Actin cytoskeleton differently regulates cell surface organization of GPI-anchored proteins in polarized epithelial cells and fibroblasts

Autor: Stéphanie Lebreton, Simona Paladino, Mickaël Lelek, Marc Tramier, Christophe Zimmer, Chiara Zurzolo

Publikováno v: Frontiers in Molecular Biosciences, Vol 11 (2024)

The spatiotemporal compartmentalization of membrane-associated glycosylphosphatidylinositol-anchored proteins (GPI-APs) on the cell surface regulates their biological activities. These GPI-APs occupy distinct cellular functions such as enzymes, recep

Externí odkaz: https://doaj.org/article/9fa0b161e643413bbf6e4506620c1af9

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Extracellular Calcium Acts as a "Third Messenger" to Regulate Enzyme and Alkaline Secretion

Autor: Caroppo, Rosa, Gerbino, Andrea, Fistetto, Gregorio, Colella, Matilde, Debellis, Lucantonio, Hofer, Aldebaran M., Curci, Silvana

Publikováno v: The Journal of Cell Biology, 2004 Jul 01. 166(1), 111-119.

Externí odkaz: https://www.jstor.org/stable/1622224

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Calcium levels in the Golgi complex regulate clustering and apical sorting of GPI-APs in polarized epithelial cells

Autor: Julia von Blume, Maria Nitti, Stéphanie Lebreton, Dandan Liu, Chiara Zurzolo, Simona Paladino, Paolo Pinton

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2021, 118 (33), pp.e2014709118. ⟨10.1073/pnas.2014709118⟩
Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (33), pp.e2014709118. ⟨10.1073/pnas.2014709118⟩
Proc Natl Acad Sci U S A

International audience; Glycosylphosphatidylinositol-anchored proteins (GPI-APs) are lipid-associated luminal secretory cargoes selectively sorted to the apical surface of the epithelia where they reside and play diverse vital functions. Cholesterol-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da1cfa4878e77e0b1d36f0524f7f4ca2
https://hal-pasteur.archives-ouvertes.fr/pasteur-03517396