Zobrazeno 1 - 10
of 61
pro vyhledávání: '"physiology [Synapses]"'
Autor:
Hiroki Kawai, Gaia Tavosanis, Mélisande Richard, Karolína Doubková, Yohei Nitta, Atsushi Sugie
Publikováno v:
The journal of neuroscience 42(24), 4937-4952 (2022). doi:10.1523/JNEUROSCI.2115-21.2022
In human neurodegenerative diseases, neurons undergo axonal degeneration months to years before they die. Here, we developed a system modelling early degenerative events in Drosophila adult photoreceptor cells. Thanks to the stereotypy of their axona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af5e63deb40ec7833ca0a8678f951ff3
https://doi.org/10.1523/jneurosci.2115-21.2022
https://doi.org/10.1523/jneurosci.2115-21.2022
Autor:
E A Matthews, W Sun, S M McMahon, M Doengi, L Halka, S Anders, J A Müller, P Steinlein, N S Vana, G van Dyk, J Pitsch, A J Becker, A Pfeifer, E T Kavalali, A Lamprecht, C Henneberger, V Stein, S Schoch, D Dietrich
Publikováno v:
Cerebral cortex 32(17), 3669-3689 (2022). doi:10.1093/cercor/bhab440
Fast synaptic communication uses diffusible transmitters whose spread is limited by uptake mechanisms. However, on the submicron-scale, the distance between two synapses, the extent of glutamate spread has so far remained difficult to measure. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::683db48cfad0c945bcc14be2ebbe6a68
https://doi.org/10.1093/cercor/bhab440
https://doi.org/10.1093/cercor/bhab440
Publikováno v:
Trends in neurosciences 46(1), 32-44 (2023). doi:10.1016/j.tins.2022.10.012
The heterogeneity of the endoplasmic reticulum (ER) makes it a versatile platform for a broad range of homeostatic processes, ranging from calcium regulation to synthesis and trafficking of proteins and lipids. It is not surprising that neurons use t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b746ce885448ea25c9ad93807a0bd672
https://pubmed.ncbi.nlm.nih.gov/36428191
https://pubmed.ncbi.nlm.nih.gov/36428191
Autor:
Fabio Bertan, Lena Wischhof, Liudmila Sosulina, Manuel Mittag, Dennis Dalügge, Alessandra Fornarelli, Fabrizio Gardoni, Elena Marcello, Monica Di Luca, Martin Fuhrmann, Stefan Remy, Daniele Bano, Pierluigi Nicotera
Publikováno v:
Cell Death & Differentiation
Cell death and differentiation, 27(12):3354-3373
Cell Death and Differentiation
Cell death and differentiation 27(12), 3354-3373 (2020). doi:10.1038/s41418-020-0584-2
Cell death and differentiation, 27(12):3354-3373
Cell Death and Differentiation
Cell death and differentiation 27(12), 3354-3373 (2020). doi:10.1038/s41418-020-0584-2
Dendritic spines are postsynaptic domains that shape structural and functional properties of neurons. Upon neuronal activity, Ca2+ transients trigger signaling cascades that determine the plastic remodeling of dendritic spines, which modulate learnin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d0277fd5150bdb3eaabea65eab22dcf
https://doi.org/10.1038/s41418-020-0584-2
https://doi.org/10.1038/s41418-020-0584-2
Publikováno v:
Cell Reports, Vol 29, Iss 12, Pp 3767-3774.e3 (2019)
Cell reports 29(12), 3767-3774.e3 (2019). doi:10.1016/j.celrep.2019.11.060
Cell reports 29(12), 3767-3774.e3 (2019). doi:10.1016/j.celrep.2019.11.060
Summary: At presynaptic terminals, neurotransmitters are released by synaptic vesicle exocytosis at the active zone. In order to maintain efficient neurotransmission and proper synaptic structure, sites of vesicle fusion must be cleared rapidly by en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd3c34b5845e28d806fbd1f5fe5c25f9
http://www.sciencedirect.com/science/article/pii/S2211124719315517
http://www.sciencedirect.com/science/article/pii/S2211124719315517
Autor:
Yuhao Han, Michael R. Kreutz, Marina Mikhaylova, Eunjoon Kim, Alla S. Kostyukova, Stephan Niebling, Fatemeh Hassani Nia, Dmitry S. Molodenskiy, Hans-Jürgen Kreienkamp, Michael Bucher, Dmitri I. Svergun
Publikováno v:
eLife
eLife 10, e66165 (1-31) (2021). doi:10.7554/eLife.66165
eLife 10, e66165 (2021). doi:10.7554/eLife.66165
eLife, Vol 10 (2021)
