Zobrazeno 1 - 10
of 81
pro vyhledávání: '"pore blocker"'
Autor:
Tang, Dongfang a, b, Xu, Jiahui c, Bao, Wenhu a, Xu, Fanping a, Qi, Jieqiong a, Tan, Zheni a, Li, Chuanli a, Luo, Xiaofang a, You, Xia b, Rong, Mingqiang b, ∗∗, Liu, Zhonghua b, ∗∗∗, Tang, Cheng b, ⁎
Publikováno v:
In European Journal of Pharmacology 5 February 2025 988
Autor:
Nikita A. Orlov, Elena V. Kryukova, Anastasia V. Efremenko, Sergey A. Yakimov, Victoria A. Toporova, Mikhail P. Kirpichnikov, Oksana V. Nekrasova, Alexey V. Feofanov
Publikováno v:
Membranes, Vol 13, Iss 7, p 645 (2023)
The voltage-gated potassium channel Kv1.1, which is abundant in the CNS and peripheral nervous system, controls neuronal excitability and neuromuscular transmission and mediates a number of physiological functions in non-excitable cells. The developm
Externí odkaz:
https://doaj.org/article/cfb44605bfc640008fec3610b2320174
Historical Perspective of the Characterization of Conotoxins Targeting Voltage-Gated Sodium Channels
Autor:
James R. Groome
Publikováno v:
Marine Drugs, Vol 21, Iss 4, p 209 (2023)
Marine toxins have potent actions on diverse sodium ion channels regulated by transmembrane voltage (voltage-gated ion channels) or by neurotransmitters (nicotinic acetylcholine receptor channels). Studies of these toxins have focused on varied aspec
Externí odkaz:
https://doaj.org/article/0a54c95e1aae410097d3e9202bda9284
Autor:
Nikita A. Orlov, Anastasia A. Ignatova, Elena V. Kryukova, Sergey A. Yakimov, Mikhail P. Kirpichnikov, Oksana V. Nekrasova, Alexey V. Feofanov
Publikováno v:
Toxins, Vol 14, Iss 12, p 858 (2022)
The voltage-gated potassium Kv1.3 channel is an essential component of vital cellular processes which is also involved in the pathogenesis of some autoimmune, neuroinflammatory and oncological diseases. Pore blockers of the Kv1.3 channel are consider
Externí odkaz:
https://doaj.org/article/2905dd7e5aa7467a9870eac99fe0995e
Autor:
Kristina R. Denisova, Nikita A. Orlov, Sergey A. Yakimov, Mikhail P. Kirpichnikov, Alexey V. Feofanov, Oksana V. Nekrasova
Publikováno v:
Bioengineering, Vol 9, Iss 7, p 295 (2022)
Fluorescently labeled peptide blockers of ion channels are useful probes in studying the localization and functioning of the channels and in the performance of a search for new channel ligands with bioengineering screening systems. Here, we report on
Externí odkaz:
https://doaj.org/article/fe12d2e85cd942369de5dcec0d938c27
Akademický článek
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Autor:
Feofanov, Nikita A. Orlov, Elena V. Kryukova, Anastasia V. Efremenko, Sergey A. Yakimov, Victoria A. Toporova, Mikhail P. Kirpichnikov, Oksana V. Nekrasova, Alexey V.
Publikováno v:
Membranes; Volume 13; Issue 7; Pages: 645
The voltage-gated potassium channel Kv1.1, which is abundant in the CNS and peripheral nervous system, controls neuronal excitability and neuromuscular transmission and mediates a number of physiological functions in non-excitable cells. The developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::f7af9e91514f45bcbc9c3a357a91ec51
Autor:
Katharina Ernst, Marc Landenberger, Julian Nieland, Katharina Nørgaard, Manfred Frick, Giorgio Fois, Roland Benz, Holger Barth
Publikováno v:
Toxins, Vol 13, Iss 6, p 390 (2021)
The clinically highly relevant Clostridioides (C.) difficile releases several AB-type toxins that cause diseases such as diarrhea and pseudomembranous colitis. In addition to the main virulence factors Rho/Ras-glycosylating toxins TcdA and TcdB, hype
Externí odkaz:
https://doaj.org/article/1354e412c0384bd7bc854bf912f952d8
Autor:
Kirsten L. McMahon, Hue N.T. Tran, Jennifer R. Deuis, Richard J. Lewis, Irina Vetter, Christina I. Schroeder
Publikováno v:
Biomedicines, Vol 8, Iss 10, p 391 (2020)
Voltage-gated sodium (NaV) channel subtypes, including NaV1.7, are promising targets for the treatment of neurological diseases, such as chronic pain. Cone snail-derived µ-conotoxins are small, potent NaV channel inhibitors which represent potential
Externí odkaz:
https://doaj.org/article/87d2528db7ac4b578c4599f9372afea0
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.