Zobrazeno 1 - 10
of 602
pro vyhledávání: '"poly(ADP-ribose) polymerase 1"'
Autor:
You Zuo, Jiaqian He, Zheng Zhou, Jingjing Sun, Can Ouyang, Hui Huang, Yajuan Wang, Hairong Liu, Simon H. Reed
Publikováno v:
Non-coding RNA Research, Vol 9, Iss 3, Pp 649-658 (2024)
In recent years, various long non-coding RNAs (lncRNAs) involved in DNA damage response (DDR) have been identified and studied to deepen our understanding. However, there are rare reports on the association between lncRNAs and base excision repair (B
Externí odkaz:
https://doaj.org/article/f6e460879406499fb1d08933b6cbb872
Publikováno v:
Exploration of Medicine, Vol 4, Iss 5, Pp 822-838 (2023)
Progeroid syndromes are characterized by clinical signs of premature ageing, which may contain several diseases such as Werner syndrome, Bloom syndrome, Rothmund-Thomson syndrome, Hutchinson-Gilford progeria syndrome, and Cockayne syndrome. These dis
Externí odkaz:
https://doaj.org/article/3ca2e96a22d74bce821f1147f5ff2d09
Publikováno v:
陆军军医大学学报, Vol 45, Iss 16, Pp 1682-1692 (2023)
Objective To investigate the role and molecular mechanism of poly (ADP-ribose) polymerase 1 (PARP1) in mitosis of HeLa cells. Methods Flow cytometry, immunofluorescent assay and live cell imaging were used to detect the effect of PARP1 on mitosis of
Externí odkaz:
https://doaj.org/article/e035423f691a4d9787549af2c36f03f3
Autor:
Natale Badalamenti, Antonella Maggio, Gianfranco Fontana, Maurizio Bruno, Marianna Lauricella, Antonella D’Anneo
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 3925 (2024)
The antitumor activity of different ent-kaurane diterpenes has been extensively studied. Several investigations have demonstrated the excellent antitumor activity of synthetic derivatives of the diterpene atractyligenin. In this research, a series of
Externí odkaz:
https://doaj.org/article/bc2d49c7232743058e072f08de8c64fe
Autor:
Svetlana N. Khodyreva, Ekaterina S. Ilina, Nadezhda S. Dyrkheeva, Alina S. Kochetkova, Alexandra A. Yamskikh, Ekaterina A. Maltseva, Anastasia A. Malakhova, Sergey P. Medvedev, Suren M. Zakian, Olga I. Lavrik
Publikováno v:
Cells, Vol 13, Iss 4, p 302 (2024)
Base excision repair (BER) is the predominant pathway for the removal of most forms of hydrolytic, oxidative, and alkylative DNA lesions. The precise functioning of BER is achieved via the regulation of each step by regulatory/accessory proteins, wit
Externí odkaz:
https://doaj.org/article/0983d4f52fdc49359c9bed4462992ed4
Akademický článek
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Akademický článek
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Autor:
Tatiana V. Andreeva, Natalya V. Maluchenko, Anastasiya V. Efremenko, Alexander V. Lyubitelev, Anna N. Korovina, Dmitry A. Afonin, Mikhail P. Kirpichnikov, Vasily M. Studitsky, Alexey V. Feofanov
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 14187 (2023)
The natural flavonoid epigallocatechin gallate has a wide range of biological activities, including being capable of binding to nucleic acids; however, the mechanisms of the interactions of epigallocatechin gallate with DNA organized in chromatin hav
Externí odkaz:
https://doaj.org/article/37749248e6874c0996f3ea4b70cdcf3d
Autor:
Hui Li, Zhenhua Wang, Yuanyuan Hou, Jianxin Xi, Zhenqiang He, Han Lu, Zhishan Du, Sheng Zhong, Qunying Yang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The current standard treatments of glioma include surgical resection, supplemented with radiotherapy and chemotherapy, but the prognosis is poor. PARP-1 (Poly ADP-ribose polymerase 1) is a hot spot for cancer-targeted therapy and was reported to be s
Externí odkaz:
https://doaj.org/article/6d3df755ae30418b8bf5968f182ac547
Akademický článek
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