Zobrazeno 1 - 10
of 285
pro vyhledávání: '"platform trial"'
Autor:
McLeod C, Dymock M, Flanagan KL, Plebanski M, Marshall H, Marsh J, Estcourt MJ, Ramsay J, Wadia U, Williams PCM, Tjiam MC, Blyth C, Subbarao K, Nicholson S, Faust S.N., Thornton RB, Mckenzie A, Snelling T, Richmond P
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-10 (2024)
Abstract Background Coronavirus-2019 (COVID-19) vaccination in Australia commenced in February 2021. The first vaccines recommended for use were AZD1222 and BNT162b2, both delivered as a two-dose primary schedule. In the absence of sustained immunity
Externí odkaz:
https://doaj.org/article/bf1529a9360c49c191e21caa73f4ccfa
Autor:
Kim May Lee, Richard Emsley
Publikováno v:
BMC Medical Research Methodology, Vol 24, Iss 1, Pp 1-18 (2024)
Abstract Background A platform trial approach allows adding arms to on-going trials to speed up intervention discovery programs. A control arm remains open for recruitment in a platform trial while intervention arms may be added after the onset of th
Externí odkaz:
https://doaj.org/article/1410e6b13c5648e6a35bfe9c638348af
Autor:
Jacques Demotes, Victoria Charlotte Simensen, Keiko Ueda, Sareema Javaid, Paula Garcia, Burç Aydin, John-Arne Røttingen
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-5 (2024)
Abstract To ensure optimal coordination of the EU-funded COVID-19 platform trials, a double coordination mechanism was established. It included the Trial Coordination Board (TCB) to promote the dialogue between investigators and relevant public healt
Externí odkaz:
https://doaj.org/article/dfbb9e4afe8d4e2fb6376ef5479f474b
Autor:
Geoerger, Birgit a, b, ⁎, 1, Bautista, Francisco c, d, 1, André, Nicolas e, f, g, Berlanga, Pablo a, Gatz, Susanne A. h, Marshall, Lynley V. i, Rubino, Jonathan j, Archambaud, Baptiste k, l, Marchais, Antonin a, b, Rubio-San-Simón, Alba c, Ducassou, Stephane m, Zwaan, C. Michel d, n, Casanova, Michela o, Nysom, Karsten p, Pellegrino, Sophie j, Hoog-Labouret, Natalie q, Buzyn, Agnes q, Blanc, Patricia r, Paoletti, Xavier k, l, 2, 3, Vassal, Gilles a, j, 3
Publikováno v:
In European Journal of Cancer September 2024 208
Publikováno v:
Xiehe Yixue Zazhi, Vol 15, Iss 5, Pp 1157-1164 (2024)
Adaptive design, with advantages such as dynamically adjusting trial plans, reducing resource waste, and improving trial efficiency, has broken through the competitive situation of new drug development and gradually met the needs of clinical research
Externí odkaz:
https://doaj.org/article/f7ef88732498479eb03aa9c95879b123
Autor:
Barrett, Jeffrey S. a, ⁎, Lasater, Kara a, Russell, Scott a, McCune, Susan b, Miller, Timothy M. c, Sibbald, David a
Publikováno v:
In Contemporary Clinical Trials July 2024 142
Autor:
Chaudhuri, Shomesh E. a, Lo, Andrew W. a, b, c, d, e, ⁎
Publikováno v:
In Journal of Econometrics March 2024 240(2)
Autor:
Athanasios Saratzis
Publikováno v:
NIHR Open Research, Vol 4 (2024)
Background Peripheral artery disease (PAD) is a common health problem. There are several technologies, medications, and interventions that aim to improve or treat PAD in people with symptomatic disease. Most of these technologies, however, have been
Externí odkaz:
https://doaj.org/article/0fc4c240a38847489842304b88aaa5d0
Autor:
C. McLeod, J Ramsay, K. L. Flanagan, M. Plebanski, H. Marshall, M. Dymock, J. Marsh, M. J. Estcourt, U. Wadia, P. C. M. Williams, M. C. Tjiam, C. Blyth, K. Subbarao, S. Nicholson, S. Faust, R. B. Thornton, A. Mckenzie, T. L Snelling, P. Richmond
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-14 (2023)
Abstract Background The need for coronavirus 2019 (COVID-19) vaccination in different age groups and populations is a subject of great uncertainty and an ongoing global debate. Critical knowledge gaps regarding COVID-19 vaccination include the durati
Externí odkaz:
https://doaj.org/article/6d837e182ed84c918b3162dfc80d7663
Autor:
Richard A. Parker, Christopher J. Weir, Tra My Pham, Ian R. White, Nigel Stallard, Mahesh K. B. Parmar, Robert J. Swingler, Rachel S. Dakin, Suvankar Pal, Siddharthan Chandran
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-15 (2023)
Abstract Background MND-SMART is a platform, multi-arm, multi-stage, multi-centre, randomised controlled trial recruiting people with motor neuron disease. Initially, the treatments memantine and trazodone will each be compared against placebo, but o
Externí odkaz:
https://doaj.org/article/79ee44339d2044749471abb674bbc6f1