Coronary plaque composition influences biomechanical stress and predicts plaque rupture in a morpho-mechanic OCT analysis

Autor: Andrea Milzi, Enrico Domenico Lemma, Rosalia Dettori, Kathrin Burgmaier, Nikolaus Marx, Sebastian Reith, Mathias Burgmaier

Publikováno v: eLife, Vol 10 (2021)

Plaque rupture occurs if stress within coronary lesions exceeds the protection exerted by the fibrous cap overlying the necrotic lipid core. However, very little is known about the biomechanical stress exerting this disrupting force. Employing optica

Externí odkaz: https://doaj.org/article/e912e653ca744f2bb05074c4bd7459d4

Coronary plaque composition influences biomechanical stress and predicts plaque rupture in a morpho-mechanic OCT analysis.

Autor: Milzi A; Department of Cardiology, University Hospital of the RWTH Aachen, Aachen, Germany., Lemma ED; Zoological Institute, Department of Cell- and Neurobiology, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany., Dettori R; Department of Cardiology, University Hospital of the RWTH Aachen, Aachen, Germany., Burgmaier K; Department of Pediatrics, University Hospital of Cologne, Cologne, Germany., Marx N; Department of Cardiology, University Hospital of the RWTH Aachen, Aachen, Germany., Reith S; Department of Cardiology, University Hospital of the RWTH Aachen, Aachen, Germany., Burgmaier M; Department of Cardiology, University Hospital of the RWTH Aachen, Aachen, Germany.

Publikováno v: ELife [Elife] 2021 May 11; Vol. 10. Date of Electronic Publication: 2021 May 11.