Zobrazeno 1 - 10
of 412
pro vyhledávání: '"pparβ"'
Publikováno v:
Drug Design, Development and Therapy, Vol Volume 18, Pp 4799-4824 (2024)
Chaoying Jin,1,2,* Ruolin Zhao,3,4,* Weihang Hu,5 Xiaolong Wu,4 Li Zhou,6 Letian Shan,4,6 Huiling Wu1,2 1Department of Plastic and Aesthetic Center, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, 3
Externí odkaz:
https://doaj.org/article/13133f3c7a22494ba9370494d80ce3eb
Autor:
Meijian Zhang, Emma Barroso, Lucía Peña, Patricia Rada, Ángela M. Valverde, Walter Wahli, Xavier Palomer, Manuel Vázquez-Carrera
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 179, Iss , Pp 117303- (2024)
The role of peroxisome proliferator-activated receptor (PPAR)β/δ in hepatic fibrosis remains a subject of debate. Here, we examined the effects of a PPARβ/δ agonist on the pathogenesis of liver fibrosis and the activation of hepatic stellate cell
Externí odkaz:
https://doaj.org/article/bd3f461a588d498c847ef3d9ba500e5e
Autor:
Yan Zhang, Xue-Ying Zhang, Shan-Rui Shi, Chao-Nan Ma, Yun-Peng Lin, Wen-Gang Song, Shou-Dong Guo
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
Inflammation and dyslipidemia are critical inducing factors of atherosclerosis. Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors and control the expression of multiple genes that are involved in lipid met
Externí odkaz:
https://doaj.org/article/0e5db45833464d9f807b622381245aa0
Publikováno v:
International Journal of Nanomedicine, Vol Volume 18, Pp 5095-5117 (2023)
Yingjing Pan,1,* Tianci Lin,1,* Longquan Shao,2 Yulin Zhang,2 Qiao Han,3 Liyuan Sheng,4 Rui Guo,5 Ting Sun,1 Yanli Zhang2 1Foshan Stomatological Hospital, School of Medicine, Foshan University, Foshan, 528225, People’s Republic of China; 2S
Externí odkaz:
https://doaj.org/article/ecefb51192304a0a90f631d544d6552c
Autor:
Blanca Rubio, Cristina Pintado, Lorena Mazuecos, Marina Benito, Antonio Andrés, Nilda Gallardo
Publikováno v:
Biomolecules, Vol 14, Iss 8, p 1028 (2024)
Leptin, acting centrally or peripherally, has complex effects on cardiac remodeling and heart function. We previously reported that central leptin exerts an anti-hypertrophic effect in the heart via cardiac PPARβ/δ activation. Here, we assessed the
Externí odkaz:
https://doaj.org/article/6781c77f75004f7ca47459188b872cfc
Publikováno v:
Heliyon, Vol 10, Iss 4, Pp e26572- (2024)
Hypoxic exercise is an effective intervention for obesity, because it promotes weight loss by regulating fatty acid (FA) metabolism. The regulation of peroxisome proliferator-activated receptor β (PPARβ) by miR-122 may be involved in this process,
Externí odkaz:
https://doaj.org/article/dc3257c88934470b964704fced041eac
Autor:
Alexandre Barbaud, Isabelle Lascombe, Adeline Péchery, Sergen Arslan, François Kleinclauss, Sylvie Fauconnet
Publikováno v:
Cells, Vol 13, Iss 8, p 708 (2024)
Bladder cancer aggressiveness is correlated with abnormal N-cadherin transmembrane glycoprotein expression. This protein is cleaved by the metalloprotease ADAM10 and the γ-secretase complex releasing a pro-angiogenic N-terminal fragment (NTF) and a
Externí odkaz:
https://doaj.org/article/92c50a6603444135bf1a95076863f2e1
Autor:
Meijian Zhang, Emma Barroso, Maria Ruart, Lucía Peña, Mona Peyman, David Aguilar-Recarte, Marta Montori-Grau, Patricia Rada, Clara Cugat, Carla Montironi, Mohammad Zarei, Javier Jurado-Aguilar, Antoni Camins, Jesús Balsinde, Ángela M. Valverde, Walter Wahli, Xavier Palomer, Manuel Vázquez-Carrera
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 167, Iss , Pp 115623- (2023)
Elafibranor is a dual peroxisome proliferator-activated receptor (PPAR)α and β/δ agonist that has reached a phase III clinical trial for the treatment of metabolic dysfunction-associated steatotic liver disease (MASLD). Here, we examined the effec
Externí odkaz:
https://doaj.org/article/482a0be0b5064142a7d350a00b86da03
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Akademický článek
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