Zobrazeno 1 - 10
of 1 954
pro vyhledávání: '"post-transcriptional modification"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
cAMP response element-binding protein (CREB) is a ubiquitously expressed nuclear transcription factor, which can be constitutively activated regardless of external stimuli or be inducibly activated by external factors such as stressors, hormones, neu
Externí odkaz:
https://doaj.org/article/627bc4f3a6da413394193c61754f64bd
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Nuclear factor erythroid 2 (NF-E2)-related factor 3 (NFE2L3), a member of the CNC-bZIP subfamily and widely found in a variety of tissues, is an endoplasmic reticulum (ER) membrane-anchored transcription factor that can be released from the ER and mo
Externí odkaz:
https://doaj.org/article/ac4beb48f5b7404099791d7bd10f1d51
Publikováno v:
Acta Biochimica et Biophysica Sinica, Vol 55, Pp 988-1000 (2023)
Esophageal cancer is one of the major life-threatening diseases in the world. RNA methylation is the most common post-transcriptional modification and a wide-ranging regulatory system controlling gene expression. Numerous studies have revealed that d
Externí odkaz:
https://doaj.org/article/74c78a0c250244c5a7a544e1a59beec3
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The COVID-19 pandemic caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) virus has had a significant impact on global social and economic stability. To combat this, researchers have turned to omics approaches, particularly epi
Externí odkaz:
https://doaj.org/article/cfe8533a62db44a7baa430c2e6b34c6e
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Retinoic acid-inducible gene-I (RIG-I) like receptor (RLR) pathway is one of the most significant pathways supervising aberrant RNA in cells. In predominant conditions, the RLR pathway initiates anti-infection function via activating inflammatory eff
Externí odkaz:
https://doaj.org/article/f7cf2d5d7b3246cc95f0ed25651091c4
Publikováno v:
Mycobiology, Vol 50, Iss 5, Pp 357-365 (2022)
AbstractSchizophyllum commune has emerged as the most promising model mushroom to study developmental stages (mycelium, primordium), which are two primary processes of fruit body development. Long non-coding RNA (lncRNA) has been proved to participat
Externí odkaz:
https://doaj.org/article/c5f37af22fd64bb7a790fb2a28f73112
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-14 (2022)
Abstract Background The cnidarian myxozoan parasite Tetracapsuloides bryosalmonae causes chronic proliferative kidney disease (PKD) in salmonids. This parasite is a serious threat to wild and cultured salmonids. T. bryosalmonae undergoes intra-lumina
Externí odkaz:
https://doaj.org/article/5ebac9798492482d98d09c5ea38115f8
Autor:
Akiko Soma, Atsushi Kubota, Daisuke Tomoe, Yoshiho Ikeuchi, Fujio Kawamura, Hijiri Arimoto, Yuh Shiwa, Yu Kanesaki, Hideaki Nanamiya, Hirofumi Yoshikawa, Tsutomu Suzuki, Yasuhiko Sekine
Publikováno v:
Genes, Vol 14, Iss 8, p 1515 (2023)
Post-transcriptional modifications of tRNA are crucial for their core function. The inosine (I; 6-deaminated adenosine) at the first position in the anticodon of tRNAArg(ICG) modulates the decoding capability and is generally considered essential for
Externí odkaz:
https://doaj.org/article/cebad8d1d6064fada33597e1dfdbfac9
Autor:
Gangqiang Guo, Kan Pan, Su Fang, Lele Ye, Xinya Tong, Zhibin Wang, Xiangyang Xue, Huidi Zhang
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 26, Iss , Pp 575-593 (2021)
5-methylcytosine (m5C) post-transcriptional modifications affect the maturation, stability, and translation of the mRNA molecule. These modifications play an important role in many physiological and pathological processes, including stress response,
Externí odkaz:
https://doaj.org/article/2bc64b8307ac426cbfcf1f5625b184c9
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
N6-methyladenosine (m6A) is one of the most important RNA modifications, which is involved in many biological activities. Computational methods have been developed to detect m6A sites due to their high efficiency and low costs. As one of the most wid
Externí odkaz:
https://doaj.org/article/b24c03b9f3aa42ada165c6c621f4e4b0