Zobrazeno 1 - 10
of 19
pro vyhledávání: '"physiology [Membrane Potentials]"'
Autor:
Dietmar Schmitz, Benjamin R. Rost, Daniel Parthier, Alexander Stumpf, Rosanna P. Sammons, A. Vanessa Stempel, Jörg Breustedt
Publikováno v:
Neuropharmacology 139, 217-225 (2018). doi:10.1016/j.neuropharm.2018.07.020
Neuropharmacology
Neuropharmacology
Endogenous cannabinoids are diffusible lipid ligands of the main cannabinoid receptors type 1 and 2 (CB1R and CB2R). In the central nervous system endocannabinoids are produced in an activity-dependent manner and have been identified as retrograde mo
Autor:
Lilian Staerck, Golo Kronenberg, Helmut Kettenmann, Friederike Klempin, Stephanie Wegner, Karen Gertz, Wolfgang Uckert, Nadine Richter, Matthias Endres, Ria Uhlemann, Susanne A. Wolf
Publikováno v:
Acta neuropathologica 135(4), 551-568 (2017). doi:10.1007/s00401-017-1795-6
After stroke, macrophages in the ischemic brain may be derived from either resident microglia or infiltrating monocytes. Using bone marrow (BM)-chimerism and dual-reporter transgenic fate mapping, we here set out to delimit the responses of either ce
Autor:
Steffen Kautzmann, Anne Boehlen, Christian Henneberger, Christian Steinhäuser, Björn Breithausen
Publikováno v:
Glia 68(5), 918-931 (2019). doi:10.1002/glia.23751
Astrocytes form large networks, in which individual cells are connected via gap junctions. It is thought that this astroglial gap junction coupling contributes to the buffering of extracellular K+ increases. However, it is largely unknown how the con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0af3b715b32b7680e9be4af85e37d222
https://pub.dzne.de/record/141697
https://pub.dzne.de/record/141697
Autor:
Martin Biel, Mathias W. Seeliger, Sabrina Asteriti, Christian Schön, Vithiyanjali Sothilingam, Jochen Herms, Stylianos Michalakis, Naoyuki Tanimoto, Susanne Koch, Marina Garcia Garrido, Lorenzo Cangiano
Publikováno v:
Human molecular genetics 25(6), 1165-1175 (2016). doi:10.1093/hmg/ddv639
Most inherited blinding diseases are characterized by compromised retinal function and progressive degeneration of photoreceptors. However, the factors that affect the life span of photoreceptors in such degenerative retinal diseases are rather poorl
Autor:
Nicolas Singewald, Christine Strippel, Ludmila Sosulina, Maren D. Lange, Tatyana Kanyshkova, Simone B. Sartori, Achim Leonhard Walter, Hans-Christian Pape, Hector Romo-Parra
Publikováno v:
Journal of neurophysiology 114(4), 2500-2508 (2015). doi:10.1152/jn.00883.2014
Substance P (SP) is implicated in stress regulation and affective and anxiety-related behavior. Particularly high expression has been found in the main output region of the amygdala complex, the central amygdala (CE). Here we investigated the cellula
Autor:
Christian Steinhäuser, Peter Bedner, Monika Plescher, Gerald Seifert, Jan N. Hansen, Annett Halle
Publikováno v:
Glia 66(7), 1464-1480 (2018). doi:10.1002/glia.23318
Microglia, the central nervous system resident innate immune cells, cluster around Aβ plaques in Alzheimer's disease (AD). The activation phenotype of these plaque-associated microglial cells, and their differences to microglia distant to Aβ plaque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0878bbd2890adcd02fe378cc02bf0954
Autor:
Bárbara Oliveira, Ralf Trippe, Daniel Tapken, Michael Hollmann, S. Bertrand, Wolfram-Hubertus Zimmermann, B. Jurek, Johann Steiner, P. Zafeiriou, Hong Pan, Christina Klein-Schmidt, Harald Prüss, Esther Castillo-Gómez, D. Bertrand, Hannelore Ehrenreich
Publikováno v:
Molecular Psychiatry
Molecular psychiatry 22(12), 1776-1784 (2017). doi:10.1038/mp.2016.125
Molecular psychiatry 22(12), 1776-1784 (2017). doi:10.1038/mp.2016.125
Autoantibodies of the IgG class against N-methyl-d-aspartate-receptor subunit NR1 (NMDAR1) were first described in anti-NMDAR encephalitis and seen as disease indicators. Recent work on together over 5000 individuals challenged this exclusive view by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20f26af22236dc55af7d265aea225e2f
https://hdl.handle.net/11858/00-001M-0000-002C-0F24-811858/00-001M-0000-002C-0F22-C
https://hdl.handle.net/11858/00-001M-0000-002C-0F24-811858/00-001M-0000-002C-0F22-C
Autor:
Giulio Sancini, Mauro Toselli, R. Rusconi, Chiara Villa, Daniele Grioni, Veronica Sansoni, Francesca Talpo, Massimo Mantegazza, N. Binini, R Dal Magro, Romina Combi
Publikováno v:
Brain research 1677, 26-32 (2017). doi:10.1016/j.brainres.2017.09.023
Mutations in the SCN1A gene causing either loss or gain of function have been frequently found in patients affected by genetic epilepsy with febrile seizures plus (GEFS+) or Dravet syndrome (also named severe myoclonic epilepsy in infancy SMEI). By m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18ae09fc3161001c10f2d213d8c0d121
Autor:
David Michod, Amel F Khelifi, Stefano Bartesaghi, Cristian Bellodi, Pierluigi Nicotera, Laura Berliocchi, Paolo Salomoni
Publikováno v:
Neuron
Neuron 74(1), 122-135 (2012). doi:10.1016/j.neuron.2012.02.021
Neuron 74(1), 122-135 (2012). doi:10.1016/j.neuron.2012.02.021
Summary Activity-dependent modifications of chromatin are believed to contribute to dramatic changes in neuronal circuitry. The mechanisms underlying these modifications are not fully understood. The histone variant H3.3 is incorporated in a replicat
Autor:
Matthias Eder, Charilaos Avrabos, Gregor von Wolff, Jens Stepan, Jan M. Deussing, Wolfgang Wurst, Florian Holsboer
Publikováno v:
Journal of psychiatric research 45(2), 256-261 (2011). doi:10.1016/j.jpsychires.2010.06.007
Corticotropin-releasing hormone (CRH) is thought to play an important role in the pathophysiology of stress-related psychiatric disorders, such as major depressive disorder (MDD) and post-traumatic stress disorder (PTSD). However, knowledge about the