Zobrazeno 1 - 10
of 26
pro vyhledávání: '"physiology [Neural Stem Cells]"'
Autor:
Julia Schneider, Johannes Weigel, Marie‐Theres Wittmann, Pavel Svehla, Sebastian Ehrt, Fang Zheng, Tarek Elmzzahi, Julian Karpf, Lucía Paniagua‐Herranz, Onur Basak, Arif Ekici, Andre Reis, Christian Alzheimer, Felipe Ortega de la O, Sabine Liebscher, Ruth Beckervordersandforth
Publikováno v:
The EMBO journal 41(11), e110409 (2022). doi:10.15252/embj.2021110409
Astrocytes are highly abundant in the mammalian brain, and their functions are of vital importance for all aspects of development, adaption, and aging of the central nervous system (CNS). Mounting evidence indicates the important contributions of ast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aad920c92b77455d8f3447a120403285
https://doi.org/10.15252/embj.2021110409
https://doi.org/10.15252/embj.2021110409
Autor:
Gonzalo Arias-Gil, Gerd Kempermann, Benedetta Artegiani, Joanna M. Wasielewska, Gabriel Berdugo-Vega, Chi-Chieh Lee, Federico Calegari, Kentaroh Takagaki, Michael T. Lippert, Adrian López-Fernández
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Nature Communications, 11(1):135
Nature Communications 11(1), 135 (2020). doi:10.1038/s41467-019-14026-z
Nature Communications
Nature Communications, 11(1):135
Nature Communications 11(1), 135 (2020). doi:10.1038/s41467-019-14026-z
Functional plasticity of the brain decreases during ageing causing marked deficits in contextual learning, allocentric navigation and episodic memory. Adult neurogenesis is a prime example of hippocampal plasticity promoting the contextualisation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f8c45704bcf362ba69e3a7a7ea41de
https://doaj.org/article/053faa42850e4fdca82723e9f3346693
https://doaj.org/article/053faa42850e4fdca82723e9f3346693
Autor:
Soni, Abhinav, Klütsch, Diana, Hu, Xin, Houtman, Judith, Rund, Nicole, McCloskey, Asako, Mertens, Jerome, Schafer, Simon T., Amin, Hayder, Toda, Tomohisa
Publikováno v:
Cells, Vol 10, Iss 1894, p 1894 (2021)
Cells
Cells 10(8), 1894-(2021). doi:10.3390/cells10081894
Cells
Cells 10(8), 1894-(2021). doi:10.3390/cells10081894
Neuronal culture was used to investigate neuronal function in physiological and pathological conditions. Despite its inevitability, primary neuronal culture remained a gold standard method that requires laborious preparation, intensive training, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::23c607b5365bc9683fc635b797933ab6
https://www.mdpi.com/2073-4409/10/8/1894
https://www.mdpi.com/2073-4409/10/8/1894
Autor:
Jochen Roeper, Niklas Kleinenkuhnen, Malte Stockebrand, Marta Florio, Anna Katharina Schlusche, Igor Jakovcevski, Sabine Ulrike Vay, Steffi Sandke, Dirk Isbrandt, Achim Tresch, Wieland B. Huttner, Rafael Campos-Martin, Maria Adele Rueger
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America 118(35), e2009393118 (2021). doi:10.1073/pnas.2009393118
Proc Natl Acad Sci U S A
Proc Natl Acad Sci U S A
The development of the cerebral cortex relies on the controlled division of neural stem and progenitor cells. The requirement for precise spatiotemporal control of proliferation and cell fate places a high demand on the cell division machinery, and d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a71eaa9257832f436b89f3211d3ea06
https://pub.dzne.de/record/162815
https://pub.dzne.de/record/162815
Autor:
Danielyan, Lusine, Schwab, Matthias, Krueger, Marcel A., Calaminus, Carsten, Naumann, Ulrike, Winter, Stefan, Schaeffeler, Elke, Spogis, Annett, Beer-Hammer, Sandra, Neher, Jonas J., Spohn, Gabriele, Kretschmer, Anja, Siegel, Georg, Krämer-Albers, Eva-Maria, Barth, Kerstin, Lee, Hong Jun, Kim, Seung U., Frey, William H., Claussen, Claus D., Hermann, Dirk M., Doeppner, Thorsten R., Seifried, Erhard, Gleiter, Christoph H., Brawek, Bianca, Northoff, Hinnak, Schäfer, Richard, Garaschuk, Olga, Asavapanumas, Nithi, Buadze, Marine, Lourhmati, Ali, Wendel, Hans-Peter, Avci-Adali, Meltem
Publikováno v:
EBioMedicine, Vol 60, Iss, Pp 102989-(2020)
EBioMedicine
EBioMedicine 60, 102989-(2020). doi:10.1016/j.ebiom.2020.102989
EBioMedicine
EBioMedicine 60, 102989-(2020). doi:10.1016/j.ebiom.2020.102989
