Zobrazeno 1 - 10
of 797
pro vyhledávání: '"positive feedback loop"'
Autor:
Yan Zhuang, Yiding Ai, Peng Li, Xin Yue, Yue Li, Luling Shan, Tongtong Wang, Peng Zhao, Xun Jin
Publikováno v:
Cancer Biology & Medicine, Vol 21, Iss 10, Pp 916-933 (2024)
Objective: Colorectal cancer (CRC) is a prevalent malignant tumor with a high fatality rate. CircPDIA4 has been shown to have a vital role in cancer development by acting as a facilitator. Nevertheless, the impact of the circPDIA4/miR-9-5p/SP1 axis o
Externí odkaz:
https://doaj.org/article/2c55908f0256420c88335b1525e259a2
Autor:
Hui Qiu, Zhiying Shao, Xin Wen, Debao Qu, Zhengyang Liu, Ziqin Chen, Xinyan Zhang, Xin Ding, Longzhen Zhang
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Radioresistance and immune escape are crucial reasons for unsatisfactory therapeutic effects of glioblastoma (GBM). Although triggering receptor expressed on myeloid cells-2 (TREM2) involved in forming immunosuppressive microenvir
Externí odkaz:
https://doaj.org/article/ffc87da269e343c58f8c0d16862670bf
Autor:
Feng Xiao, Hong Zhu, Yaping Xiong, Yun Guo, Zhe Zhang, Jie Zeng, Yao Xiao, Bin Liao, Xuesong Shang, Siyi Zhao, Guowen Hu, Kai Huang, Hua Guo
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-19 (2024)
Abstract Background Recent studies have highlighted the significant role of the NF-κB signaling pathway in the initiation and progression of cancer. Furthermore, long noncoding RNAs (lncRNAs) have been identified as pivotal regulators in sustaining
Externí odkaz:
https://doaj.org/article/c1ff45ab488c4edbb8d397555e56b8fc
Publikováno v:
Transportation Research Interdisciplinary Perspectives, Vol 28, Iss , Pp 101277- (2024)
Truck platooning pertains to virtually coupling trucks to cut aerodynamic drag. Despite its many benefits, the dynamics of the trucking industry in adopting this technology is not well understood. In this paper, we investigate the dynamics and partic
Externí odkaz:
https://doaj.org/article/0a784eded25d4c3389334b0ecb08f2fe
Autor:
Minghai Ma, Xing Li, Minxuan Jing, Pu Zhang, Mengzhao Zhang, Lu Wang, Xiao Liang, Yunzhong Jiang, Jianpeng Li, Jiale He, Xinyang Wang, Min Lin, Lei Wang, Jinhai Fan
Publikováno v:
Advanced Science, Vol 11, Iss 42, Pp n/a-n/a (2024)
Abstract Peptide‐based drugs hold great potential for cancer treatment, and their effectiveness is driven by mechanisms on how peptides target cancer cells and escape from potential lysosomal entrapment post‐endocytosis. Yet, the mechanisms remai
Externí odkaz:
https://doaj.org/article/80b78c2de9a74d64abfba314b1804d43
Publikováno v:
Advanced Electronic Materials, Vol 10, Iss 9, Pp n/a-n/a (2024)
Abstract This study presents a binarized neural network (BNN) comprising quasi‐nonvolatile memory (QNVM) devices that operate in a positive feedback loop mechanism and exhibit an extremely low subthreshold swing (≤ 5 mV dec−1) and a high on/off
Externí odkaz:
https://doaj.org/article/4294adea874242fd8d2f8e6e6ae1767d
Autor:
Kai‐Ming Zhang, De‐Chang Zhao, Ze‐Yu Li, Yan Wang, Jian‐Nan Liu, Tian Du, Ling Zhou, Yu‐Hong Chen, Qi‐Chao Yu, Qing‐Shan Chen, Rui‐Zhao Cai, Zi‐Xuan Zhao, Jia‐Lu Shan, Bing‐Xin Hu, Hai‐Liang Zhang, Gong‐Kan Feng, Xiao‐Feng Zhu, Jun Tang, Rong Deng
Publikováno v:
Advanced Science, Vol 11, Iss 35, Pp n/a-n/a (2024)
Abstract Endocrine‐resistant ER+HER2– breast cancer (BC) is particularly aggressive and leads to poor clinical outcomes. Effective therapeutic strategies against endocrine‐resistant BC remain elusive. Here, analysis of the RNA‐sequencing data
Externí odkaz:
https://doaj.org/article/0bb97eb8b1b84525bea91c117811fad7
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract In this study, a binarized neural network (BNN) of silicon diode arrays achieved vector–matrix multiplication (VMM) between the binarized weights and inputs in these arrays. The diodes that operate in a positive-feedback loop in their p+-n
Externí odkaz:
https://doaj.org/article/83756f46aba04eaaa245de1f3c194208