Zobrazeno 1 - 10
of 162
pro vyhledávání: '"polyfunctional T cells"'
Autor:
Stephan J. Holtkamp, Florian R. Lagoda, Adam Lister, Pradeep Harish, Ulrike Kleymann, Theresa Pesch, Chai Fen Soon, Munir Pirmohamed, Dean Naisbitt, Mark Trautwein
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Polyfunctional T cells programmed to perform activities such as degranulation of lytic enzymes and simultaneous production of multiple cytokines are associated with more effective control of viral infections. Immune responses to recombinant adeno-ass
Externí odkaz:
https://doaj.org/article/c5020e034cff45e69f917a6e10973642
Autor:
Gounwa Awad, Toralf Roch, Ulrik Stervbo, Sviatlana Kaliszczyk, Anna Stittrich, Jan Hörstrup, Ocan Cinkilic, Heiner Appel, Larysa Natrus, Ludmila Gayova, Felix Seibert, Frederic Bauer, Timm Westhoff, Mikalai Nienen, Nina Babel
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 21, Iss , Pp 288-298 (2021)
While virus-specific antibodies are broadly recognized as correlates of protection, virus-specific T cells are important for direct clearance of infected cells. Failure to generate hepatitis B virus (HBV)-specific antibodies is well-known in patients
Externí odkaz:
https://doaj.org/article/777b12b352f44ab2b993d5db26ca8318
Autor:
Dulharie T. Wijeratne, Samitha Fernando, Laksiri Gomes, Chandima Jeewandara, Geethal Jayarathna, Yashoda Perera, Samurdhi Wickramanayake, Ananda Wijewickrama, Graham S. Ogg, Gathsaurie N. Malavige
Publikováno v:
Immunity, Inflammation and Disease, Vol 7, Iss 4, Pp 276-285 (2019)
Abstract Introduction Although the role of dengue virus (DENV)‐specific T cells in the pathogenesis of acute dengue infection is emerging, the functionality of virus‐specific T cells associated with milder clinical disease has not been well studi
Externí odkaz:
https://doaj.org/article/0809ebf5295943e8b7bb78feb4d2710c
Akademický článek
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Autor:
Maria C. Ramello, Nicolás G. Núñez, Jimena Tosello Boari, Sabrina N. Bossio, Fernando P. Canale, Carolina Abrate, Nicolas Ponce, Andrés Del Castillo, Marta Ledesma, Sophie Viel, Wilfrid Richer, Christine Sedlik, Carolina Tiraboschi, Marcos Muñoz, Daniel Compagno, Adriana Gruppi, Eva V. Acosta Rodríguez, Eliane Piaggio, Carolina L. Montes
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Senescent T cells have been described during aging, chronic infections, and cancer; however, a comprehensive study of the phenotype, function, and transcriptional program of this T cell population in breast cancer (BC) patients is missing. Compared t
Externí odkaz:
https://doaj.org/article/33ccf8dcf8ac4fcdacbeebf8c5960cbb
Autor:
Daniel Watterson, Danushka K Wijesundara, Naphak Modhiran, Francesca L Mordant, Zheyi Li, Michael S Avumegah, Christopher LD McMillan, Julia Lackenby, Kate Guilfoyle, Geert vanAmerongen, Koert Stittelaar, Stacey TM Cheung, Summa Bibby, Mallory Daleris, Kym Hoger, Marianne Gillard, Eve Radunz, Martina L Jones, Karen Hughes, Ben Hughes, Justin Goh, David Edwards, Judith Scoble, Lesley Pearce, Lukasz Kowalczyk, Tram Phan, Mylinh La, Louis Lu, Tam Pham, Qi Zhou, David A Brockman, Sherry J Morgan, Cora Lau, Mai H Tran, Peter Tapley, Fernando Villalón‐Letelier, James Barnes, Andrew Young, Noushin Jaberolansar, Connor AP Scott, Ariel Isaacs, Alberto A Amarilla, Alexander A Khromykh, Judith MA van denBrand, Patrick C Reading, Charani Ranasinghe, Kanta Subbarao, Trent P Munro, Paul R Young, Keith J Chappell
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 4, Pp n/a-n/a (2021)
Abstract Objectives Efforts to develop and deploy effective vaccines against severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) continue at pace. Here, we describe rational antigen design through to manufacturability and vaccine efficac
Externí odkaz:
https://doaj.org/article/75b08e009f4c4222be30bd2650f67488
Autor:
Veerupaxagouda Patil, Sankar Renu, Ninoshkaly Feliciano-Ruiz, Yi Han, Anikethana Ramesh, Jennifer Schrock, Santosh Dhakal, Harm HogenEsch, Gourapura J. Renukaradhya
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
We designed the killed swine influenza A virus (SwIAV) H1N2 antigen (KAg) with polyriboinosinic:polyribocytidylic acid [(Poly(I:C)] adsorbed corn-derived Nano-11 particle based nanovaccine called Nano-11-KAg+Poly(I:C), and evaluated its immune correl
Externí odkaz:
https://doaj.org/article/3ea7d1d319854a52a540b64a1edb0a58
Autor:
Didier Payen, Maxime Cravat, Hadil Maadadi, Carole Didelot, Lydia Prosic, Claire Dupuis, Marie-Reine Losser, Marcelo De Carvalho Bittencourt
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Little is known about the time-dependent immune responses in severe COVID-19. Data of 15 consecutive patients were sequentially recorded from intensive care unit admission. Lymphocyte subsets and total monocyte and subsets counts were monitored as we
Externí odkaz:
https://doaj.org/article/1561382305e241879159a36c02aeec3a
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Previous studies suggest that the presence of antigen-specific polyfunctional T cells is correlated with improved pathogen clearance, disease control, and clinical outcomes; however, the molecular mechanisms responsible for the generation, function,
Externí odkaz:
https://doaj.org/article/15fea7815b4642f280d6750e6a88ccfe
Autor:
Loveline N. Ngu, Nadesh N. Nji, Georgia Ambada, Apeh A. Ngoh, Ghislain D. Njambe Priso, Jules C. Tchadji, Abel Lissom, Suzanne H. Magagoum, Carol N. Sake, Thibau F. Tchouangueu, George O. Chukwuma, Arinze S. Okoli, Bertrand Sagnia, Rebecca Chukwuanukwu, Denis M. Tebit, Charles O. Esimone, Alain B. Waffo, Chae G. Park, Klaus Überla, Godwin W. Nchinda
Publikováno v:
Immunity, Inflammation and Disease, Vol 6, Iss 1, Pp 163-175 (2018)
Abstract Introduction Recombinant Newcastle Disease virus (rNDV) vectored vaccines are safe mucosal applicable vaccines with intrinsic immune‐modulatory properties for the induction of efficient immunity. Like all viral vectored vaccines repeated i
Externí odkaz:
https://doaj.org/article/c6f6d59a92f34bf996af2b7457b55f93