Zobrazeno 1 - 10
of 54
pro vyhledávání: '"poly(ADP-ribose) glycohydrolase (Parg)"'
Autor:
Emad Matanes, Vanessa M. López-Ozuna, David Octeau, Tahira Baloch, Florentin Racovitan, Amandeep Kaur Dhillon, Roy Kessous, Oded Raban, Liron Kogan, Shannon Salvador, Susie Lau, Walter H. Gotlieb, Amber Yasmeen
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundPoly ADP-ribose glycohydrolase (PARG) is responsible for the catabolism of PARP-synthesized PAR to free ADP-ribose. Inhibition of PARG leads to DNA repair interruption and consequently induces cell death. This study aims to evaluate the eff
Externí odkaz:
https://doaj.org/article/0d9e891b94894a599e68b3cae7e6c7f2
Autor:
Pandey, Dheeraj
Adenosine diphosphate (ADP) ribosylation is a post-translational modification dependent on the transfer of ADPr units from nicotinamide adenine dinucleotide (NAD+) on to a plethora of biomolecules (i.e., proteins, DNA, RNA, etc.) in response to physi
Externí odkaz:
http://hdl.handle.net/10393/45637
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
Poly(ADP-ribose) polymerases (PARPs) are a family of enzymes that catalyze the addition of poly(ADP-ribose) (PAR) subunits onto themselves and other acceptor proteins. PARPs are known to function in a large range of cellular processes including DNA r
Externí odkaz:
https://doaj.org/article/04d95c5d2ace4596acecc99477fb1506
Autor:
C.A. Brosey, Davide Moiani, Leslie S. Warden, Shobanbabu Bommagani, John A. Tainer, Panagiotis Katsonis, Olivier Lichtarge, Todd M. Link, Zamal Ahmed, Darin E. Jones, Andy Arvai, Jerry H. Houl, Albino Bacolla, Lakshitha P.F. Balapiti-Modarage
Publikováno v:
Progress in Biophysics and Molecular Biology
Arrival of the novel SARS-CoV-2 has launched a worldwide effort to identify both pre-approved and novel therapeutics targeting the viral proteome, highlighting the urgent need for efficient drug discovery strategies. Even with effective vaccines, inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5969135f8e4ac8f12c9f9de86d773513
https://pubmed.ncbi.nlm.nih.gov/33636189
https://pubmed.ncbi.nlm.nih.gov/33636189
Autor:
Florentin Racovitan, David Octeau, Emad Matanes, Liron Kogan, Amber Yasmeen, Tahira Baloch, Susie Lau, Oded Raban, Walter H. Gotlieb, Roy Kessous, Amandeep Kaur Dhillon, Shannon Salvador, Vanessa M. López-Ozuna
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, Vol 11 (2021)
Frontiers in Oncology, Vol 11 (2021)
BackgroundPoly ADP-ribose glycohydrolase (PARG) is responsible for the catabolism of PARP-synthesized PAR to free ADP-ribose. Inhibition of PARG leads to DNA repair interruption and consequently induces cell death. This study aims to evaluate the eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2d291f26d8ce82c933c29da4890bcce
http://europepmc.org/articles/PMC8578901
http://europepmc.org/articles/PMC8578901
Autor:
Palmiro Poltronieri, Nataša Čerekovic
Publikováno v:
Challenges, Vol 9, Iss 1, p 3 (2018)
NAD+ has emerged as a crucial element in both bioenergetic and signaling pathways since it acts as a key regulator of cellular and organism homeostasis. NAD+ is a coenzyme in redox reactions, a donor of adenosine diphosphate-ribose (ADPr) moieties in
Externí odkaz:
https://doaj.org/article/42dbf2f2b90d4d56af16b974226cf181
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
Frontiers in Molecular Biosciences
Frontiers in Molecular Biosciences
Poly(ADP-ribose) polymerases (PARPs) are a family of enzymes that catalyze the addition of poly(ADP-ribose) (PAR) subunits onto themselves and other acceptor proteins. PARPs are known to function in a large range of cellular processes including DNA r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53faeb229e9ac32c8ecda601e699041f
https://www.frontiersin.org/article/10.3389/fmolb.2020.00191/full
https://www.frontiersin.org/article/10.3389/fmolb.2020.00191/full
ADP-Ribosylation as Post-Translational Modification of Proteins: Use of Inhibitors in Cancer Control
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 10829, p 10829 (2021)
International journal of molecular sciences (Online) 22 (2021): 829. doi:10.3390/ijms221910829
info:cnr-pdr/source/autori:Poltronieri P.; Miwa M.; Masutani M./titolo:ADP-ribosylation as post-translational modification of proteins: use of inhibitors in cancer control/doi:10.3390%2Fijms221910829/rivista:International journal of molecular sciences (Online)/anno:2021/pagina_da:829/pagina_a:/intervallo_pagine:829/volume:22
International Journal of Molecular Sciences
International journal of molecular sciences (Online) 22 (2021): 829. doi:10.3390/ijms221910829
info:cnr-pdr/source/autori:Poltronieri P.; Miwa M.; Masutani M./titolo:ADP-ribosylation as post-translational modification of proteins: use of inhibitors in cancer control/doi:10.3390%2Fijms221910829/rivista:International journal of molecular sciences (Online)/anno:2021/pagina_da:829/pagina_a:/intervallo_pagine:829/volume:22
International Journal of Molecular Sciences
Among the post-translational modifications of proteins, ADP-ribosylation has been studied for over fifty years, and a large set of functions, including DNA repair, transcription, and cell signaling, have been assigned to this post-translational modif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2a67b79943eed924af1e5d6620eab66
https://doi.org/10.3390/ijms221910829
https://doi.org/10.3390/ijms221910829
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