Zobrazeno 1 - 10 of 28 pro vyhledávání: '"physiology [Pyramidal Cells]"'
1
Microcircuits for spatial coding in the medial entorhinal cortex
Autor: Prateep Beed, Richard Kempter, Michael Brecht, John J. Tukker, Edvard I. Moser, Dietmar Schmitz
Publikováno v: Physiological Reviews
Physiological reviews 102(2), 653-688 (2022). doi:10.1152/physrev.00042.2020
The hippocampal formation is critically involved in learning and memory and contains a large proportion of neurons encoding aspects of the organism’s spatial surroundings. In the medial entorhinal cortex (MEC), this includes grid cells with their d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::885d5f454253129192c1aa52c66a6211
https://doi.org/10.1152/physrev.00042.2020
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2
Generation of Sharp Wave-Ripple Events by Disinhibition
Autor: Nikolaus Maier, Claire Cooper, Gaspar Cano, Roberta Evangelista, Dietmar Schmitz, Richard Kempter
Publikováno v: The Journal of Neuroscience
The journal of neuroscience 40(41), 7811-7836 (2020). doi:10.1523/JNEUROSCI.2174-19.2020
Sharp wave-ripple complexes (SWRs) are hippocampal network phenomena involved in memory consolidation. To date, the mechanisms underlying their occurrence remain obscure. Here, we show how the interactions between pyramidal cells, parvalbumin-positiv
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a19be090b4955abe91550bd5b777d33c
http://europepmc.org/articles/PMC7548694
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3
O-LM interneurons: Gatekeepers of pyramidal neuron activity in the hippocampus
Autor: Poll, Stefanie, Fuhrmann, Martin
Publikováno v: Neuron 110(10), 1606-1608 (2022). doi:10.1016/j.neuron.2022.04.022
Neuron
A balanced and fine-tuned ratio of neuronal excitation and inhibition is a prerequisite for information processing. In this issue of Neuron, He et al. (2022) reveal a causal link between reduced input to local somatostatin-expressing, MeCP2-negative
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fabe90e229f210845e7c299a869efda9
https://pub.dzne.de/record/164047
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4
Interneuron switching on and off across memory rhythms
Autor: Alexandra Tzilivaki, Nikolaus Maier, Dietmar Schmitz
Publikováno v: Neuron 110(12), 1884-1886 (2022). doi:10.1016/j.neuron.2022.05.019
In this issue of Neuron, Szabo et al. uncover a unique subtype of interneurons that is highly active during ripples but largely silent during theta oscillations. The study provides exciting new insights into the regulation and propagation of ripples
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee41ea24aa86e5c68a1cda6332bcea70
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5
An astrocytic signaling loop for frequency-dependent control of dendritic integration and spatial learning
Autor: Kirsten Bohmbach, Nicola Masala, Eva M. Schönhense, Katharina Hill, André N. Haubrich, Andreas Zimmer, Thoralf Opitz, Heinz Beck, Christian Henneberger
Publikováno v: Nature Communications 13(1), 7932 (2022). doi:10.1038/s41467-022-35620-8
Dendrites of hippocampal CA1 pyramidal cells amplify clustered glutamatergic input by activation of voltage-gated sodium channels and N-methyl-D-aspartate receptors (NMDARs). NMDAR activity depends on the presence of NMDAR co-agonists such as D-serin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c8eeecb37800295e64926a02448fd6d
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6
Persistent Firing in Hippocampal CA1 Pyramidal Cells in Young and Aged Rats
Autor: Yacine Brahimi, Beate Knauer, Alan Tobias Price, Maria Jesus Valero-Aracama, Antonio Reboreda, Magdalena Sauvage, Motoharu Yoshida
Publikováno v: eNeuro, 10(3):ENEURO.0479-22.2023
eNeuro 10(3), ENEURO.0479-22.2023 (2023). doi:10.1523/ENEURO.0479-22.2023
Persistent neuronal firing is often observed in working memory and temporal association tasks both in humans and animals, and is believed to retain necessary information in these tasks. We have reported that hippocampal CA1 pyramidal cells are able t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8647811d19d6cbcf9748a06a62dcdda3
https://doi.org/10.1523/eneuro.0479-22.2023
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7
Spikelets in pyramidal neurons: generating mechanisms, distinguishing properties, and functional implications
Autor: Dietmar Schmitz, Michiel W. H. Remme, Martina Michalikova, Susanne Schreiber, Richard Kempter
Publikováno v: Reviews in the neurosciences 31(1), 101-119 (2019). doi:10.1515/revneuro-2019-0044
Spikelets are small spike-like depolarizations that are found in somatic recordings of many neuron types. Spikelets have been assigned important functions, ranging from neuronal synchronization to the regulation of synaptic plasticity, which are spec
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7878ae03bef0930ec907295aed095163
https://doi.org/10.1515/revneuro-2019-0044
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8
Switching between persistent firing and depolarization block in individual rat CA1 pyramidal neurons
Autor: Beate Knauer, Motoharu Yoshida
Publikováno v: Hippocampus 29(9), 817-835 (2019). doi:10.1002/hipo.23078
The hippocampal formation plays a role in mnemonic tasks and epileptic discharges in vivo. In vitro, these functions and malfunctions may relate to persistent firing (PF) and depolarization block (DB), respectively. Pyramidal neurons of the CA1 field
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f985149b4b4365875edba3bc9e2be38
https://doi.org/10.1002/hipo.23078
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9
Cav3 T-Type Voltage-Gated Ca2+ Channels and the Amyloidogenic Environment: Pathophysiology and Implications on Pharmacotherapy and Pharmacovigilance
Autor: Anna Papazoglou, Muhammad Imran Arshaad, Christina Henseler, Johanna Daubner, Karl Broich, Jürgen Hescheler, Dan Ehninger, Britta Haenisch, Marco Weiergräber
Publikováno v: International journal of molecular sciences, 23(7):3457
International journal of molecular sciences 23(7), 3457 (2022). doi:10.3390/ijms23073457
Voltage-gated Ca2+ channels (VGCCs) were reported to play a crucial role in neurotransmitter release, dendritic resonance phenomena and integration, and the regulation of gene expression. In the septohippocampal system, high- and low-voltage-activate
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c371abddf74beb198a354fd47ad85d6
https://doi.org/10.3390/ijms23073457
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10
Involvement of TRPC4 and 5 Channels in Persistent Firing in Hippocampal CA1 Pyramidal Cells
Autor: Arboit, Alberto, Reboreda, Antonio, Yoshida, Motoharu
Publikováno v: Cells
Cells, Vol 9, Iss 2, p 365 (2020)
Cells 9(2), 365 (2020). doi:10.3390/cells9020365
Cells, 9(2):365
Persistent neural activity has been observed in vivo during working memory tasks, and supports short-term (up to tens of seconds) retention of information. While synaptic and intrinsic cellular mechanisms of persistent firing have been proposed, unde
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::877db7d98c1c9e1d47ce4debe58f444e
https://pubmed.ncbi.nlm.nih.gov/32033274
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