Zobrazeno 1 - 10
of 220
pro vyhledávání: '"postsynaptic density protein 95"'
Akademický článek
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Autor:
Marta Barrera-Conde, Emma Veza-Estévez, Maria Gomis-Gonzalez, Jordi Garcia-Quintana, Amira Trabsa, Laura Martínez-Sadurní, Mitona Pujades, Víctor Perez, Rafael de la Torre, Daniel Bergé, Patricia Robledo
Publikováno v:
Neurobiology of Disease, Vol 176, Iss , Pp 105942- (2023)
Cyclin-dependent kinase 5 (CDK5) is a serine/threonine kinase that has emerged as a key regulator of neurotransmission in complex cognitive processes. Its expression is altered in treated schizophrenia patients, and cannabinoids modulate CDK5 levels
Externí odkaz:
https://doaj.org/article/1311498fab70475cb0f5fa3e93837bf2
Publikováno v:
Di-san junyi daxue xuebao, Vol 43, Iss 7, Pp 629-634 (2021)
Objective To explore the effect and possible machanism of recombinant adeno-associated virus (rAAV) vector containing brain-derived neurotrophic factor propeptide (AAV-pBDNF) on learning and memory in APPswePS1dE9 transgenic mice (Alzheimer's disease
Externí odkaz:
https://doaj.org/article/95dc80b815a44932a90f36dea460c38e
Autor:
Yu-Fei Luo, Xiao-Xia Ye, Ying-Zhao Fang, Meng-Die Li, Zhi-Xuan Xia, Jian-Min Liu, Xiao-Shan Lin, Zhen Huang, Xiao-Qian Zhu, Jun-Jie Huang, Dong-Lin Tan, Yu-Fei Zhang, Hai-Ping Liu, Jun Zhou, Zu-Cheng Shen
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: The mechanistic target of rapamycin complex 1 (mTORC1) signaling has served as a promising target for therapeutic intervention of major depressive disorder (MDD), but the mTORC1 signaling underlying MDD has not been well elucidated. In th
Externí odkaz:
https://doaj.org/article/3aadb14777de4859af08bac8ae503cc2
Akademický článek
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Publikováno v:
Neural Regeneration Research, Vol 14, Iss 3, Pp 462-469 (2019)
Cerebral ischemia activates an endogenous repair program that induces plastic changes in neurons. In this study, we investigated the effects of environmental enrichment on spatial learning and memory as well as on synaptic remodeling in a mouse model
Externí odkaz:
https://doaj.org/article/deea5c860bf04d0f86878d5cb3a0d45d
Autor:
Xu-Sheng Yan, Zhan-Jun Yang, Jian-Xin Jia, Wei Song, Xin Fang, Zhi-Ping Cai, Dong-Sheng Huo, He Wang
Publikováno v:
Neural Regeneration Research, Vol 14, Iss 4, Pp 649-657 (2019)
Cognitive dysfunction in Alzheimer’s disease is strongly associated with a reduction in synaptic plasticity, which may be induced by oxidative stress. Testosterone is beneficial in learning and memory, although the underlying protective mechanism o
Externí odkaz:
https://doaj.org/article/92ad65725fbe4a83b97159d7b9d03903
Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
Autor:
Jary Y. Delgado
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2020)
Phosphorylation-dependent peptidyl-prolyl cis-trans isomerization plays key roles in cell cycle progression, the pathogenesis of cancer, and age-related neurodegeneration. Most of our knowledge about the role of phosphorylation-dependent peptidyl-pro
Externí odkaz:
https://doaj.org/article/4be78e048b7f437087d2a8cd202da34e
Autor:
Tamara Janković, Petra Dolenec, Jelena Rajič Bumber, Nika Gržeta, Jasna Kriz, Gordana Župan, Kristina Pilipović
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 22, p 12211 (2021)
Traumatic brain injury (TBI) is a disabling disorder and a major cause of death and disability in the world. Both single and repetitive traumas affect the brain acutely but can also lead to chronic neurodegenerative changes. Clinical studies have sho
Externí odkaz:
https://doaj.org/article/dfebb96dfcc04465a1797aa429e0c190