Zobrazeno 1 - 10
of 15
pro vyhledávání: '"physiopathology [Neural Pathways]"'
Autor:
Marc Tittgemeyer, Carsten Eggers, Sophie Stürmer, Masoud Tahmasian, Andrea Greuel, Franziska Maier, Lars Timmermann, Frank L. Schwartz, Jochen Hammes, Marina C. Ruppert, Thilo van Eimeren, Alexander Drzezga
Publikováno v:
Brain 143(3), 944-959 (2020). doi:10.1093/brain/awaa019
The spreading hypothesis of neurodegeneration assumes an expansion of neural pathologies along existing neural pathways. Multimodal neuroimaging studies have demonstrated distinct topographic patterns of cerebral pathologies in neurodegeneration. For
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dccbcb52ca736332c88200fde51bf533
https://doi.org/10.1093/brain/awaa019
https://doi.org/10.1093/brain/awaa019
Autor:
Roxanne Lofredi, Wolf-Julian Neumann, Friederike Irmen, Johanna Nieweler, Gerd-Helge Schneider, Georg Cem Auernig, Andrea A. Kühn, Andreas Horn
Publikováno v:
Brain 144(1), 44-52 (2021). doi:10.1093/brain/awaa341
The subthalamic nucleus is part of a global stopping network that also includes the presupplementary motor area and inferior frontal gyrus of the right hemisphere. In Parkinson’s disease, subthalamic deep brain stimulation improves movement initiat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36ccbda96901ac1cf13609fa85400e30
https://pub.dzne.de/record/155618
https://pub.dzne.de/record/155618
Autor:
Cavedo, Enrica, Chiesa, Patrizia A., Houot, Marion, Ferretti, Maria Teresa, Grothe, Michel J., Teipel, Stefan J., Lista, Simone, Habert, Marie-Odile, Potier, Marie-Claude, Dubois, Bruno, Hampel, Harald, Bakardjian, Hovagim, Benali, Habib, Bertin, Hugo, Bonheur, Joel, Boukadida, Laurie, Boukerrou, Nadia, Chiesa, Patrizia, Colliot, Olivier, Dubois, Marion, Epelbaum, Stéphane, Gagliardi, Geoffroy, Genthon, Remy, Kas, Aurélie, Lamari, Foudil, Levy, Marcel, Metzinger, Christiane, Mochel, Fanny, Nyasse, Francis, Poisson, Catherine, Revillon, Marie, Santos, Antonio, Andrade, Katia Santos, Sole, Marine, Surtee, Mohmed, de Schotten, Michel Thiebaud, Vergallo, Andrea, Younsi, Nadjia, Aguilar, Lisi Flores, Babiloni, Claudio, Baldacci, Filippo, Benda, Norbert, Black, Keith L., Bokde, Arun L. W., Bonuccelli, Ubaldo, Broich, Karl, Bun, René S., Cacciola, Francesco, Castrillo, Juan, Ceravolo, Roberto, Coman, Cristina-Maria, Corvol, Jean-Christophe, Cuello, Augusto Claudio, Cummings, Jeffrey L., Depypere, Herman, Duggento, Andrea, Durrleman, Stanley, Escott-Price, Valentina, Federoff, Howard, Fiandaca, Massimo, Frank, Richard A., Garaci, Francesco, George, Nathalie, Giorgi, Filippo S., Graziani, Manuela, Haberkamp, Marion, Herholz, Karl, Karran, Eric, Kim, Seung H., Koronyo, Yosef, Koronyo-Hamaoui, Maya, Langevin, Todd, Lehéricy, Stéphane, Lorenceau, Jean, Mapstone, Mark, Neri, Christian, Nisticò, Robert, Nyasse-Messene, Francis, O'Bryant, Sid E., Perry, George, Ritchie, Craig, Rojkova, Katrine, Rossi, Simone, Saidi, Amira, Santarnecchi, Emiliano, Schneider, Lon S., Sporns, Olaf, Toschi, Nicola, Verdooner, Steven R., Villain, Nicolas, Welikovitch, Lindsay A., Woodcock, Janet, Younesi, Erfan
Publikováno v:
Alzheimer's and dementia 14(9), 1204-1215 (2018). doi:10.1016/j.jalz.2018.05.014
Observational multimodal neuroimaging studies indicate sex differences in Alzheimer's disease pathophysiological markers.Positron emission tomography brain amyloid load, neurodegeneration (hippocampus and basal forebrain volumes adjusted to total int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b37777bed288ac4e99e1c4a104124ca
https://doi.org/10.1016/j.jalz.2018.05.014
https://doi.org/10.1016/j.jalz.2018.05.014
Autor:
Richard Du, Theresa M. Harrison, William J. Jagust, Jenna N. Adams, Anne Maass, Suzanne L. Baker
Publikováno v:
Nature communications, vol 10, iss 1
Nature Communications 10(1), 4900 (2019). doi:10.1038/s41467-019-12921-z
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications
Nature Communications 10(1), 4900 (2019). doi:10.1038/s41467-019-12921-z
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications
The tau protein aggregates in aging and Alzheimer disease and may lead to memory loss through disruption of medial temporal lobe (MTL)-dependent memory systems. Here, we investigated tau-mediated mechanisms of hippocampal dysfunction that underlie th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5883d88128dbc4ded7a9899152d29201
https://escholarship.org/uc/item/3sb5s3zv
https://escholarship.org/uc/item/3sb5s3zv
Publikováno v:
Brain 142(8), 2198-2206 (2019). doi:10.1093/brain/awz152
