Zobrazeno 1 - 10
of 2 010
pro vyhledávání: '"plakoglobin"'
Autor:
Chu Shiun Lo, Sara Ibrahim Omar, Jinlan Chang, Blessing Bassey-Archibong, Jack A Tuszynski, Nadia Jahroudi, Manijeh Pasdar
Publikováno v:
Re:GEN Open, Vol 3, Iss 1, Pp 40-51 (2023)
Background: The conformational p53-R175H is the most frequently occurring p53 mutant in cancers and a focus of mutant p53 targeted therapies. Plakoglobin is a dual cell adhesion and signaling protein with tumor suppressor activity. We previously show
Externí odkaz:
https://doaj.org/article/bd71a0ad83ac407888f30f165dbb77bf
Autor:
Lijuan Yin, Qinlong Li, Stefan Mrdenovic, Gina Chia-Yi Chu, Boyang Jason Wu, Hong Bu, Peng Duan, Jayoung Kim, Sungyong You, Michael S. Lewis, Gangning Liang, Ruoxiang Wang, Haiyen E. Zhau, Leland W. K. Chung
Publikováno v:
Breast Cancer Research, Vol 24, Iss 1, Pp 1-13 (2022)
Abstract Background Keratins (KRTs) are intermediate filament proteins that interact with multiple regulatory proteins to initiate signaling cascades. Keratin 13 (KRT13) plays an important role in breast cancer progression and metastasis. The objecti
Externí odkaz:
https://doaj.org/article/81fdffabdd8947c88d1526d072f838ac
Autor:
Tanja Spethmann, Lukas Clemens Böckelmann, Vera Labitzky, Ann‐Kristin Ahlers, Jennifer Schröder‐Schwarz, Sarah Bonk, Ronald Simon, Guido Sauter, Hartwig Huland, Robert Kypta, Udo Schumacher, Tobias Lange
Publikováno v:
Molecular Oncology, Vol 15, Iss 7, Pp 1956-1969 (2021)
Both oncogenic and tumor suppressor functions have been described for junction plakoglobin (JUP), also known as γ‐catenin. To clarify the role of JUP in prostate cancer, JUP protein expression was immunohistochemically detected in a tissue microar
Externí odkaz:
https://doaj.org/article/7121450caf7b4f2591affd5fcf9ae787
Autor:
Ke Chen, Jin Zeng, Yi Sun, Wei Ouyang, Gan Yu, Hui Zhou, Yangjun Zhang, Weimin Yao, Wei Xiao, Junhui Hu, Jinchun Xing, Kefeng Xiao, Lily Wu, Zhiqiang Chen, Zhangqun Ye, Hua Xu
Publikováno v:
Cancer Communications, Vol 41, Iss 4, Pp 316-332 (2021)
Abstract Background Increased hypoxia‐inducible factor 2α (HIF2α) activation is a common event in clear cell renal cell carcinoma (ccRCC) progression. However, the function and underlying mechanism of HIF2α in ccRCC remains uninvestigated. We co
Externí odkaz:
https://doaj.org/article/2c1c02164eec437c8f8d7e84e819d8f3
Autor:
Carlos Bueno-Beti, Angeliki Asimaki
Publikováno v:
Biomedicines, Vol 11, Iss 4, p 1207 (2023)
Arrhythmogenic cardiomyopathy (ACM) is a heart muscle disease associated with ventricular arrhythmias and a high risk of sudden cardiac death (SCD). Although the disease was described over 40 years ago, its diagnosis is still difficult. Several studi
Externí odkaz:
https://doaj.org/article/cc24209f17f84048b832b85408144a47
Autor:
Jean-Marc Good, MD, PhD, Florence Fellmann, MD, PhD, Zahurul A. Bhuiyan, MBBS, PhD, FESC, Samuel Rotman, MD, Etienne Pruvot, MD, Jürg Schläpfer, MD
Publikováno v:
HeartRhythm Case Reports, Vol 6, Iss 1, Pp 15-19 (2020)
Externí odkaz:
https://doaj.org/article/56a878ac48144045a6219df4375b5d36
Akademický článek
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Akademický článek
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Autor:
Florian Weiland, Noor A. Lokman, Manuela Klingler-Hoffmann, Thomas Jobling, Andrew N. Stephens, Karin Sundfeldt, Peter Hoffmann, Martin K. Oehler
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Ovarian cancer is the most lethal gynecologic malignancy. Early detection would improve survival, but an effective diagnostic test does not exist. Novel biomarkers for early ovarian cancer diagnosis are therefore warranted. We performed intraoperativ
Externí odkaz:
https://doaj.org/article/e688cee0f3b749709580f0d24b9e20f1
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 13, Iss 1, Pp 1-11 (2018)
Abstract Naxos disease, first described by Dr. Nikos Protonotarios and colleagues on the island of Naxos, Greece, is a special form of arrhythmogenic right ventricular dysplasia (ARVD). It is an inherited condition with a recessive form of transmissi
Externí odkaz:
https://doaj.org/article/a4bc2b0d50134e77840c90b1a2a09c6e