Zobrazeno 1 - 10
of 40
pro vyhledávání: '"physiology [Gene Expression Regulation]"'
Autor:
Simon Mead, Simone Hornemann, Marc Emmenegger, Elke Schaper, Kevin Maggi, Peter Heutink, Jiang-An Yin, Anna Spinelli, Ashutosh Dhingra, Daniel Heinzer, Berre Doğançay, Merve Avar, Daniel Patrick Pease, Adriano Aguzzi, Andra Chincisan
Publikováno v:
PLoS Pathogens, Vol 17, Iss 10 (2021)
PLoS pathogens 17(10), e1010013 (2021). doi:10.1371/journal.ppat.1010013
PLoS Pathogens, Vol 17, Iss 10, p e1010013 (2021)
PLoS Pathogens
PLoS pathogens 17(10), e1010013 (2021). doi:10.1371/journal.ppat.1010013
PLoS Pathogens, Vol 17, Iss 10, p e1010013 (2021)
PLoS Pathogens
The cellular prion protein PrPC is necessary for prion replication, and its reduction greatly increases life expectancy in animal models of prion infection. Hence the factors controlling the levels of PrPC may represent therapeutic targets against hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59f070e22194fd9e3258e126ce44b9be
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575309/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575309/?tool=EBI
Achieving functional neuronal dendrite structure through sequential stochastic growth and retraction
Autor:
Gaia Tavosanis, Amirhoushang Bahrami, Tomke Stürner, Lothar Baltruschat, Peter Jedlicka, Hermann Cuntz, André Ferreira Castro
Publikováno v:
eLife
eLife 9, e60920 (2020). doi:10.7554/eLife.60920
eLife, Vol 9 (2020)
eLife 9, e60920 (2020). doi:10.7554/eLife.60920
eLife, Vol 9 (2020)
Class I ventral posterior dendritic arborisation (c1vpda) proprioceptive sensory neurons respond to contractions in theDrosophilalarval body wall during crawling. Their dendritic branches run along the direction of contraction, possibly a functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0fa177ac7241598ea1a17462d80a4c8
https://doi.org/10.7554/elife.60920
https://doi.org/10.7554/elife.60920
Autor:
Andrea Pfennig, Alexander Storch, Cathrin Sauer, Michael Bauer, Wiebke Schrempf, Moritz D. Brandt, Franciska Brezan, Philipp Ritter, Annegret Krupka, Bettina Soltmann
Publikováno v:
Journal of affective disorders 239, 152-160 (2018). doi:10.1016/j.jad.2018.06.037
Objective Bipolar disorder is a severe mental disorder associated with persistent sleep disturbances and elevated levels of mRNA coding for pro-inflammatory cytokines within peripheral monocytes. The mechanisms causing and sustaining a reduced sleep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a386666f56b8b87a92b0aee1618a45d
https://doi.org/10.1016/j.jad.2018.06.037
https://doi.org/10.1016/j.jad.2018.06.037
Autor:
Thomas Meyer, Sebastian Kügler, Jens Christian Schwamborn, Isabel Paiva, Luis Fonseca-Ornelas, Francesca Odoardi, Markus Zweckstetter, Johannes Attems, Kristina Gotovac Jerčić, Cemil Kerimoglu, Christiane Fahlbusch, Anna Villar-Piqué, Andre Fischer, Wolfgang Fischle, Isidre Ferrer, Ellen Gerhardt, Tiago F. Outeiro, Szabolcs Soeroes, Tomás Lopes da Fonseca, Stefan Becker, Maria Angeliki S. Pavlou, Ana Cristina Rego, Éva M. Szegö, Raquel Pinho, Fran Borovečki, Paula Garcia-Esparcia
Publikováno v:
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Human molecular genetics 28(1), 31-50 (2019). doi:10.1093/hmg/ddy326
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Human molecular genetics 28(1), 31-50 (2019). doi:10.1093/hmg/ddy326
Alpha-synuclein (aSyn) is a central player in Parkinson’s disease (PD) but the precise molecular mechanisms underlying its pathogenicity remain unclear. It has recently been suggested that nuclear aSyn may modulate gene expression, possibly via int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3a19eeeb3bdd16a38fa2188d795df46
https://doi.org/10.1093/hmg/ddy326
https://doi.org/10.1093/hmg/ddy326
Autor:
Joachim Täger, Bernd Wissinger, David G. Birch, Peggy Reuter, Dianna K H Wheaton, Susanne Kohl
Publikováno v:
Experimental eye research 171, 48-53 (2018). doi:10.1016/j.exer.2018.02.027
The cyclic nucleotide-gated (CNG) channel - composed of CNGA3 and CNGB3 subunits - mediates the influx of cations in cone photoreceptors after light stimulation and thus is a key element in cone phototransduction. Mutations in CNGA3 and CNGB3 are ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::913fb077fa2128595b44312de13b481b
