Zobrazeno 1 - 10
of 601
pro vyhledávání: '"pik3r1"'
Autor:
Arnault Tauziède-Espariat, Lelio Guida, Volodia Dangouloff-Ros, Nathalie Boddaert, Gaëlle Pierron, Delphine Guillemot, Julien Masliah-Planchon, Lauren Hasty, Alice Métais, Fabrice Chrétien, Pascale Varlet
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-5 (2024)
Abstract A novel histomolecular tumor of the central nervous system (CNS), the “diffuse glioneuronal tumor with oligodendroglioma-like features and nuclear clusters (DGONC),” has recently been identified, based on a distinct DNA methylation profi
Externí odkaz:
https://doaj.org/article/1551acb744574bdcb474f9ef64e5f429
Publikováno v:
COPD, Vol 21, Iss 1 (2024)
Purpose Chronic Obstructive Pulmonary Disease (COPD) is regarded as an accelerated aging disease. Aging-related genes in COPD are still poorly understood.Method Data set GSE76925 was obtained from the Gene Expression Omnibus (GEO) database. The “li
Externí odkaz:
https://doaj.org/article/9ea7c02a2c69436fb34dbd876ef87fd5
Autor:
Han Li, Run Lin, Yanna Zhang, Yanni Zhu, Shuting Huang, Jing Lan, Nian Lu, Chuanmiao Xie, Shanyang He, Weijing Zhang
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-19 (2024)
Abstract Background Cisplatin (CDDP) is the first-line chemotherapeutic strategy to treat patients with ovarian cancer (OC). The development of CDDP resistance remains an unsurmountable obstacle in OC treatment and frequently induces tumor recurrence
Externí odkaz:
https://doaj.org/article/a1dd0367304b4c3db2fa89380be1e097
Publikováno v:
Journal of Advanced Biotechnology and Experimental Therapeutics, Vol 6, Iss 2, Pp 375-385 (2023)
Background: Gastric cancer (GC), which is the fourth most prevalent cancer in the world is significantly threatened the health of people, particularly those in developing nations. Nearly all significant pathological and physiological mechanisms, incl
Externí odkaz:
https://doaj.org/article/81a9fa6b1b374f1b91fa93dd0b4cc71d
Autor:
T. V. Ivanenko
Publikováno v:
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, Vol 16, Iss 2, Pp 154-157 (2023)
The development and progression of diabetes involves several molecular mechanisms, in particular: insulin resistance, dysfunction of beta cells, inflammatory processes. These mechanisms can disrupt insulin signaling pathways, contribute to beta-cell
Externí odkaz:
https://doaj.org/article/55949bf2ce74470db160234546374e90
Autor:
Matheus V. M. B. Wilke, Lisa Schimmenti, Madeline Q. R. Lopour, Megha M. Tollefson, Eric W. Klee
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 11, Iss 12, Pp n/a-n/a (2023)
Abstract Background The PI3K/AKT pathway, extensively studied in cancer, is vital for regulating cell metabolism, differentiation, and proliferation. Pathogenic variants in the PIK3R1 gene, which encodes three regulatory units of class IA PI3Ks, have
Externí odkaz:
https://doaj.org/article/2b2a2d0ea75b48b8b7e22a61fb5d289f
Autor:
Hisham F. Bahmad, Gina Elhammady, Jennifer M. Gass, Juan C. Paramo, Robert Poppiti, John Alexis
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 2, Pp 954-962 (2023)
Sclerosing polycystic adenoma (SPA) is a rare neoplasm occurring in the salivary glands, mainly the parotid gland. Although it was originally thought to represent a non-neoplastic process, recent genetic data have proven its monoclonality, supporting
Externí odkaz:
https://doaj.org/article/95e1b26a8efe45de948b619c5de4dc4d
Akademický článek
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Akademický článek
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Publikováno v:
Open Medicine, Vol 17, Iss 1, Pp 847-856 (2022)
Our previous study has demonstrated that miR-455-5p was a tumor suppressor in colorectal cancer (CRC). This study aimed to investigate the role of miR-455-5p in 5-fluorouracil (5-Fu) in CRC. The expression of miR-455-5p, PIK3R1, and DEPDC1 was analyz
Externí odkaz:
https://doaj.org/article/f888f085d615477dbab2987db341af0c