Zobrazeno 1 - 3
of 3
pro vyhledávání: '"physiology [Ubiquitin-Protein Ligases]"'
Autor:
Karina Kloos, Christian Haass, Frank Vogel, Kerstin Lämmermann, Andreas S. Reichert, Lena Bouman, Julia S. Schlehe, Bettina Brunner, Wolfgang Wurst, Annerose Kurz-Drexler, A. Kathrin Lutz, Daniela Vogt-Weisenhorn, Mareike E. Fett, Nicole Exner, Konstanze F. Winklhofer, Jörg Tatzelt
Publikováno v:
J. Biol. Chem. 284, 2108-2111 (2009)
The journal of biological chemistry 284(34), 22938-22951 (2009). doi:10.1074/jbc.M109.035774
The journal of biological chemistry 284(34), 22938-22951 (2009). doi:10.1074/jbc.M109.035774
Loss-of-function mutations in the parkin gene (PARK2) and PINK1 gene (PARK6) are associated with autosomal recessive parkinsonism. PINK1 deficiency was recently linked to mitochondrial pathology in human cells and Drosophila melanogaster, which can b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50c33d1f99c997e4a059702b425b71bd
https://doi.org/10.1074/jbc.m109.035774
https://doi.org/10.1074/jbc.m109.035774
Autor:
Durga Praveen Meka, Barbara Finckh, Anne Kathrin Müller-Rischart, Margit Miesbauer, Edgar R. Kramer, Prakash Nidadavolu, Jörg Tatzelt, Elisa Motori, Behnam Mohammadi, Konstanze F. Winklhofer, Natalie Rotermund, Anil Annamneedi, Srinivas Kumar Ponna, Mahmoud Bassal, Christian Lohr, Helia Aboutalebi
Publikováno v:
The journal of clinical investigation 125(5), 1873-1885 (2015). doi:10.1172/JCI79300
Parkin and the glial cell line–derived neurotrophic factor (GDNF) receptor RET have both been independently linked to the dopaminergic neuron degeneration that underlies Parkinson’s disease (PD). In the present study, we demonstrate that there is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22f821a4c83aa674096f906abc6dbe93
Autor:
Anna Pilsl, Konstanze F. Winklhofer
Publikováno v:
Acta neuropathologica 123(2), 173-188 (2011). doi:10.1007/s00401-011-0902-3
Mitochondria are dynamic organelles which are essential for many cellular processes, such as ATP production by oxidative phosphorylation, lipid metabolism, assembly of iron sulfur clusters, regulation of calcium homeostasis, and cell death pathways.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb5f7a6d2402ca1e2cf25fda82d46e0a