Genotoxicity and subchronic toxicological study of a novel ginsenoside derivative 25-OCH3-PPD in beagle dogs

Autor: Wei Li, Yu-Qing Zhao, Yaoxian Xuan, Yanfei Xin, Xiangrong Zhang, Meng Ding

Publikováno v: Journal of Ginseng Research, Vol 43, Iss 4, Pp 562-571 (2019)
Journal of Ginseng Research

Background: Ginsenosides have been widely used clinically for many years and were regarded as very safe. However, a few researches on the toxicities of these kinds of agents showed that some ginsenosides may have side-effect on the rats or dogs. So i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::401dcdab4202f4f949af09e9f57b0068
https://doi.org/10.1016/j.jgr.2018.05.005

Genotoxicity and subchronic toxicological study of a novel ginsenoside derivative 25-OCH 3 -PPD in beagle dogs.

Autor: Li W; Department of Functional Food and Wine, Shenyang pharmaceutical University, Shenyang, China.; Key Laboratory of Structure-Based Drug Design & Discovery of Ministry of Education, Shenyang, China., Zhang X; Department of Functional Food and Wine, Shenyang pharmaceutical University, Shenyang, China.; Key Laboratory of Structure-Based Drug Design & Discovery of Ministry of Education, Shenyang, China., Ding M; Department of Functional Food and Wine, Shenyang pharmaceutical University, Shenyang, China., Xin Y; Center of Safety Evaluation, Zhejiang Academy of Medical Sciences, Hangzhou, China., Xuan Y; Center of Safety Evaluation, Zhejiang Academy of Medical Sciences, Hangzhou, China., Zhao Y; Department of Functional Food and Wine, Shenyang pharmaceutical University, Shenyang, China.; Key Laboratory of Structure-Based Drug Design & Discovery of Ministry of Education, Shenyang, China.

Publikováno v: Journal of ginseng research [J Ginseng Res] 2019 Oct; Vol. 43 (4), pp. 562-571. Date of Electronic Publication: 2018 May 31.