Zobrazeno 1 - 10
of 820
pro vyhledávání: '"platelet-activating factor receptor"'
Autor:
Mai H. Tu, Timothy M. Brenza, Margaret R. Ketterer, Morgan Timm, Benjamin M. King, Michael A. Apicella, Jennifer Fiegel
Publikováno v:
KONA Powder and Particle Journal, Vol 41, Iss 0, Pp 265-279 (2023)
Several bacterial pathogens contain membrane ligands that facilitate their binding and internalization into human tissues. In this study, lipooligosaccharides (LOS) from the respiratory pathogen non-typeable Haemophilus influenzae (NTHi) were isolate
Externí odkaz:
https://doaj.org/article/ed0617b1c04747a4947da5999904bc4d
Akademický článek
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Publikováno v:
Zhongguo aizheng zazhi, Vol 31, Iss 11, Pp 1063-1071 (2021)
Background and purpose: The current treatment of ovarian cancer is surgery and adjuvant platinum-based chemotherapy. However, relapse and drug resistance are common. We have demonstrated the platelet-activating factor receptor (PAFR) is highly expres
Externí odkaz:
https://doaj.org/article/f64cb57c5f3b46e8ad30fa70ce5c1147
Autor:
Tingting Li, Xuebin Zhang, Ping Jiang, Dandan Zhang, Luda Feng, Xinxing Lai, Mingzhen Qin, Yufei Wei, Chi Zhang, Ying Gao
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: Acute ischemic stroke (AIS) is a common cause of death and long-term disability worldwide. Recent trials of platelet-activating factor receptor antagonists (PAFRA) appeared to indicate that they could play a neuroprotective role in the tr
Externí odkaz:
https://doaj.org/article/276fa0459be94be0a449f7e51c6bff80
Autor:
Timothy C. Frommeyer, Michael M. Gilbert, Garrett V. Brittain, Tongfan Wu, Trang Q. Nguyen, Craig A. Rohan, Jeffrey B. Travers
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Ultraviolet B radiation (UVB) has profound effects on human skin that results in a broad spectrum of immunological local and systemic responses and is the major cause of skin carcinogenesis. One important area of study in photobiology is how UVB is t
Externí odkaz:
https://doaj.org/article/e17f317b5c8349bc814e2522392de584
Autor:
Rajendran Harishkumar, Sakshi Hans, Janelle E. Stanton, Andreas M. Grabrucker, Ronan Lordan, Ioannis Zabetakis
Publikováno v:
Nutrients, Vol 14, Iss 20, p 4414 (2022)
Platelet-activating factor (PAF) is a lipid mediator that interacts with its receptor (PAF-R) to carry out cell signalling. However, under certain conditions the binding of PAF to PAF-R leads to the activation of pro-inflammatory and prothrombotic pa
Externí odkaz:
https://doaj.org/article/e70bafaf36094aeaaf1a748ae0499eac
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 109, Iss , Pp 563-572 (2019)
Gemcitabine resistance will occur by time after the initial response in pancreatic cancer. Ginkgolide B (GB), a major terpene lactone component of Ginkgo biloba leaves, is a highly selective and competitive inhibitor for platelet-activating factor (P
Externí odkaz:
https://doaj.org/article/d3a95f09cb9043238f3f4f4cc04cce64
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 12, p 6772 (2022)
Accumulating evidence indicates that microRNAs (miRs) play critical roles in essentially all biological processes and their altered expression has been documented in various disease conditions, including human malignancies. Although several cellular
Externí odkaz:
https://doaj.org/article/13d3bea03cad447cb79564d724151a78
Autor:
Juliana L. Souza, Karina Martins-Cardoso, Isabella S. Guimarães, Andréia C. de Melo, Angela H. Lopes, Robson Q. Monteiro, Vitor H. Almeida
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase widely expressed in cervical tumors, being correlated with adverse clinical outcomes. EGFR may be activated by a diversity of mechanisms, including transactivation by G-protein cou
Externí odkaz:
https://doaj.org/article/9d1afa614c9e44bc82930f3dbfc63e8a
Akademický článek
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