eLife, 10:e66165
eLife 10, e66165 (1-31) (2021). doi:10.7554/eLife.66165
eLife 10, e66165 (2021). doi:10.7554/eLife.66165
eLife, Vol 10 (2021)
eLife, 10:e66165
eLife 10, e66165 (1-31) (2021). doi:10.7554/eLife.66165
Members of the SH3- and ankyrin repeat (SHANK) protein family are considered as master scaffolds of the postsynaptic density of glutamatergic synapses. Several missense mutations within the
Members of the SH3- and ankyrin repeat (SHANK) protein family are considered as master scaffolds of the postsynaptic density of glutamatergic synapses. Several missense mutations within the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bea38ad9a2bea38b867e11283680ee2
http://europepmc.org/articles/PMC8169116
http://europepmc.org/articles/PMC8169116
Autor:
Philipp Ranft, Gaia Tavosanis, J. Scott Lauritzen, Lothar Baltruschat, André Fiala, Davi D. Bock, Luigi Prisco
Publikováno v:
Cell Rep
Cell reports 34(11), 108871-(2021). doi:10.1016/j.celrep.2021.108871
Cell reports 34(11), 108871-(2021). doi:10.1016/j.celrep.2021.108871
The formation and consolidation of memories are complex phenomena involving synaptic plasticity, microcircuit reorganization, and the formation of multiple representations within distinct circuits. To gain insight into the structural aspects of memor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad68944dcbe50a4fd6f766fc98c5473e
https://europepmc.org/articles/PMC8515896/
https://europepmc.org/articles/PMC8515896/
Autor:
Tobias M. Boeckers, Chiara Verpelli, Ersilia Vinci, Massimo Mantegazza, Vania Broccoli, Alessandro Sessa, Paolo Scalmani, Benedetta Terragni, Lorenza Culotta
Publikováno v:
Journal of Neuroscience
Journal of Neuroscience, Society for Neuroscience, 2020, 40 (37), pp.7013-7026. ⟨10.1523/JNEUROSCI.2194-19.2020⟩
The journal of neuroscience 40(37), 7013-7026 (2020). doi:10.1523/JNEUROSCI.2194-19.2020
J Neurosci
Journal of Neuroscience, Society for Neuroscience, 2020, 40 (37), pp.7013-7026. ⟨10.1523/JNEUROSCI.2194-19.2020⟩
The journal of neuroscience 40(37), 7013-7026 (2020). doi:10.1523/JNEUROSCI.2194-19.2020
J Neurosci
Sulfotransferase 4A1 (SULT4A1) is a cytosolic sulfotransferase that is highly conserved across species and extensively expressed in the brain. However, the biological function of SULT4A1 is unclear. SULT4A1 has been implicated in several neuropsychia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3fd345cc27faa96a4807fe785c38e6a
https://hal.archives-ouvertes.fr/hal-03011735
https://hal.archives-ouvertes.fr/hal-03011735
Autor:
Alexander Dityatev, Elodie Chabrol, Matthew C. Walker, Rahul Kaushik, Marco Aurelio Lisboa Leite, Eleonora Lugarà, Gabriele Lignani
Publikováno v:
Epilepsia 61(12), 2836-2846 (2020). doi:10.1111/epi.16736
LGI1 (Leucine-Rich Glioma-Inactivated 1) is a secreted trans-synaptic protein that interacts presynaptically with Kv1.1 potassium channels and ADAM23, and postsynaptically, influencing AMPA receptors through a direct link with the ADAM22 cell adhesio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5bc1239d57936b6164d3fda515d94a8
https://pub.dzne.de/record/154234
https://pub.dzne.de/record/154234
Autor:
Nicholas Cole, Katrin Böhm, Lucie Bard, Monika Bijata, Schwab Mh, Bijata K, Compan, Andre Zeug, Cherkas, Jakub Wlodarczyk, Yvonne Schill, Abdel-Galil D, Dmitri A. Rusakov, Subhadip Basu, Olga Kopach, Evgeni Ponimaskin, Alexander Dityatev, Michiyuki Matsuda
Publikováno v:
Communications biology 3(1), 76 (2020). doi:10.1038/s42003-020-0791-x
Communications Biology, Vol 3, Iss 1, Pp 1-16 (2020)
Communications Biology, Vol 3, Iss 1, Pp 1-16 (2020)
Activity-dependent remodeling of excitatory connections underpins memory formation in the brain. Serotonin receptors are known to contribute to such remodeling, yet the underlying molecular machinery remains poorly understood. Here, we employ high-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbaaa183eeb5c3d111d335105bf6594d
https://pub.dzne.de/record/151632
https://pub.dzne.de/record/151632