Zobrazeno 1 - 10
of 644
pro vyhledávání: '"platelet-activating factor (paf)"'
Publikováno v:
Journal of Pharmacological Sciences, Vol 152, Iss 2, Pp 123-127 (2023)
We investigated the extracellular Ca2+ influx pathways involved in platelet-activating factor (PAF)-enhanced guinea pig detrusor smooth muscle (DSM) contractile activities. One micromolar PAF-enhanced DSM contractile activities were completely inhibi
Externí odkaz:
https://doaj.org/article/242bc75c9e154105a529975958df74e2
Autor:
Cliodhna Caffrey, Anna Leamy, Ellen O’Sullivan, Ioannis Zabetakis, Ronan Lordan, Constantina Nasopoulou
Publikováno v:
Marine Drugs, Vol 21, Iss 11, p 549 (2023)
Cardiovascular diseases (CVD) remain the leading cause of death across the globe, hence, establishing strategies to counteract CVD are imperative to reduce mortality and the burden on health systems. Dietary modification is an effective primary preve
Externí odkaz:
https://doaj.org/article/136b3d75de254ed5b621c357e02d72f9
Autor:
Mohammed BOUACHRINE, Larbi Elmchichi, Abdellah El Aissouq, Assia BELHASSAN, Hanane Zaki, Abdelkrim Ouammou, Tahar Lakhlifi
Publikováno v:
Chemical Review and Letters, Vol 4, Iss 3, Pp 145-152 (2021)
Studies and scientific research indicate that the platelet-activating factor (PAF) is a major pro-inflammatory mediator in the initiation and development of cancer. There is also evidence confirming that PAF is an integral part of suppressing the imm
Externí odkaz:
https://doaj.org/article/5a91c7b43321492694839ff91fb1d1f4
Autor:
Alexandros Kalampalidis, Artemis Damati, Demetrios Matthopoulos, Alexandros B. Tsoupras, Constantinos A. Demopoulos, Gregor Schnakenburg, Athanassios I. Philippopoulos
Publikováno v:
Molecules, Vol 28, Iss 4, p 1859 (2023)
Metal complexes displaying antiplatelet properties is a promising research area. In our methodology, Platelet-Activating Factor (PAF), the most potent lipid pro-inflammatory mediator, serves as a biological probe. The antiplatelet activity is exerted
Externí odkaz:
https://doaj.org/article/3b1e09a6c122454181eac71aa26861ae
Autor:
Valerie A. Cruz Flores, Hemant Menghani, Pranab K. Mukherjee, Luis Marrero, Andre Obenaus, Quan Dang, Larissa Khoutorova, Madigan M. Reid, Ludmila Belayev, Nicolas G. Bazan
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Glioblastoma multiforme (GBM) is an aggressive, highly proliferative, invasive brain tumor with a poor prognosis and low survival rate. The current standard of care for GBM is chemotherapy combined with radiation following surgical intervention, alto
Externí odkaz:
https://doaj.org/article/732ac317fda544328fa7c8739d2506d2
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Described almost 50 years ago, the glycerophosphocholine lipid mediator Platelet-activating factor (PAF) has been implicated in many pathologic processes. Indeed, elevated levels of PAF can be measured in response to almost every type of pathology in
Externí odkaz:
https://doaj.org/article/c327dff67f544de0a5182a3c209c2c2e
Autor:
Filio Petsini, Agathi Ntzouvani, Maria Detopoulou, Vasiliki D Papakonstantinou, Nick Kalogeropoulos, Elizabeth Fragopoulou, Tzortzis Nomikos, Meropi D Kontogianni, Smaragdi Antonopoulou
Publikováno v:
Foods, Vol 11, Iss 14, p 2105 (2022)
A fish-rich diet has a beneficial effect on cardiovascular health. The platelet activating factor (PAF) is involved in the development of atherosclerosis, and in vitro results support the regulating action of bioactive nutrients on PAF metabolism. Th
Externí odkaz:
https://doaj.org/article/64713f0e8bc2422c9fdb485093a9c6c5
Akademický článek
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Autor:
Tong Gao, Yi Yu, Qing Cong, Yisheng Wang, Mingming Sun, Liangqing Yao, Congjian Xu, Wei Jiang
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background The tumour microenvironment conferred by mesenchymal stem cells (MSCs) plays a key role in tumour development and progression. We previously determined that platelet-activating factor receptor (PAFR) was overexpressed in ovarian c
Externí odkaz:
https://doaj.org/article/b5d4fcd0c6f64e688506387441ed2f98
Autor:
Eileen Deuster, Ivi Hysenaj, Maja Kahaly, Elisa Schmoeckel, Doris Mayr, Susanne Beyer, Thomas Kolben, Anna Hester, Fabian Kraus, Anca Chelariu-Raicu, Alexander Burges, Sven Mahner, Udo Jeschke, Fabian Trillsch, Bastian Czogalla
Publikováno v:
Cells, Vol 10, Iss 9, p 2337 (2021)
The platelet-activating factor receptor (PAFR) and its ligand (PAF) are important inflammatory mediators that are overexpressed in ovarian cancer. The receptor is an important player in ovarian cancer development. In this study, we aimed to evaluate
Externí odkaz:
https://doaj.org/article/fcf9a42f48fe4ba7a4a18d1a16d83e37