https://doi.org/10.1016/j.exer.2018.02.027
https://doi.org/10.1016/j.exer.2018.02.027
Autor:
Chantal Sellier, Nick H.M. van Bakel, Amila Zuko, Céline Sijlmans, Sina Mersmann, Anne-Laurence Boutillier, Annemarie Hübers, Amr Aly, Marina Wagner, Stéphane Dieterlé, Moushami Mallik, Marc-Antoine Goy, Clotilde Lagier-Tourenne, Gina Picchiarelli, Albert C. Ludolph, Luc Dupuis, Erik Storkebaum, Julia Higelin, Angela Rosenbohm, Li Zhang, Tobias M. Boeckers, Marije Been, Maria Demestre, Jelena Scekic-Zahirovic, Nadia Messaddeq, Inmaculada Sanjuan-Ruiz
Publikováno v:
Nature Neuroscience
Nature Neuroscience, Nature Publishing Group, 2019, 22 (11), pp.1793-1805. ⟨10.1038/s41593-019-0498-9⟩
Nature neuroscience
Nature Neuroscience, 22, 1793-1805
Nature reviews / Neuroscience 22(11), 1793-1805 (2019). doi:10.1038/s41593-019-0498-9
Nature Neuroscience, 22, 11, pp. 1793-1805
Nature Neuroscience, Nature Publishing Group, 2019, 22 (11), pp.1793-1805. ⟨10.1038/s41593-019-0498-9⟩
Nature neuroscience
Nature Neuroscience, 22, 1793-1805
Nature reviews / Neuroscience 22(11), 1793-1805 (2019). doi:10.1038/s41593-019-0498-9
Nature Neuroscience, 22, 11, pp. 1793-1805
Neuromuscular junction (NMJ) disruption is an early pathogenic event in amyotrophic lateral sclerosis (ALS). Yet, direct links between NMJ pathways and ALS-associated genes such as FUS, whose heterozygous mutations cause aggressive forms of ALS, rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a29ee2725324cd47aad72a1d21ded34f
https://hal.archives-ouvertes.fr/hal-02406369
https://hal.archives-ouvertes.fr/hal-02406369
Autor:
Thilo Kähne, Constanze I. Seidenbecher, Rainer Pielot, Angela Kolodziej, Wolfgang Tischmeyer, Michael Naumann, Sandra Richter, Karl-Heinz Smalla, Alexander Engler, Eckart D. Gundelfinger, Frank W. Ohl, Daniela C. Dieterich
Publikováno v:
Journal of Neurochemistry
Journal of neurochemistry 138(1), 124-138 (2016). doi:10.1111/jnc.13636
Journal of neurochemistry, 138(1):13636
Journal of neurochemistry 138(1), 124-138 (2016). doi:10.1111/jnc.13636
Journal of neurochemistry, 138(1):13636
Learning and memory processes are accompanied by rearrangements of synaptic protein networks. While various studies have demonstrated the regulation of individual synaptic proteins during these processes, much less is known about the complex regulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::befc2f74a119d49e72c634de9641027e
http://europepmc.org/articles/PMC5089584
http://europepmc.org/articles/PMC5089584
Autor:
Sabine Graf, Dietmar Kuhl, Ora Ohana, Ute Süsens, Sergio Castro-Gomez, Dirk Isbrandt, Jasper Grendel, Daniel Mensching, Xiaoyan Gao, Lars Binkle
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America 115(49), 12531-12536 (2018). doi:10.1073/pnas.1810125115
During early postnatal development, sensory regions of the brain undergo periods of heightened plasticity which sculpt neural networks and lay the foundation for adult sensory perception. Such critical periods were also postulated for learning and me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb51dd33955d0b6e82fd65d4e58f22ac
https://pub.dzne.de/record/140363
https://pub.dzne.de/record/140363
Publikováno v:
Glia 65(2), 375-387 (2016). doi:10.1002/glia.23097
Microglia are resident immune cells in the central nervous system (CNS), which are essential for immune defence and critically contribute to neuronal functions during homeostasis. Until now, little is known about microglia biology in humans in part d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_____10678::cd8ea798c3c7b9d79f566b63abdc799a
https://pub.dzne.de/record/139028
https://pub.dzne.de/record/139028
Autor:
Basma Sukkar, Meinrad Gawaz, Florian Lang, Hajar Fakhri, Hang Cao, Itishri Sahu, Ravi Kumar Gutti, Lisann Pelzl, Stefan Hauser, Tamer Al-Maghout
Publikováno v:
The FASEB journal 31(8), 3439-3448 (2017). doi:10.1096/fj.201601211R
The transcription factor nuclear factor of activated T cells 5 (NFAT5) is up-regulated in several clinical disorders, including dehydration. NFAT5-sensitive genes include serum and glucocorticoid-inducible kinase 1 (SGK1). The kinase is a powerful re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::033aca978f1f1f33d65fa7378bf6b83c
https://pub.dzne.de/record/139397
https://pub.dzne.de/record/139397