Background: Stem cells‘ (SC) functional heterogeneity and its poorly understood aetiology impedes clinical development of cell-based therapies in regenerative medicine and oncology. Recent studies suggest a strong correlation between the SC migrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::3667662807e8d4d6581fe2cfe0ec57af
http://www.sciencedirect.com/science/article/pii/S2352396420303650
http://www.sciencedirect.com/science/article/pii/S2352396420303650
Autor:
Sevgican Yilmaz, Kerstin Brandt, Stanislava Popova, Nambirajan Govindarajan, Violeta Mashkaryan, Mehmet Ilyas Cosacak, Yixin Zhang, Prabesh Bhattarai, Caghan Kizil
Publikováno v:
PLoS biology 18(1), e3000585 (2020). doi:10.1371/journal.pbio.3000585
PLoS Biology, Vol 18, Iss 1, p e3000585 (2020)
PLoS Biology
PLoS Biology, Vol 18, Iss 1, p e3000585 (2020)
PLoS Biology
It was recently suggested that supplying the brain with new neurons could counteract Alzheimer’s disease (AD). This provocative idea requires further testing in experimental models in which the molecular basis of disease-induced neuronal regenerati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b7128d34c3abdc93eb8e578ba77c92c
Autor:
Schweyer, Kerstin, Rüschoff-Steiner, Corinna, Arias-Carrión, Oscar, Oertel, Wolfgang H, Rösler, Thomas W, Höglinger, Günter
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific reports 9(1), 13359 (2019). doi:10.1038/s41598-019-49920-5
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific reports 9(1), 13359 (2019). doi:10.1038/s41598-019-49920-5
Neuroblasts born in the subventricular zone of adult mammals migrate via the rostral migratory stream into the granular cell layer or periglomerular layer of the olfactory bulb to differentiate into interneurons. To analyze if new neurons in the gran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::1417a03b56be5e867f53f0eaae611d26
https://pubmed.ncbi.nlm.nih.gov/31527656
https://pubmed.ncbi.nlm.nih.gov/31527656
Autor:
Igor Jakovcevski, Radmila Filipovic, J. Alberto Ortega, Nevena V. Radonjić, Nada Zecevic, Inseyah Bagasrawala, Fani Memi
Publikováno v:
The neuroscientist 24(2), 156-170 (2017). doi:10.1177/1073858417691009
One of the main characteristics of the developing brain is that all neurons and the majority of macroglia originate first in the ventricular zone (VZ), next to the lumen of the cerebral ventricles, and later on in a secondary germinal area above the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2a71253bcab56c619f2fe79da3cfbfa
Autor:
Axel Roers, Joanna M. Wasielewska, Lukas Donix, Tara L. Walker, Nicole Rund, Ruslan Rust, Lisa Grönnert, Gerd Kempermann, Alex M. Sykes, Anja Hoppe
Publikováno v:
Scientific Reports
Scientific reports 7(1), 17859 (2017). doi:10.1038/s41598-017-18184-2
Scientific Reports, 7
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific reports 7(1), 17859 (2017). doi:10.1038/s41598-017-18184-2
Scientific Reports, 7
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
There is growing evidence that both peripheral and resident immune cells play an important part in regulating adult neural stem cell proliferation and neurogenesis, although the contribution of the various immune cell types is still unclear. Mast cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfcdc309cddddfec5a86550530d977aa
http://europepmc.org/articles/PMC5736663
http://europepmc.org/articles/PMC5736663
Autor:
Christopher L. Antos, Laura J. Bray, Hilal Celikkaya, Alvin Kuriakose Thomas, Weilin Lin, Christos Papadimitriou, Yixin Zhang, Caghan Kizil, Heike Hollak, Uwe Freudenberg, Xin Chen, Thomas Kurth, Violeta Mashkaryan, Shuijin He, Mehmet Ilyas Cosacak, Prabesh Bhattarai, Kerstin Brandt, Andreas Dahl, Carsten Werner, Jens Friedrichs
Publikováno v:
Developmental cell 46(1), 85-101.e8 (2018). doi:10.1016/j.devcel.2018.06.005
Neural stem cells (NSCs) constitute an endogenous reservoir for neurons that could potentially be harnessed for regenerative therapies in disease contexts such as neurodegeneration. However, in Alzheimer's disease (AD), NSCs lose plasticity and thus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1db474d0123c710a4a7d850c8dca8603
https://pubmed.ncbi.nlm.nih.gov/29974866
https://pubmed.ncbi.nlm.nih.gov/29974866