Zobrazeno 1 - 10
of 9 626
pro vyhledávání: '"posttranslational modification"'
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Ubiquitination and deubiquitination are important forms of posttranslational modification that govern protein homeostasis. Deubiquitinating enzymes (DUBs), a protein superfamily consisting of more than 100 members, deconjugate ubiquitin chai
Externí odkaz:
https://doaj.org/article/be832de6c2344d1585efd96155d54739
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-30 (2024)
Abstract The interaction between programmed cell death ligand 1 (PD-L1), which is expressed on the surface of tumor cells, and programmed cell death 1 (PD-1), which is expressed on T cells, impedes the effective activation of tumor antigen-specific T
Externí odkaz:
https://doaj.org/article/54da51af37014f4d8cfcefb955719543
Publikováno v:
Cell Division, Vol 19, Iss 1, Pp 1-28 (2024)
Abstract CIP/KIP and INK4 families of Cyclin-dependent kinase inhibitors (CKIs) are well-established cell cycle regulatory proteins whose canonical function is binding to Cyclin-CDK complexes and altering their function. Initial experiments showed th
Externí odkaz:
https://doaj.org/article/fc925f7e928d4793810e068ec2401fea
Autor:
Yi Qu, Nannan Gao, Shengwei Zhang, Limin Gao, Bing He, Chao Wang, Chunli Gong, Qiuyue Shi, Zhibin Li, Shiming Yang, Yufeng Xiao
Publikováno v:
MedComm, Vol 5, Iss 9, Pp n/a-n/a (2024)
Abstract N6‐methyladenosine (m6A) is the most abundant modification of RNA in eukaryotic cells. Previous studies have shown that m6A is pivotal in diverse diseases especially cancer. m6A corelates with the initiation, progression, resistance, invas
Externí odkaz:
https://doaj.org/article/49a6a16569fd4f6289a8fa5b6ca75736
Publikováno v:
mBio, Vol 15, Iss 9 (2024)
ABSTRACT Rhomboid proteases are universally conserved and facilitate the proteolysis of peptide bonds within or adjacent to cell membranes. While eukaryotic rhomboid proteases have been demonstrated to harbor unique cellular roles, prokaryotic member
Externí odkaz:
https://doaj.org/article/9367e23d2b25481eb369775c4f69f3fb
Publikováno v:
Genes and Diseases, Vol 11, Iss 5, Pp 101060- (2024)
Protein lysine crotonylation (Kcr) is one conserved form of posttranslational modifications of proteins, which plays an important role in a series of cellular physiological and pathological processes. Lysine ε-amino groups are the primary sites of s
Externí odkaz:
https://doaj.org/article/462c88e9ef814b76a2be787331164376
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e35303- (2024)
Glioma is one of the prevalent malignancies, and identifying therapeutic targets for glioma is highly important. Findings of current study revealed that inositol-trisphosphate 3-kinase A (ITPKA) was found abnormally over expressed and thereby exhibit
Externí odkaz:
https://doaj.org/article/effb2100e98840e08ec260663605121a