliferator-activated receptors α (PPARα) are members of the nuclear receptors family and a very potent transcription factor engaged in the regulation of lipid and energy metabolism. Recent data suggest that PPARα could play an importa
Externí odkaz:
https://doaj.org/article/8b11331915f14cb893b5bee50af5ac55
Publikováno v:
Open Biology, Vol 13, Iss 11 (2023)
Externí odkaz:
https://doaj.org/article/dff6a4a655a84a8083a73ad466f1aa10
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 2, p 68 (2024)
Chronic obstructive pulmonary disease (COPD) is a complex respiratory disorder influenced by various factors and involving multiple genes. Respiratory dysfunction in COPD patients leads to hypoxia, resulting in limited oxygen uptake. Peroxisome proli
Externí odkaz:
https://doaj.org/article/ceda943e2c4c404ca8418cccdc3b1640
Autor:
Jin Xu, Wen-jie Chen, Zhan Wang, Ming-yuan Xin, Shen-han Gao, Wen-jing Liu, Kai-kun Wang, Jing-wei Ma, Xin-zong Yan, Yan-ming Ren
Publikováno v:
Proteome Science, Vol 20, Iss 1, Pp 1-13 (2022)
Abstract Background Hypoxia is a risk factor for non-alcoholic fatty liver diseases, leading to permanent imbalance of liver lipid homeostasis and steatohepatitis. However, a detailed understanding of the metabolic genes and pathways involved remains
Externí odkaz:
https://doaj.org/article/f55f46c1c60741aaae69ad28dbbd0055
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundSepsis is a heterogeneous disease, therefore the single-gene-based biomarker is not sufficient to fully understand the disease. Higher-level biomarkers need to be explored to identify important pathways related to sepsis and evaluate their
Externí odkaz:
https://doaj.org/article/b64b0709e3c34947aae124dea5e4c33e