The basal ganglia and cerebellum are implicated in both motor learning and Parkinson’s disease. Deep brain stimulation (DBS) is an established treatment for advanced Parkinson’s disease that leads to motor and non-motor effects by modulating spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e11c09965f9a2e7d267274e594884d3c
https://pub.dzne.de/record/141481
https://pub.dzne.de/record/141481
Autor:
Mihalik, Agoston, Ferreira, Fabio S, Kitzbichler, Manfred G, Váša, František, Vaghi, Matilde M, Bullmore, Edward T, Fonagy, Peter, Goodyer, Ian M, Jones, Peter B, Consortium, NSPN, Dolan, Raymond, Mourão-Miranda, Janaina, Rosa, Maria J, Hauser, Tobias, Neufeld, Sharon, Clair, Michelle St, Whitaker, Kirstie, Inkster, Becky, Prabhu, Gita, Ooi, Cinly, Toseeb, Umar, Widmer, Barry, Bhatti, Junaid, Moutoussis, Michael, Villis, Laura, Alrumaithi, Ayesha, Birt, Sarah, Bowler, Aislinn, Cleridou, Kalia, Dadabhoy, Hina, Davies, Emma, Firkins, Ashlyn, Granville, Sian, Harding, Elizabeth, Ziegler, Gabriel, Hopkins, Alexandra, Isaacs, Daniel, King, Janchai, Kokorikou, Danae, Maurice, Christina, McIntosh, Cleo, Memarzia, Jessica, Mills, Harriet, O'Donnell, Ciara, Pantaleone, Sara, Monteiro, Joao M, Scott, Jenny, Fearon, Pasco, Suckling, John, van Harmelen, Anne-Laura, Kievit, Rogier, Portugal, Liana, Adams, Rick A, Romero-Garcia, Rafael, Vértes, Petra E
Publikováno v:
Scientific Reports
Scientific reports 9(1), 11536 (2019). doi:10.1038/s41598-019-47277-3
Scientific reports 9(1), 11536 (2019). doi:10.1038/s41598-019-47277-3
Understanding how variations in dimensions of psychometrics, IQ and demographics relate to changes in brain connectivity during the critical developmental period of adolescence and early adulthood is a major challenge. This has particular relevance f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbd97b74c504bd9836ae88e39893eae8
https://hdl.handle.net/21.11116/0000-0004-A632-8
https://hdl.handle.net/21.11116/0000-0004-A632-8
Autor:
Daniel Weiss, Marlieke Scholten, Georgios Naros, Alireza Gharabaghi, Ander Ramos-Murguialday, Friedemann Bunjes, Rejko Krüger, Rosa Klotz, Rathinaswamy B. Govindan, Christian Plewnia, Christoph Meisner
Publikováno v:
Brain
Brain 138(3), 679-693 (2015). doi:10.1093/brain/awu380
Brain 138(3), 679-693 (2015). doi:10.1093/brain/awu380
Dynamic modulations of large-scale network activity and synchronization are inherent to a broad spectrum of cognitive processes and are disturbed in neuropsychiatric conditions including Parkinson's disease. Here, we set out to address the motor netw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d95ebf3633bc45bd9d522c19e0e0509
https://doi.org/10.1093/brain/awu380
https://doi.org/10.1093/brain/awu380
Publikováno v:
The lancet / Psychiatry 4(10), 768-774 (2017). doi:10.1016/S2215-0366(17)30330-9
Summary Background In anti-NMDA receptor (NMDAR) encephalitis, antibody-mediated dysfunction of NMDARs causes severe neuropsychiatric symptoms, including psychosis, memory deficits, and movement disorders. However, it remains elusive how antibody-med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b8ab9bc7fb5e182d3c32cbaf3cf25a1
https://pubmed.ncbi.nlm.nih.gov/29277216
https://pubmed.ncbi.nlm.nih.gov/29277216
Autor:
Stefan J. Teipel, Karlheinz Hauenstein, Steffi Webel, Sina Ochmann, Michel J. Grothe, Martin Dyrba, Elisabeth Kasper
Publikováno v:
Journal of Alzheimer's Disease
Journal of Alzheimer's disease 57(4), 1303-1313 (2017). doi:10.3233/JAD-160773
Journal of Alzheimer's disease 57(4), 1303-1313 (2017). doi:10.3233/JAD-160773
Background: Cognitive rehabilitation (CR) is a cognitive intervention for patients with Alzheimer’s disease (AD) that aims to maintain everyday competences. The analysis of functional connectivity (FC) in resting-state functional MRI has been used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41a0df9bd61edfb755c9dbd9aa7e9562
https://pubmed.ncbi.nlm.nih.gov/28372326
https://pubmed.ncbi.nlm.nih.gov/28372326
Autor:
Michel J. Grothe, Martin Scherr, Igor Yakushev, Christian Sorg, Gloria Benson, Lukas Utz, Nicholas E. Myers, Timo Grimmer, Lorenzo Pasquini
Publikováno v:
Journal of Alzheimer's disease 58(3), 763-773 (2017). doi:10.3233/JAD-170096
In Alzheimer's disease (AD), amyloid-β (Aβ) pathology and intrinsic functional connectivity (iFC) interact. Across stages of AD, we expected individual spatial correspondence of Aβ and iFC to reveal both Aβ accumulation and its detrimental effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a376401b64a403b625cdc4b6ac7dbe83