Zobrazeno 1 - 10
of 1 507
pro vyhledávání: '"postmortem studies"'
Autor:
Gift Ahimbisibwe, Marjorie Nakibuule, Marvin Martin Ssejoba, David Oyamo, Rose Mulwana, Josephine Nabulime, Febronius Babirye, Musana Abdusalaamu Kizito, Hervé Monka Lekuya, Akello Suzan Adakun, Daisy Nalumansi, Stella Muryasingura, Robert Lukande, Andrew Kyazze, Joseph Baruch Baluku, Irene Andia Biraro, Stephen Cose
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionIf we are to break new ground in difficult-to-treat or difficult-to-vaccinate diseases (such as HIV, malaria, or tuberculosis), we must have a better understanding of the immune system at the site of infection in humans. For tuberculosis
Externí odkaz:
https://doaj.org/article/73950710c66b438a9701d1dc3fe8ebd4
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Neural transplantation is a potential therapeutic method for Parkinson’s disease (PD). Fetal dopaminergic (DA) neurons have been important transplantation cell sources in the history of replacement therapy for PD. Several decades of preclinical ani
Externí odkaz:
https://doaj.org/article/a660a87f78d84555a78d19f1217c76fb
Akademický článek
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Publikováno v:
Schizophrenia Research. 249:63-73
Numerous genetic and postmortem studies link N-methyl-d-aspartate receptor (NMDAR) dysfunction with schizophrenia, forming the basis of the popular glutamate hypothesis. Neuronal NMDAR abnormalities are consistently reported from both basic and clini
Autor:
Hirjak, D., Ams, M., Gass, P., Kubera, K. M., Sambataro, F., Foucher, J. R., Northoff, G., Wolf, R. C.
Publikováno v:
Schizophrenia Research.
Autor:
Yoshihiro Noda, Guillermo Horga, Fernando Caravaggio, Clifford M. Cassidy, Ariel Graff-Guerrero, Edgardo Torres-Carmona, Sho Moriguchi, Shiori Honda, Vincenzo De Luca, Sakiko Tsugawa, Philip Gerretsen, Shinichiro Nakajima, Yusuke Iwata, Fumihiko Ueno, Jose M. Rubio
Publikováno v:
Neurosci Biobehav Rev
Although schizophrenia is associated with increased presynaptic dopamine function in the striatum, it remains unclear if neuromelanin levels, which are thought to serve as a biomarker for midbrain dopamine neuron function, are increased in patients w
Autor:
Divya Dwivedi, Vaishali Badhautia, Khushboo Punjabi, Deepika Shukla, Pravat K. Mandal, Ritwick Mishra, Manjari Tripathi
Publikováno v:
Journal of Alzheimer's Disease. 84:1139-1152
Background: Oxidative stress plays a major role in Alzheimer’s disease (AD) pathogenesis, and thus, antioxidant glutathione (GSH) has been actively investigated in mitigating the oxidative load. Significant hippocampal GSH depletion has been correl
Publikováno v:
Otology & Neurotology. 42:1585-1593
Objective After 160 years the true underlying cause of Meniere's disease remains enigmatic. The aim of our study is to discuss the possible implication of an obstruction of the ductus reuniens as a cause in Meniere's disease. Methodology We first con
Autor:
Kanwal Zahra, Javaid Munir, Fakhar uz Zaman, Zia ul Haq, Zulfiqar Ali Buzdar, Muhammad Anwar Sibtain Fazli, Maryam Shahid
Publikováno v:
Pakistan Journal of Medical and Health Sciences. 15:2319-2322
Background: Performing identity is a prime task in medicolegal and postmortem examinations. Age is the first parameter that has to be determined followed by sex. There are several techniques through which sex can be determined. As well there are diff
Publikováno v:
Molecular Psychiatry. 27:758-770
The spreading of misfolded alpha-synuclein (α-syn) protein has been observed in animal models of Parkinson's disease (PD) and other α-synucleinopathies that mimic human PD pathologies. In animal models, the spreading of α-syn has been associated w