Zobrazeno 1 - 10
of 519
pro vyhledávání: '"pilsicainide"'
Publikováno v:
Clinical Case Reports, Vol 11, Iss 6, Pp n/a-n/a (2023)
Key Clinical Message A 22‐year‐old male presented to our hospital after receiving 2450 mg of pilsicainide hydrochloride. Subsequently, he experienced cardiac arrest, and percutaneous cardiopulmonary support was introduced to maintain his circulat
Externí odkaz:
https://doaj.org/article/1756ba9a53b94fca998a269f04236d5f
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
We present a fatal case of pilsicainide poisoning. Quantitative toxicological analysis revealed that the concentrations of pilsicainide in femoral blood and urine samples were 17.5 μg/mL and 136.9 μg/mL, respectively. No morphological changes due t
Externí odkaz:
https://doaj.org/article/05ec86395c7b4962a9d781828f09eba9
Akademický článek
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Autor:
Ryuichi Kambayashi, Hiroko Izumi-Nakaseko, Ai Goto, Kazuya Tsurudome, Hironori Ohshiro, Taku Izumi, Mihoko Hagiwara-Nagasawa, Koki Chiba, Ryota Nishiyama, Satomi Oyama, Yoshio Nunoi, Yoshinori Takei, Akio Matsumoto, Atsushi Sugiyama
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Oseltamivir has been shown to prolong the atrial conduction time and effective refractory period, and to suppress the onset of burst pacing-induced atrial fibrillation in vitro. To better predict its potential clinical benefit as an anti-atrial fibri
Externí odkaz:
https://doaj.org/article/1a13bc521af8454eaaeab2711091b51a
Autor:
Tsuyoshi Shiga, Koichiro Yoshioka, Eiichi Watanabe, Hisako Omori, Masahiro Yagi, Yasuo Okumura, Naoki Matsumoto, Kengo Kusano, Chikara Oshiro, Takanori Ikeda, Naohiko Takahashi, Takashi Komatsu, Atsushi Suzuki, Tsuyoshi Suzuki, Yasuto Sato, Takeshi Yamashita
Publikováno v:
Journal of Arrhythmia, Vol 33, Iss 4, Pp 310-317 (2017)
Background: The therapeutic goals of atrial fibrillation (AF) patients are to reduce symptoms and prevent severe complications associated with AF. This study compared the efficacy of flecainide versus pilsicainide in reducing the frequency of AF and
Externí odkaz:
https://doaj.org/article/f55094006f3244b39efbae0cf2794101
Autor:
Takeshi Onohara, MD, Ichiro Hisatome, MD, Yasutaka Kurata, MD, Peili Li, MD, Tomomi Notsu, PhD, Kumi Morikawa, PhD, Naoyuki Otani, MD, Akio Yoshida, MD, Kazuhiko Iitsuka, MD, Masaru Kato, MD, Junichiro Miake, MD, Haruaki Ninomiya, MD, Katsumi Higaki, PhD, Yasuaki Shirayoshi, PhD, Takashi Nishihara, BE, Toshiyuki Itoh, PhD, Yoshinobu Nakamura, MD, Motonobu Nishimura, MD
Publikováno v:
Journal of Arrhythmia, Vol 33, Iss 3, Pp 226-233 (2017)
Background: Pilsicainide, classified as a relatively selective Na+ channel blocker, also has an inhibitory action on the rapidly-activating delayed-rectifier K+ current (IKr) through human ether-a-go-go-related gene (hERG) channels. We studied the ef
Externí odkaz:
https://doaj.org/article/79c1cda0789f496394eafca2f1b97d00
Autor:
Suchitra Matsukura, Yuji Nakamura, Xin Cao, Takeshi Wada, Hiroko Izumi-Nakaseko, Kentaro Ando, Hiroshi Yamazaki, Atsushi Sugiyama
Publikováno v:
Journal of Pharmacological Sciences, Vol 133, Iss 2, Pp 103-109 (2017)
We pharmacologically characterized microminipigs as an in vivo experimental model by assessing cardiovascular effects of pilsicainide, verapamil and E-4031, which can preferentially inhibit cardiac Na+, Ca2+ and K+ channels, respectively. Intravenous
Externí odkaz:
https://doaj.org/article/2b67043284f54d62bdc345c0b7f0d62e
Autor:
Hisaaki Aoki, MD, PHD, Yoshihide Nakamura, MD, Seiko Ohno, MD, PHD, Takeru Makiyama, MD, PHD, Minoru Horie, MD, PHD
Publikováno v:
Journal of Arrhythmia, Vol 33, Iss 1, Pp 35-39 (2017)
Background: Phenotypes often differ even within family members carrying the same SCN5A mutation. We aimed to evaluate the genetic modifiers in a family with Brugada syndrome (BrS) and sick sinus syndrome (SSS) with an SCN5A mutation that causes the t
Externí odkaz:
https://doaj.org/article/7001ba9ef1f24f298cb74578c7946a38
Autor:
Hideki Koike, MD, Tadashi Fujino, MD, PhD, Makiko Koike, MD, Shintaro Yao, MD, Masaya Shinohara, MD, Ken Kitahara, MD, PhD, Toshio Kinoshita, MD, PhD, Hitomi Yuzawa, MD, Takeya Suzuki, MD, PhD, Hideyuki Sato, MD, Shunji Fukunaga, MD, Kenzaburo Kobayashi, MD, PhD, Takanori Ikeda, MD, PhD, FJCC
Publikováno v:
Journal of Arrhythmia, Vol 32, Iss 6, Pp 468-473 (2016)
Background: Pilsicainide, a pure Na+ channel blocker, is a popular antiarrhythmic drug for the management of atrial tachyarrhythmias (AT), in Japan. However, serious drug-induced proarrhythmias (DIPs) may unexpectedly occur. We assessed the clinical
Externí odkaz:
https://doaj.org/article/43cbbdaa98f446dd8807e930aac87b41
Akademický článek
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