Developmental GABA polarity switch and neuronal plasticity in Bioengineered Neuronal Organoids

Autor: Zafeiriou, Maria-Patapia, Bao, Guobin, Hudson, James, Halder, Rashi, Blenkle, Alica, Schreiber, Marie-Kristin, Fischer, Andre, Schild, Detlev, Zimmermann, Wolfram-Hubertus

Publikováno v: Nature Communications
Nature Communications 11(1), 3791 (2020). doi:10.1038/s41467-020-17521-w
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)

Brain organoids are promising tools for disease modeling and drug development. For proper neuronal network formation excitatory and inhibitory neurons as well as glia need to co-develop. Here, we report the directed self-organization of human induced

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ac7a12aa9624eccadf976c91dff699e9
http://europepmc.org/articles/PMC7391775